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BCL2L1 | BCL2 like 1. (233 aa) | ||||
MAPK10 | Mitogen-activated protein kinase 10. (434 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
ENSCPOP00000032616 | Ig-like domain-containing protein. (125 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (707 aa) | ||||
ENSCPOP00000032059 | Uncharacterized protein; Belongs to the calmodulin family. (73 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (749 aa) | ||||
PPP3R1 | Uncharacterized protein. (169 aa) | ||||
LOC100715212 | Uncharacterized protein. (482 aa) | ||||
CSDE1 | Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (192 aa) | ||||
LOC100731649 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
ENSCPOP00000031524 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa) | ||||
Faslg | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (69 aa) | ||||
LOC100716672 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa) | ||||
GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) | ||||
AP1M2 | AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (449 aa) | ||||
FBXW11 | F-box and WD repeat domain containing 11. (530 aa) | ||||
Ccnb1 | annotation not available (423 aa) | ||||
FAS | Fas cell surface death receptor. (334 aa) | ||||
ENSCPOP00000030888 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa) | ||||
ELOC | Elongin C; Belongs to the SKP1 family. (112 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa) | ||||
ENSCPOP00000030509 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) | ||||
STING1 | Transmembrane protein 173. (379 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (481 aa) | ||||
LOC100724988 | Uncharacterized protein. (182 aa) | ||||
LOC100734206 | Uncharacterized protein. (461 aa) | ||||
GNAI1 | Uncharacterized protein. (330 aa) | ||||
CFL2 | Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa) | ||||
CD247 | CD247 molecule. (164 aa) | ||||
ENSCPOP00000029477 | Ig-like domain-containing protein. (137 aa) | ||||
GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) | ||||
ENSCPOP00000029251 | Uncharacterized protein; Belongs to the SKP1 family. (147 aa) | ||||
ENSCPOP00000029129 | Protein kinase domain-containing protein. (254 aa) | ||||
AP1B1 | AP complex subunit beta. (945 aa) | ||||
ENSCPOP00000029012 | Uncharacterized protein. (138 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (469 aa) | ||||
LOC100724240 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
AP1S3 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa) | ||||
ENSCPOP00000028400 | Ig-like domain-containing protein. (116 aa) | ||||
ENSCPOP00000028279 | Ig-like domain-containing protein. (134 aa) | ||||
ENSCPOP00000027951 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (92 aa) | ||||
CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) | ||||
CALM3 | Calmodulin 3. (149 aa) | ||||
GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) | ||||
ENSCPOP00000027611 | Uncharacterized protein. (421 aa) | ||||
DDB1 | Damage specific DNA binding protein 1. (1140 aa) | ||||
LOC100733898 | Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa) | ||||
CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (346 aa) | ||||
CUL5 | Cullin 5; Belongs to the cullin family. (820 aa) | ||||
TRIM6 | Tripartite motif containing 6. (488 aa) | ||||
GNAQ | G protein subunit alpha q. (313 aa) | ||||
Gng5 | G protein gamma domain-containing protein. (41 aa) | ||||
TRBV19 | T cell receptor beta variable 19. (129 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) | ||||
GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
TRBV24-1 | T cell receptor beta variable 24-1. (133 aa) | ||||
AP1G1 | AP-1 complex subunit gamma. (734 aa) | ||||
ENSCPOP00000025873 | Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (92 aa) | ||||
ENSCPOP00000025638 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) | ||||
CUL4B | Cullin 4B; Belongs to the cullin family. (936 aa) | ||||
ENSCPOP00000025455 | Protein kinase domain-containing protein. (360 aa) | ||||
RBX1 | Ring-box 1. (108 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa) | ||||
GNB4 | G protein subunit beta 4. (340 aa) | ||||
GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
GNAO1 | G protein subunit alpha o1. (318 aa) | ||||
GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa) | ||||
CCDC194 | Coiled-coil domain containing 194. (185 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa) | ||||
RNF7 | Ring finger protein 7. (113 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (385 aa) | ||||
ENSCPOP00000024144 | Protein kinase domain-containing protein. (110 aa) | ||||
ENSCPOP00000024109 | DUF1968 domain-containing protein. (138 aa) | ||||
ENSCPOP00000023919 | Uncharacterized protein. (118 aa) | ||||
PAK3 | Non-specific serine/threonine protein kinase. (559 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (484 aa) | ||||
CALML4 | Calmodulin like 4. (153 aa) | ||||
B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (125 aa) | ||||
NFATC3 | Nuclear factor of activated T cells 3. (1060 aa) | ||||
GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) | ||||
Ccnb3 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (1277 aa) | ||||
PAK2 | Non-specific serine/threonine protein kinase. (524 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) | ||||
RAC1 | Ras-related C3 botulinum toxin substrate 1. (211 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (664 aa) | ||||
Tap2 | Uncharacterized protein. (703 aa) | ||||
TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (565 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
GNA11 | G protein subunit alpha 11. (345 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (253 aa) | ||||
H0WBW4_CAVPO | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) | ||||
TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (507 aa) | ||||
TAPBP | TAP binding protein. (436 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) | ||||
TLR2 | Toll like receptor 2; Belongs to the Toll-like receptor family. (782 aa) | ||||
H0W9P9_CAVPO | Wee1-like protein kinase. (551 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa) | ||||
Elob | Ubiquitin-like domain-containing protein. (118 aa) | ||||
