STRINGSTRING
VDAC3 VDAC3 BCL2L1 BCL2L1 MAPK10 MAPK10 MFN2 MFN2 Prkaca Prkaca TXN2 TXN2 LOC100714158 LOC100714158 TUBB6 TUBB6 ATP5F1E ATP5F1E Psma2 Psma2 COX6B1 COX6B1 ENSCPOP00000032160 ENSCPOP00000032160 COX7B COX7B ENSCPOP00000032059 ENSCPOP00000032059 Ubc Ubc BAX BAX TRAP1 TRAP1 LOC100731649 LOC100731649 ENSCPOP00000031632 ENSCPOP00000031632 ENSCPOP00000031620 ENSCPOP00000031620 LOC100732436 LOC100732436 PSMC1 PSMC1 NDUFA4 NDUFA4 Atp5mc2 Atp5mc2 NDUFS2 NDUFS2 Ube2l3 Ube2l3 COX6A1 COX6A1 Septin5 Septin5 AKAP10 AKAP10 ATP5PD ATP5PD ADRM1 ADRM1 OSBPL2 OSBPL2 Camk2d Camk2d ITPR1 ITPR1 TUBB1 TUBB1 NDUFB4 NDUFB4 GNAI1 GNAI1 UBB UBB TP53 TP53 LOC100729187 LOC100729187 PSMA6 PSMA6 PSMB2 PSMB2 COX5A COX5A PSMD12 PSMD12 NDUFV2 NDUFV2 ENSCPOP00000029147 ENSCPOP00000029147 LOC100724240 LOC100724240 UBE2G1 UBE2G1 Vdac1 Vdac1 COX7A2 COX7A2 UQCRB UQCRB MAP3K5 MAP3K5 NDUFS5 NDUFS5 Ndufv3 Ndufv3 NFE2L2 NFE2L2 PSMD4 PSMD4 PSMD14 PSMD14 RYR3 RYR3 ENSCPOP00000027951 ENSCPOP00000027951 CALM3 CALM3 HTRA2 HTRA2 NDUFB10 NDUFB10 Sem1 Sem1 EIF2S1 EIF2S1 ATP5MC3 ATP5MC3 DUSP1 DUSP1 UQCRFS1 UQCRFS1 PRKACB PRKACB SNCA SNCA DAXX DAXX KIAA1958 KIAA1958 VDAC2 VDAC2 COX7A2L COX7A2L ENSCPOP00000025873 ENSCPOP00000025873 ENSCPOP00000025638 ENSCPOP00000025638 ENSCPOP00000025613 ENSCPOP00000025613 NDUFB5 NDUFB5 GNAI2 GNAI2 MFN1 MFN1 SNCAIP SNCAIP DRD1 DRD1 COX7C COX7C ENSCPOP00000025102 ENSCPOP00000025102 MAPK9 MAPK9 PSMD2 PSMD2 TUBB4A TUBB4A NDUFS7 NDUFS7 Ndufb8 Ndufb8 PSMC3 PSMC3 MAPK8 MAPK8 Atp5f1c Atp5f1c COX8A COX8A NDUFC1 NDUFC1 NDUFA5 NDUFA5 CALML4 CALML4 ENSCPOP00000023749 ENSCPOP00000023749 TUBB TUBB CAMK2G CAMK2G NDUFB3 NDUFB3 PSMA3 PSMA3 Ndufs4 Ndufs4 UBE2G2 UBE2G2 ENSCPOP00000022293 ENSCPOP00000022293 SDHC SDHC NDUFB6 NDUFB6 NDUFA4L2 NDUFA4L2 PSMD1 PSMD1 LOC100732158 LOC100732158 ATP5F1D ATP5F1D ADORA2A ADORA2A KLC4 KLC4 LOC100717486 LOC100717486 H0WDT2_CAVPO H0WDT2_CAVPO SLC6A3 SLC6A3 H0WAD6_CAVPO H0WAD6_CAVPO ITPR3 ITPR3 PSMB3 PSMB3 H0W813_CAVPO H0W813_CAVPO COX4I1 COX4I1 NDUFA8 NDUFA8 ARSI ARSI PSMA4 PSMA4 NDUFA13 NDUFA13 Psmd9 Psmd9 UQCRQ UQCRQ MRPL39 MRPL39 H0W3D2_CAVPO H0W3D2_CAVPO KLC1 KLC1 NDUFA3 NDUFA3 KIF5C KIF5C H0W2T6_CAVPO H0W2T6_CAVPO YJEFN3 YJEFN3 SDHB SDHB H0W1R6_CAVPO H0W1R6_CAVPO CAMK2B CAMK2B LOC100716197 LOC100716197 ATP5F1B ATP5F1B H0VZD4_CAVPO H0VZD4_CAVPO LOC100732987 LOC100732987 LOC100731885 LOC100731885 H0VXJ2_CAVPO H0VXJ2_CAVPO NDUFB2 NDUFB2 PLCG1 PLCG1 PSMC2 PSMC2 Ndufa11 Ndufa11 ATF4 ATF4 PINK1 PINK1 CYTB CYTB ND6 ND6 ND5 ND5 ND4 ND4 ND4L ND4L ND3 ND3 COX3 COX3 ATP6 ATP6 ATP8 ATP8 COX2 COX2 COX1 COX1 ND2 ND2 ND1 ND1 MCU MCU KLC3 KLC3 Txn Txn PSMA1 PSMA1 PSMB4 PSMB4 APAF1 APAF1 PSMD3 PSMD3 KLC2 KLC2 NDUFA6 NDUFA6 COX6C COX6C NDUFB7 NDUFB7 CALML3 CALML3 PSMA7 PSMA7 GPR37 GPR37 COX7A1 COX7A1 ATP5PB ATP5PB PSMB5 PSMB5 ADCY5 ADCY5 C7orf31 C7orf31 PSMA5 PSMA5 PPIF PPIF EIF2AK3 EIF2AK3 CYC1 CYC1 Mapt Mapt TUBA1B TUBA1B KIF5A KIF5A DDIT3 DDIT3 ATP5F1A ATP5F1A TH TH Hspa5 Hspa5 Casp3 Casp3 ITPR2 ITPR2 LOC100735918 LOC100735918 TUBB2B TUBB2B PSMA8 PSMA8 H0VKV0_CAVPO H0VKV0_CAVPO TUBB4B TUBB4B CASP9 CASP9 NDUFAB1 NDUFAB1 H0VJY6_CAVPO H0VJY6_CAVPO GNAI3 GNAI3 PSMC5 PSMC5 UQCR10 UQCR10 PSMD7 PSMD7 PSMD8 PSMD8 LOC100733352 LOC100733352 ATF6 ATF6 COX4I2 COX4I2 NDUFA9 NDUFA9 NDUFA12 NDUFA12 NDUFA10 NDUFA10 PSMD11 PSMD11 PSMC6 PSMC6 DRD2 DRD2 H0VE70_CAVPO H0VE70_CAVPO SLC25A5 SLC25A5 NDUFA2 NDUFA2 COX6B2 COX6B2 Atp5mc1 Atp5mc1 UBA7 UBA7 Sdha Sdha KIF5B KIF5B UBE2J2 UBE2J2 PSMB7 PSMB7 XBP1 XBP1 NDUFB9 NDUFB9 PARK7 PARK7 LOC100732718 LOC100732718 UQCRC2 UQCRC2 NDUFV1 NDUFV1 CAMK2A CAMK2A PSMD6 PSMD6 NDUFS3 NDUFS3 PRKN PRKN Rps27a Rps27a NDUFS1 NDUFS1 UBE2L6 UBE2L6 SLC25A4 SLC25A4 COX6A2 COX6A2 ATP5PF ATP5PF TUBA4A TUBA4A UQCRC1 UQCRC1 PSMC4 PSMC4 NDUFS6 NDUFS6 SLC18A2 SLC18A2 PSMD13 PSMD13 Sdhd Sdhd GNAL GNAL UBA1 UBA1 NDUFB11 NDUFB11 TUBA8 TUBA8 COX5B COX5B CALM1 CALM1 Ndufa7 Ndufa7 SLC25A31 SLC25A31 SLC18A1 SLC18A1 CALM2 CALM2 PSMB6 PSMB6 Ube2j1 Ube2j1 NDUFS8 NDUFS8 UCHL1 UCHL1 PSMB1 PSMB1 MAOA MAOA MAOB MAOB Atp5po Atp5po ERN1 ERN1 UBA52 UBA52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
