STRINGSTRING
BAAT BAAT SCARB1 SCARB1 SCT SCT Baat Baat Slc4a4 Slc4a4 Ugt2b22 Ugt2b22 H0VW21_CAVPO H0VW21_CAVPO H0VVZ8_CAVPO H0VVZ8_CAVPO SLC25A39 SLC25A39 SLC51A SLC51A SCTR SCTR SLC22A6 SLC22A6 ABCC4 ABCC4 LOC100723442 LOC100723442 ADCY4 ADCY4 LOC100726998 LOC100726998 ADCY5 ADCY5 ABCC3 ABCC3 SLC22A7 SLC22A7 CFTR CFTR SLC4A5 SLC4A5 SLC27A5 SLC27A5 Aqp1 Aqp1 LOC100718313 LOC100718313 ABCC2 ABCC2 SLC9A5 SLC9A5 LOC100717542 LOC100717542 LOC106026682 LOC106026682 ADCY2 ADCY2 Atp1a3 Atp1a3 NR0B2 NR0B2 Ugt2b21 Ugt2b21 Slco1a2 Slco1a2 H0VE70_CAVPO H0VE70_CAVPO H0VC48_CAVPO H0VC48_CAVPO CA2 CA2 SLC22A8 SLC22A8 LOC100718591 LOC100718591 SLC5A4 SLC5A4 SLC5A1 SLC5A1 Slc22a20p Slc22a20p ADCY8 ADCY8 SLC9A3 SLC9A3 SLC10A1 SLC10A1 ABCB11 ABCB11 ADCY3 ADCY3 PTRHD1 PTRHD1 AQP8 AQP8 HMGCR HMGCR ATP1B3 ATP1B3 CYP7A1 CYP7A1 LOC100731507 LOC100731507 Std1 Std1 ADCY1 ADCY1 LOC100725815 LOC100725815 NR1H4 NR1H4 SLC10A2 SLC10A2 KCNN2 KCNN2 SLC2A1 SLC2A1 ABCG8 ABCG8 RXRA RXRA H0W482_CAVPO H0W482_CAVPO Prkaca Prkaca AQP9 AQP9 LOC100732436 LOC100732436 LOC100716350 LOC100716350 MINDY4 MINDY4 LOC100716581 LOC100716581 SLC4A2 SLC4A2 Std2 Std2 ATP1A2 ATP1A2 NCEH1 NCEH1 ATP1B1 ATP1B1 SLC9A1 SLC9A1 ADCY7 ADCY7 ADCY6 ADCY6 PRKACB PRKACB UGT1A6 UGT1A6 ATP1A1 ATP1A1 ADCY9 ADCY9 ATP1B4 ATP1B4 ENSCPOP00000025446 ENSCPOP00000025446 ATP1B2 ATP1B2 ATP1A4 ATP1A4 AQP4 AQP4 LOC100721490 LOC100721490 EPHX1 EPHX1 LOC100716628 LOC100716628 SLC25A40 SLC25A40 LOC100732684 LOC100732684 LOC100732158 LOC100732158 LDLR LDLR LOC100729579 LOC100729579 H0WB32_CAVPO H0WB32_CAVPO Fxyd2 Fxyd2 UGT2A3 UGT2A3 ABCG5 ABCG5 LOC100727060 LOC100727060 LOC100726785 LOC100726785 LOC100718030 LOC100718030 SLC51B SLC51B H0W664_CAVPO H0W664_CAVPO
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BAATBile acid-CoA:amino acid N-acyltransferase. (419 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
SCTSecretin; Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis. Exerts its biological effects by binding to secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells. Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content. Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the p [...] (162 aa)
BaatBile_Hydr_Trans domain-containing protein. (47 aa)
Slc4a4Anion exchange protein. (1035 aa)
Ugt2b22UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
H0VW21_CAVPOABC transporter domain-containing protein. (632 aa)
H0VVZ8_CAVPOABC transporter domain-containing protein. (662 aa)
SLC25A39Solute carrier family 25 member 39; Belongs to the mitochondrial carrier (TC 2.A.29) family. (351 aa)
SLC51ASolute carrier family 51 alpha subunit. (283 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (436 aa)
SLC22A6Solute carrier family 22 member 6. (545 aa)
ABCC4ATP binding cassette subfamily C member 4. (1324 aa)
LOC100723442ABC transporter domain-containing protein. (659 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
LOC100726998UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1032 aa)
ABCC3ATP binding cassette subfamily C member 3. (1523 aa)
SLC22A7Solute carrier family 22 member 7. (541 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
SLC4A5Anion exchange protein. (1118 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
Aqp1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
LOC100718313Solute carrier organic anion transporter family member. (608 aa)
ABCC2ATP binding cassette subfamily C member 2. (1537 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (799 aa)
LOC100717542UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (520 aa)
LOC106026682UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
Atp1a3Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (258 aa)
Ugt2b21UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
Slco1a2MFS domain-containing protein. (157 aa)
