STRINGSTRING
KRAS KRAS NRAS NRAS PPP3CA PPP3CA GRM5 GRM5 PPP3CB PPP3CB ADCY8 ADCY8 CAMK4 CAMK4 GRM1 GRM1 PRKCB PRKCB MAP2K1 MAP2K1 ADCY1 ADCY1 CALM1 CALM1 CALM2 CALM2 GRIA2 GRIA2 PPP3CC PPP3CC RAF1 RAF1 GRIN2C GRIN2C CAMK2A CAMK2A GRIN2B GRIN2B PPP1CC PPP1CC EP300 EP300 GRIA1 GRIA1 ITPR2 ITPR2 MAPK1 MAPK1 RAP1A RAP1A Prkaca Prkaca HRAS HRAS Rap1b Rap1b ENSCPOP00000032059 ENSCPOP00000032059 PPP3R1 PPP3R1 CSDE1 CSDE1 CREBBP CREBBP BRAF BRAF Camk2d Camk2d ITPR1 ITPR1 PLCB2 PLCB2 PLCB4 PLCB4 ENSCPOP00000028762 ENSCPOP00000028762 ENSCPOP00000028569 ENSCPOP00000028569 CALM3 CALM3 GRIN2D GRIN2D GNAQ GNAQ PRKACB PRKACB GRIN1 GRIN1 RAPGEF3 RAPGEF3 PRKCG PRKCG MAPK3 MAPK3 PPP1R1A PPP1R1A CALML4 CALML4 PPP1CB PPP1CB LOC100713271 LOC100713271 PLCB1 PLCB1 PPP1CA PPP1CA RPS6KA1 RPS6KA1 CACNA1C CACNA1C CAMK2G CAMK2G RPS6KA3 RPS6KA3 RPS6KA2 RPS6KA2 PLCB3 PLCB3 H0VKV0_CAVPO H0VKV0_CAVPO ITPR3 ITPR3 ARSI ARSI CAMK2B CAMK2B H0VX85_CAVPO H0VX85_CAVPO ATF4 ATF4 MAP2K2 MAP2K2 PRKCA PRKCA CALML3 CALML3 GRIN2A GRIN2A ARAF ARAF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRASKRAS proto-oncogene, GTPase. (189 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
PPP3CASerine/threonine-protein phosphatase. (518 aa)
GRM5Glutamate metabotropic receptor 5. (873 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (418 aa)
GRM1Glutamate metabotropic receptor 1. (1195 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ADCY1Adenylate cyclase 1. (944 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (194 aa)
CALM2Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
PPP3CCSerine/threonine-protein phosphatase. (481 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1209 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1381 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
EP300E1A binding protein p300. (2425 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (861 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
Rap1bUncharacterized protein. (184 aa)
ENSCPOP00000032059Uncharacterized protein; Belongs to the calmodulin family. (73 aa)
PPP3R1Uncharacterized protein. (169 aa)
CSDE1Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa)
CREBBPCREB binding protein. (2441 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (738 aa)
Camk2dProtein kinase domain-containing protein. (532 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ENSCPOP00000028762Uncharacterized protein. (107 aa)
ENSCPOP00000028569ANF_receptor domain-containing protein. (260 aa)
CALM3Calmodulin 3. (149 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (808 aa)
GNAQG protein subunit alpha q. (313 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (926 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PPP1R1AProtein phosphatase 1 regulatory inhibitor subunit 1A. (183 aa)
CALML4Calmodulin like 4. (153 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
LOC100713271Uncharacterized protein. (165 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2089 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (545 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
H0VKV0_CAVPOUncharacterized protein; Belongs to the calmodulin family. (139 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa)
ARSIArylsulfatase family member I. (572 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (659 aa)
H0VX85_CAVPOUncharacterized protein. (184 aa)
ATF4Activating transcription factor 4. (354 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1462 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (608 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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