VDAC3Voltage dependent anion channel 3. (283 aa)
BCL2L1BCL2 like 1. (233 aa)
MAPK10Mitogen-activated protein kinase 10. (434 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
TXN2Thioredoxin 2. (160 aa)
LOC100714158Uncharacterized protein. (70 aa)
TUBB6Tubulin beta 6 class V; Belongs to the tubulin family. (318 aa)
ATP5F1EATP synthase F1 subunit epsilon. (51 aa)
Psma2Proteasome subunit alpha type. (234 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
ENSCPOP00000032160Uncharacterized protein; Belongs to the heat shock protein 70 family. (609 aa)
COX7BCytochrome c oxidase subunit 7B. (80 aa)
ENSCPOP00000032059Uncharacterized protein; Belongs to the calmodulin family. (73 aa)
UbcUncharacterized protein. (159 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
TRAP1TNF receptor associated protein 1. (706 aa)
LOC100731649Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
ENSCPOP00000031620Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (297 aa)
LOC100732436Uncharacterized protein. (327 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (82 aa)
Atp5mc2ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
Ube2l3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (111 aa)
Septin5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa)
AKAP10A-kinase anchoring protein 10. (644 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
ADRM1Adhesion regulating molecule 1. (407 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (484 aa)
Camk2dProtein kinase domain-containing protein. (532 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (129 aa)
GNAI1Uncharacterized protein. (330 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa)
LOC100729187Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB2Proteasome subunit beta. (201 aa)
COX5ACytochrome c oxidase subunit 5A. (150 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (248 aa)
ENSCPOP00000029147Uncharacterized protein. (272 aa)
LOC100724240Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
Vdac1Uncharacterized protein. (283 aa)
COX7A2Cytochrome c oxidase subunit 7A2. (83 aa)
UQCRBCytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1344 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (106 aa)
Ndufv3Uncharacterized protein. (104 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (591 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
RYR3Ryanodine receptor 3. (4843 aa)
ENSCPOP00000027951Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (92 aa)
CALM3Calmodulin 3. (149 aa)
HTRA2HtrA serine peptidase 2. (455 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
Sem1Uncharacterized protein. (70 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
ATP5MC3Mitochondrial ATP synthase lipid-binding protein isoform A; Belongs to the ATPase C chain family. (141 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
DAXXDeath domain associated protein. (756 aa)
KIAA1958KIAA1958. (738 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
ENSCPOP00000025873Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (92 aa)
ENSCPOP00000025638Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
ENSCPOP00000025613Proton_antipo_M domain-containing protein. (171 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (189 aa)
GNAI2Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (737 aa)
