STRINGSTRING
RAB3D RAB3D PLA2G2A PLA2G2A LOC100717936 LOC100717936 CPB2 CPB2 LOC100727546 LOC100727546 CPB1 CPB1 CPA3 CPA3 ATP2A1 ATP2A1 OVCH2 OVCH2 TPCN2 TPCN2 CEL CEL ADCY1 ADCY1 PNLIPRP2 PNLIPRP2 TRPC1 TRPC1 PRKCB PRKCB ATP1B3 ATP1B3 PLA2G12A PLA2G12A PRSS37 PRSS37 CELA1 CELA1 PTRHD1 PTRHD1 ADCY3 ADCY3 CCKAR CCKAR ADCY8 ADCY8 H0V9U3_CAVPO H0V9U3_CAVPO ATP2A3 ATP2A3 CA2 CA2 LOC100379576 LOC100379576 CPA2 CPA2 PLA2G2D PLA2G2D H0VE70_CAVPO H0VE70_CAVPO PLA2G2E PLA2G2E Atp1a3 Atp1a3 ADCY2 ADCY2 CPA6 CPA6 PLA2G3 PLA2G3 ITPR2 ITPR2 CFTR CFTR PNLIP PNLIP ADCY5 ADCY5 ADCY4 ADCY4 SLC12A2 SLC12A2 RHOC RHOC SLC26A3 SLC26A3 PRKCA PRKCA CLCA2 CLCA2 CLCA1 CLCA1 LOC100727821 LOC100727821 LOC100726159 LOC100726159 SCTR SCTR LOC100735470 LOC100735470 PLA2G12B PLA2G12B LOC100717471 LOC100717471 Bst1 Bst1 KCNQ1 KCNQ1 H0VWZ0_CAVPO H0VWZ0_CAVPO PLA2G10 PLA2G10 H0VX85_CAVPO H0VX85_CAVPO Slc4a4 Slc4a4 Chrm3 Chrm3 SCT SCT H0W3H9_CAVPO H0W3H9_CAVPO ATP2B2 ATP2B2 ITPR3 ITPR3 Fxyd2 Fxyd2 H0WB32_CAVPO H0WB32_CAVPO PLCB3 PLCB3 RAB11A RAB11A LOC100732158 LOC100732158 PLA2G2C PLA2G2C CCK CCK RAC1 RAC1 ATP2B1 ATP2B1 LOC100724525 LOC100724525 PLCB1 PLCB1 ATP2B4 ATP2B4 LOC100713271 LOC100713271 ATP1A4 ATP1A4 ATP2A2 ATP2A2 PRKCG PRKCG ATP1B2 ATP1B2 CPA1 CPA1 CPA4 CPA4 ATP1B4 ATP1B4 ENSCPOP00000025593 ENSCPOP00000025593 ADCY9 ADCY9 ATP1A1 ATP1A1 GNAQ GNAQ KCNMA1 KCNMA1 ADCY6 ADCY6 RYR2 RYR2 ADCY7 ADCY7 SLC9A1 SLC9A1 ATP1B1 ATP1B1 ENSCPOP00000028762 ENSCPOP00000028762 ENSCPOP00000028852 ENSCPOP00000028852 PLCB4 PLCB4 ATP1A2 ATP1A2 PLCB2 PLCB2 SLC4A2 SLC4A2 PLA2G2F PLA2G2F ENSCPOP00000029947 ENSCPOP00000029947 LOC100715239 LOC100715239 ITPR1 ITPR1 ATP2B3 ATP2B3 RHOA RHOA LOC100732436 LOC100732436 RAB8A RAB8A PLA2G5 PLA2G5 Rap1b Rap1b RAB27A RAB27A PLA2G1B PLA2G1B LOC100715518 LOC100715518 RAB27B RAB27B RAP1A RAP1A CTRC CTRC
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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Your Input:
RAB3DRAB3D, member RAS oncogene family. (219 aa)
PLA2G2APhospholipase A2, membrane associated; Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins. Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1. Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1. Induces cell proliferat [...] (145 aa)
LOC100717936Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (297 aa)
CPB2Carboxypeptidase B2. (423 aa)
LOC100727546VWFA domain-containing protein. (923 aa)
CPB1Carboxypeptidase B1. (416 aa)
CPA3Carboxypeptidase A3. (416 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
OVCH2Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family. (567 aa)
TPCN2Two pore channel 2. (752 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (594 aa)
ADCY1Adenylate cyclase 1. (944 aa)
PNLIPRP2Pancreatic lipase-related protein 2; Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts preferentially on monoglycerides, phospholipids and galactolipids. Contributes to milk fat hydrolysis (By similarity); Belongs to the AB hydrolase superfamily. Lipase family. (451 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (810 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known (By similarity); Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
PLA2G12APhospholipase A2 group XIIA. (195 aa)
PRSS37Serine protease 37. (235 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (266 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
CCKARCholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (430 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
H0V9U3_CAVPOPhospholipase A(2). (146 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1028 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (249 aa)
LOC100379576Pre-trypsinogen isoform 1; Belongs to the peptidase S1 family. (246 aa)
CPA2Carboxypeptidase A2. (417 aa)
PLA2G2DPhospholipase A(2). (159 aa)
H0VE70_CAVPOUncharacterized protein. (796 aa)
PLA2G2EPhospholipase A(2). (152 aa)
