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| | EGFR | Receptor protein-tyrosine kinase. (1214 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (214 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (384 aa) |
| | PXN | Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (588 aa) |
| | PTGER4 | Prostaglandin E2 receptor 4; Belongs to the G-protein coupled receptor 1 family. (487 aa) |
| | CALR | Calreticulin. (417 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (481 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | LOC100713873 | Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa) |
| | Cxcr2 | Interleukin-8 receptor CXCR2; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | CALM2 | Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa) |
| | GNA12 | G protein subunit alpha 12. (315 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (604 aa) |
| | LOC100713317 | Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | CALM1 | Calmodulin 1; Belongs to the calmodulin family. (194 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa) |
| | ADCY1 | Adenylate cyclase 1. (944 aa) |
| | RHEBL1 | RHEB like 1. (183 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1494 aa) |
| | TSC2 | TSC complex subunit 2. (1745 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (928 aa) |
| | TSC1 | TSC complex subunit 1. (1166 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | GNB1 | Beta-transducin. (340 aa) |
| | PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (281 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) |
| | LOC100723960 | Ig-like domain-containing protein; Belongs to the MHC class I family. (453 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (967 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (531 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | RB1 | RB transcriptional corepressor 1. (840 aa) |
| | E2F2 | E2F transcription factor 2. (431 aa) |
| | CCL5 | C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family. (91 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | ELK1 | ETS transcription factor ELK1. (422 aa) |
| | H0VE70_CAVPO | Uncharacterized protein. (796 aa) |
| | Ifnb1 | Uncharacterized protein. (189 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (518 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (522 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (419 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1496 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (739 aa) |
| | Cgas | Mab-21 domain-containing protein. (387 aa) |
| | NRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) |
| | TRADD | TNFRSF1A associated via death domain. (310 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | Itgb3 | Integrin beta; Belongs to the integrin beta chain family. (735 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (206 aa) |
| | GNAI3 | Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] (354 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | LPXN | Leupaxin. (381 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (447 aa) |
| | H0VKV0_CAVPO | Uncharacterized protein; Belongs to the calmodulin family. (139 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa) |
| | Casp3 | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (165 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1371 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (916 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (325 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | CCL2 | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (120 aa) |
| | GNB5 | G protein subunit beta 5. (406 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (461 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (591 aa) |
| | RAC3 | Rac family small GTPase 3. (192 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1032 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (901 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (963 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (470 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | ATF4 | Activating transcription factor 4. (354 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (474 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity). (192 aa) |
| | H0VX22_CAVPO | C-C motif chemokine. (93 aa) |
| | IRF3 | Interferon regulatory factor 3. (389 aa) |
| | H0VYJ9_CAVPO | Uncharacterized protein. (1418 aa) |
| | LOC100734449 | Uncharacterized protein. (183 aa) |
| | TAP1 | Transporter 1, ATP binding cassette subfamily B member. (725 aa) |
| | GNB2 | G protein subunit beta 2. (378 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (549 aa) |
| | H0W027_CAVPO | Uncharacterized protein. (722 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (134 aa) |
| | CCR3 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (358 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | IL10RB | Interleukin 10 receptor subunit beta. (373 aa) |
| | H0W538_CAVPO | Uncharacterized protein. (315 aa) |
| | H0W5F0_CAVPO | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (187 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | H0W8W0_CAVPO | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | TAPBP | TAP binding protein. (436 aa) |
| | H0WBW4_CAVPO | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | LOC100735368 | C-C motif chemokine. (94 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa) |
| | GNA11 | G protein subunit alpha 11. (345 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | LOC100732158 | Uncharacterized protein. (246 aa) |
| | IL6R | Interleukin 6 receptor. (450 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (565 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity). (101 aa) |
| | Tap2 | Uncharacterized protein. (703 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (664 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1. (211 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1060 aa) |
| | PTGER2 | Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (125 aa) |
| | LOC100716398 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (392 aa) |
| | CALML4 | Calmodulin like 4. (153 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (484 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (385 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa) |
| | GNAO1 | G protein subunit alpha o1. (318 aa) |
| | PTGER1 | Prostaglandin E receptor 1. (405 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | ENSCPOP00000025638 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (169 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | ENSCPOP00000025873 | Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (92 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (583 aa) |
| | PTGER3 | Prostaglandin E receptor 3. (363 aa) |
| | Gng5 | G protein gamma domain-containing protein. (41 aa) |
| | E2F1 | E2F transcription factor 1. (389 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | LOC100717552 | C-C motif chemokine. (120 aa) |
| | Vegfa | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (186 aa) |
| | GNAQ | G protein subunit alpha q. (313 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | LOC106027640 | C-C motif chemokine. (97 aa) |
| | ATF6B | Activating transcription factor 6 beta. (694 aa) |
| | E2F3 | E2F transcription factor 3. (457 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (346 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (879 aa) |
| | LOC100733898 | Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | CALM3 | Calmodulin 3. (149 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | ENSCPOP00000027951 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (92 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (396 aa) |
| | ENSCPOP00000028708 | Uncharacterized protein. (153 aa) |
| | LOC100724240 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (469 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa) |
| | GNAI1 | Uncharacterized protein. (330 aa) |
| | LOC100734206 | Uncharacterized protein. (461 aa) |
| | LOC100724988 | Uncharacterized protein. (182 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (481 aa) |
| | RHEB | Uncharacterized protein. (184 aa) |
| | STING1 | Transmembrane protein 173. (379 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | ENSCPOP00000030509 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (388 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (572 aa) |
| | LOC100735187 | C-C motif chemokine. (93 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | FAS | Fas cell surface death receptor. (334 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | LOC100716672 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa) |
| | LOC100732436 | Uncharacterized protein. (327 aa) |
| | Arhgef1 | RGS-like domain-containing protein. (102 aa) |
| | Faslg | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (69 aa) |
| | ENSCPOP00000031524 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | LOC100731649 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | CSDE1 | Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa) |
| | PPP3R1 | Uncharacterized protein. (169 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (749 aa) |
| | ENSCPOP00000032059 | Uncharacterized protein; Belongs to the calmodulin family. (73 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | Prkaca | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) |
| | ENSCPOP00000033096 | DH domain-containing protein. (302 aa) |