SNCAIPSynuclein alpha interacting protein. (967 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (444 aa)
COX7CCytochrome c oxidase subunit 7C. (63 aa)
ENSCPOP00000025102Uncharacterized protein. (271 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (217 aa)
Ndufb8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
Atp5f1cATP synthase subunit gamma. (298 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (76 aa)
NDUFA5Uncharacterized protein. (116 aa)
CALML4Calmodulin like 4. (153 aa)
ENSCPOP00000023749Uncharacterized protein. (244 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (545 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (98 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
Ndufs4Uncharacterized protein. (175 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
ENSCPOP00000022293Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (459 aa)
SDHCSuccinate dehydrogenase complex subunit C. (169 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (128 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (87 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
LOC100732158Uncharacterized protein. (246 aa)
ATP5F1DATP synthase F1 subunit delta. (168 aa)
ADORA2AAdenosine receptor A2a; Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). (409 aa)
KLC4Kinesin light chain 4. (619 aa)
LOC100717486UBIQUITIN_CONJUGAT_2 domain-containing protein. (318 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa)
PSMB3Proteasome subunit beta. (207 aa)
H0W813_CAVPOUncharacterized protein. (753 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
ARSIArylsulfatase family member I. (572 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (140 aa)
Psmd9PDZ domain-containing protein. (223 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
MRPL39Mitochondrial ribosomal protein L39. (335 aa)
H0W3D2_CAVPOATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (122 aa)
KLC1Kinesin light chain 1. (616 aa)
NDUFA3NADH:ubiquinone oxidoreductase subunit A3. (84 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
H0W2T6_CAVPOUncharacterized protein. (189 aa)
YJEFN3YjeF N-terminal domain-containing protein. (228 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
H0W1R6_CAVPOThioredoxin; Belongs to the thioredoxin family. (106 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (659 aa)
LOC100716197Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (487 aa)
H0VZD4_CAVPOATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
LOC100732987Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
LOC100731885Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
H0VXJ2_CAVPOUncharacterized protein. (240 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (103 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
Ndufa11Uncharacterized protein. (142 aa)
ATF4Activating transcription factor 4. (354 aa)
PINK1PTEN induced kinase 1. (574 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (176 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (603 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
ATP6ATP synthase subunit a. (226 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (67 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (513 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (319 aa)
MCUMitochondrial calcium uniporter. (344 aa)
KLC3Kinesin light chain 3. (503 aa)
TxnThioredoxin; Belongs to the thioredoxin family. (105 aa)
PSMA1Proteasome subunit alpha type. (270 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
APAF1Apoptotic peptidase activating factor 1. (1265 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
KLC2Kinesin light chain 2. (622 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