PAK4 | Non-specific serine/threonine protein kinase. (592 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (294 aa) | ||||
AP1S2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa) | ||||
CD3G | CD3g molecule. (181 aa) | ||||
TNFRSF1B | TNF receptor superfamily member 1B. (482 aa) | ||||
H0W5F0_CAVPO | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (187 aa) | ||||
H0W538_CAVPO | Uncharacterized protein. (315 aa) | ||||
PAK6 | Non-specific serine/threonine protein kinase. (681 aa) | ||||
GNB3 | G protein subunit beta 3. (340 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (183 aa) | ||||
CCNB2 | Cyclin B2; Belongs to the cyclin family. (398 aa) | ||||
CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) | ||||
H0W0D3_CAVPO | Ig-like domain-containing protein. (126 aa) | ||||
H0W027_CAVPO | Uncharacterized protein. (722 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (549 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (459 aa) | ||||
GNB2 | G protein subunit beta 2. (378 aa) | ||||
TAP1 | Transporter 1, ATP binding cassette subfamily B member. (725 aa) | ||||
LOC100734449 | Uncharacterized protein. (183 aa) | ||||
IRF3 | Interferon regulatory factor 3. (389 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa) | ||||
CCDC125 | Coiled-coil domain containing 125. (543 aa) | ||||
LOC100720222 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (423 aa) | ||||
RAC2 | Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity). (192 aa) | ||||
Chek1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (439 aa) | ||||
CASP10 | Caspase 10; Belongs to the peptidase C14A family. (474 aa) | ||||
Wee2 | Wee1-like protein kinase. (557 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
AKT3 | AKT serine/threonine kinase 3. (470 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (837 aa) | ||||
TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (665 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
NFATC4 | Nuclear factor of activated T cells 4. (901 aa) | ||||
CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) | ||||
RAC3 | Rac family small GTPase 3. (192 aa) | ||||
C7orf31 | Chromosome 7 open reading frame 31. (591 aa) | ||||
AP1S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (182 aa) | ||||
GNB5 | G protein subunit beta 5. (406 aa) | ||||
CD3D | CD3d molecule. (171 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (325 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) | ||||
NFATC2 | Nuclear factor of activated T cells 2. (916 aa) | ||||
Casp3 | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (165 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa) | ||||
Cd4 | Uncharacterized protein. (523 aa) | ||||
H0VKV0_CAVPO | Uncharacterized protein; Belongs to the calmodulin family. (139 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (447 aa) | ||||
LPXN | Leupaxin. (381 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) | ||||
GNAI3 | Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] (354 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (206 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3031 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (310 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
NRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa) | ||||
H0VH94_CAVPO | Ig-like domain-containing protein. (123 aa) | ||||
Cgas | Mab-21 domain-containing protein. (387 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (739 aa) | ||||
GNG13 | G protein subunit gamma 13. (67 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (518 aa) | ||||
Ifnb1 | Uncharacterized protein. (189 aa) | ||||
LOC101787475 | Uncharacterized protein. (410 aa) | ||||
GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) | ||||
PDIA3 | Protein disulfide-isomerase. (505 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (531 aa) | ||||
SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (526 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (967 aa) | ||||
LOC100723960 | Ig-like domain-containing protein; Belongs to the MHC class I family. (453 aa) | ||||
CUL4A | Cullin 4A; Belongs to the cullin family. (759 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2539 aa) | ||||
Plvap | Uncharacterized protein. (421 aa) | ||||
CRK | CRK proto-oncogene, adaptor protein. (281 aa) | ||||
PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa) | ||||
DCAF1 | DDB1 and CUL4 associated factor 1. (1451 aa) | ||||
Bad | Uncharacterized protein. (166 aa) | ||||
GNB1 | Beta-transducin. (340 aa) | ||||
BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (582 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (314 aa) | ||||
Cdk1 | Protein kinase domain-containing protein. (240 aa) | ||||
SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (162 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa) | ||||
NFATC1 | Nuclear factor of activated T cells 1. (928 aa) | ||||
AP1M1 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (438 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa) | ||||
WEE1 | Wee1-like protein kinase. (612 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
PPP1R14B | Protein phosphatase 1 regulatory inhibitor subunit 14B. (108 aa) | ||||
LIMK2 | LIM domain kinase 2. (637 aa) | ||||
CALM1 | Calmodulin 1; Belongs to the calmodulin family. (194 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
LOC100713317 | Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa) | ||||
IRAK4 | Interleukin 1 receptor associated kinase 4. (462 aa) | ||||
CALM2 | Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa) | ||||
CD3E | CD3e molecule. (194 aa) | ||||
LOC100713873 | Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (214 aa) | ||||
MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (544 aa) | ||||
PXN | Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (588 aa) | ||||
AP1G2 | AP-1 complex subunit gamma. (786 aa) | ||||
LIMK1 | LIM domain kinase 1. (646 aa) | ||||
CALR | Calreticulin. (417 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa) | ||||
PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa) | ||||
PPP3CC | Serine/threonine-protein phosphatase. (481 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |