Your Input: | |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | MAPK10 | Mitogen-activated protein kinase 10. (434 aa) |
| | Prkaca | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | ARRB2 | Arrestin beta 2. (417 aa) |
| | CSDE1 | Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa) |
| | MFF | Mitochondrial fission factor. (354 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ENSCPOP00000031524 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa) |
| | LOC100732436 | Uncharacterized protein. (327 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | ENSCPOP00000030527 | Uncharacterized protein. (111 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (388 aa) |
| | ENSCPOP00000030509 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | LOC100734206 | Uncharacterized protein. (461 aa) |
| | GNAI1 | Uncharacterized protein. (330 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (206 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (208 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | ATF6B | Activating transcription factor 6 beta. (694 aa) |
| | Vegfa | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (186 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | Gng5 | G protein gamma domain-containing protein. (41 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | GNAO1 | G protein subunit alpha o1. (318 aa) |
| | ARRB1 | Arrestin beta 1. (430 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (385 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | LOC100732158 | Uncharacterized protein. (246 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (253 aa) |
| | H0WBW4_CAVPO | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | LOC100718831 | YccV-like domain-containing protein. (514 aa) |
| | MMP2 | Matrix metallopeptidase 2. (662 aa) |
| | SHC1 | SHC adaptor protein 1. (583 aa) |
| | SHC3 | SHC adaptor protein 3. (418 aa) |
| | Insl3 | IlGF domain-containing protein. (132 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | LOC100723025 | Uncharacterized protein. (431 aa) |
| | NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1149 aa) |
| | H0W027_CAVPO | Uncharacterized protein. (722 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (549 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (459 aa) |
| | GNB2 | G protein subunit beta 2. (378 aa) |
| | COL4A1 | Collagen type IV alpha 1 chain. (1658 aa) |
| | ATF4 | Activating transcription factor 4. (354 aa) |
| | Rxfp1 | Relaxin/insulin-like family peptide receptor 1. (755 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (470 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (415 aa) |
| | COL4A6 | Collagen type IV alpha 6 chain. (1687 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (386 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | H0VQE0_CAVPO | Uncharacterized protein. (312 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1032 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (461 aa) |
| | GNB5 | G protein subunit beta 5. (406 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (325 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) |
| | ACTA2 | Actin alpha 2, smooth muscle. (377 aa) |
| | GNAI3 | Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] (354 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | NRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1287 aa) |
| | COL4A2 | Collagen type IV alpha 2 chain. (1479 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (419 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (522 aa) |
| | H0VE70_CAVPO | Uncharacterized protein. (796 aa) |
| | RXFP2 | Relaxin family peptide receptor 2. (737 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (967 aa) |
| | MMP9 | Matrix metallopeptidase 9. (715 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (1462 aa) |
| | PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa) |
| | MMP1 | Matrix metallopeptidase 1. (472 aa) |
| | Shc4 | Uncharacterized protein. (372 aa) |
| | CEP152 | Centrosomal protein 152. (1666 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa) |
| | PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) |
| | GNB1 | Beta-transducin. (340 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | Gna15 | Uncharacterized protein. (205 aa) |
| | NOS3 | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity); Belongs to the NOS family. (1206 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (348 aa) |
| | H0V1A0_CAVPO | YccV-like domain-containing protein. (541 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1454 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | ADCY1 | Adenylate cyclase 1. (944 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa) |
| | RLN | Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. It bears mature young, and allows separation of the pelvic bones; Belongs to the insulin family. (184 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa) |
| | COL4A4 | Collagen type IV alpha 4 chain. (1686 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (384 aa) |
| | MMP13 | Matrix metallopeptidase 13. (471 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1214 aa) |