COX6CCytochrome c oxidase subunit 6C. (75 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (131 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
GPR37G protein-coupled receptor 37. (606 aa)
COX7A1Cytochrome c oxidase subunit 7A1. (80 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
PSMB5Proteasome subunit beta. (263 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1032 aa)
C7orf31Chromosome 7 open reading frame 31. (591 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1112 aa)
CYC1Cytochrome c1. (327 aa)
MaptMicrotubule-associated protein. (370 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
DDIT3DNA damage inducible transcript 3. (167 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (527 aa)
THTyrosine hydroxylase. (498 aa)
Hspa5Uncharacterized protein; Belongs to the heat shock protein 70 family. (655 aa)
Casp3CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (165 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa)
LOC100735918NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
H0VKV0_CAVPOUncharacterized protein; Belongs to the calmodulin family. (139 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (447 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
H0VJY6_CAVPOThioredoxin domain-containing protein. (135 aa)
GNAI3Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] (354 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (64 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
LOC100733352Uncharacterized protein. (56 aa)
ATF6Activating transcription factor 6. (659 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (170 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
H0VE70_CAVPOUncharacterized protein. (796 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
COX6B2Cytochrome c oxidase subunit 6B2. (71 aa)
Atp5mc1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1003 aa)
SdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (652 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (929 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (271 aa)
PSMB7Proteasome subunit beta. (277 aa)
XBP1X-box binding protein 1. (268 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
LOC100732718Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (92 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (264 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (443 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (728 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (96 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (117 aa)
SLC18A2Solute carrier family 18 member A2. (516 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (315 aa)
SdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
GNALG protein subunit alpha L. (372 aa)
UBA1Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1058 aa)
NDUFB11Mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11 isoform 2. (153 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
COX5BCytochrome c oxidase subunit 5B. (129 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (194 aa)
Ndufa7Uncharacterized protein. (113 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
CALM2Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa)
PSMB6Proteasome subunit beta. (239 aa)
Ube2j1UBIQUITIN_CONJUGAT_2 domain-containing protein. (313 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (210 aa)
UCHL1Ubiquitin carboxyl-terminal hydrolase. (182 aa)
PSMB1Proteasome subunit beta. (241 aa)
MAOAAmine oxidase. (461 aa)
MAOBAmine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). (520 aa)
Atp5poUncharacterized protein. (219 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (974 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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