H0VE70_CAVPOUncharacterized protein. (796 aa)
H0VC48_CAVPOABC transporter domain-containing protein. (590 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (249 aa)
SLC22A8Solute carrier family 22 member 8. (538 aa)
LOC100718591Solute carrier organic anion transporter family member. (658 aa)
SLC5A4Solute carrier family 5 member 4; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (660 aa)
SLC5A1Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (661 aa)
Slc22a20pMFS domain-containing protein. (554 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (832 aa)
SLC10A1Solute carrier family 10 member 1. (285 aa)
ABCB11Uncharacterized protein. (1320 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (252 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known (By similarity); Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
CYP7A1Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (496 aa)
LOC100731507Sulfotransferase; Belongs to the sulfotransferase 1 family. (143 aa)
Std13-alpha-hydroxysteroid sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of 3-alpha- hydroxyl groups of neutral steroids. (288 aa)
ADCY1Adenylate cyclase 1. (944 aa)
LOC100725815UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (538 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (484 aa)
SLC10A2Solute carrier family 10 member 2. (349 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (842 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
ABCG8ATP binding cassette subfamily G member 8. (658 aa)
RXRARetinoid X receptor alpha. (459 aa)
H0W482_CAVPOUncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (645 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
LOC100732436Uncharacterized protein. (327 aa)
LOC100716350ABC transporter domain-containing protein. (658 aa)
MINDY4MINDY lysine 48 deubiquitinase 4. (779 aa)
LOC100716581ABC transporter domain-containing protein. (656 aa)
SLC4A2Anion exchange protein 2; Plasma membrane anion exchange protein of wide distribution; Belongs to the anion exchanger (TC 2.A.31) family. (1268 aa)
Std2Sulfotransferase; Belongs to the sulfotransferase 1 family. (268 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (408 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (306 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
UGT1A6UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (532 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1048 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (348 aa)
ENSCPOP00000025446Uncharacterized protein. (281 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (252 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
LOC100721490Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa)
EPHX1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (455 aa)
LOC100716628ABC transporter domain-containing protein. (658 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
LOC100732684Uncharacterized protein. (1219 aa)
LOC100732158Uncharacterized protein. (246 aa)
LDLRLow density lipoprotein receptor. (807 aa)
LOC100729579Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa)
H0WB32_CAVPOSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (177 aa)
Fxyd2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
UGT2A3UDP-glucuronosyltransferase 2A3; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). (530 aa)
ABCG5ATP binding cassette subfamily G member 5. (480 aa)
LOC100727060UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
LOC100726785UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (524 aa)
LOC100718030Solute carrier organic anion transporter family member. (682 aa)
SLC51BSolute carrier family 51 beta subunit. (120 aa)
H0W664_CAVPOUncharacterized protein. (1232 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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