Atp1a3Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
CPA6Carboxypeptidase A6. (438 aa)
PLA2G3Phospholipase A2 group III. (645 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
PNLIPPancreatic triacylglycerol lipase. (428 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1032 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
SLC12A2Solute carrier family 12 member 2. (1136 aa)
RHOCRas homolog family member C. (193 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (754 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
CLCA2Chloride channel accessory 2. (861 aa)
CLCA1Chloride channel accessory 1. (913 aa)
LOC100727821VWFA domain-containing protein. (923 aa)
LOC100726159VWFA domain-containing protein. (911 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (436 aa)
LOC100735470Uncharacterized protein. (296 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
LOC100717471Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (265 aa)
Bst1Uncharacterized protein. (288 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
H0VWZ0_CAVPOPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
PLA2G10Phospholipase A(2). (152 aa)
H0VX85_CAVPOUncharacterized protein. (184 aa)
Slc4a4Anion exchange protein. (1035 aa)
Chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
SCTSecretin; Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis. Exerts its biological effects by binding to secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells. Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content. Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the p [...] (162 aa)
H0W3H9_CAVPOPeptidase S1 domain-containing protein. (148 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa)
Fxyd2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
H0WB32_CAVPOSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (177 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
RAB11AUncharacterized protein. (216 aa)
LOC100732158Uncharacterized protein. (246 aa)
PLA2G2CPhospholipase A(2). (161 aa)
CCKCholecystokinin. (115 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (211 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
LOC100724525Alpha-amylase. (511 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa)
LOC100713271Uncharacterized protein. (165 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (252 aa)
CPA1Carboxypeptidase A1. (421 aa)
CPA4Carboxypeptidase A4. (421 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (348 aa)
ENSCPOP00000025593Uncharacterized protein. (180 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1048 aa)
GNAQG protein subunit alpha q. (313 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1133 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
RYR2Ryanodine receptor 2. (4910 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (306 aa)
ENSCPOP00000028762Uncharacterized protein. (107 aa)
ENSCPOP00000028852Phospholipase A(2). (146 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
SLC4A2Anion exchange protein 2; Plasma membrane anion exchange protein of wide distribution; Belongs to the anion exchanger (TC 2.A.31) family. (1268 aa)
PLA2G2FPhospholipase A(2). (214 aa)
ENSCPOP00000029947Phospholipase A(2). (146 aa)
LOC100715239Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1226 aa)
RHOARas homolog family member A. (193 aa)
LOC100732436Uncharacterized protein. (327 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
PLA2G5Phospholipase A(2). (138 aa)
Rap1bUncharacterized protein. (184 aa)
RAB27ARAB27A, member RAS oncogene family. (220 aa)
PLA2G1BPhospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family. (146 aa)
LOC100715518Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
CTRCChymotrypsin C; Belongs to the peptidase S1 family. (264 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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