Your Input: | |||||
FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa) | ||||
Gstm2 | Glutathione S-transferase. (218 aa) | ||||
ARID2 | AT-rich interaction domain 2. (1763 aa) | ||||
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (390 aa) | ||||
NFE2L2 | Nuclear factor, erythroid 2 like 2. (591 aa) | ||||
DPF1 | Double PHD fingers 1. (367 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) | ||||
IGF2 | Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...] (237 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (738 aa) | ||||
BCL2L1 | BCL2 like 1. (233 aa) | ||||
KEAP1 | Kelch like ECH associated protein 1. (411 aa) | ||||
WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) | ||||
WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) | ||||
DPF3 | Double PHD fingers 3. (381 aa) | ||||
CSDE1 | Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa) | ||||
MGST1 | Microsomal glutathione S-transferase 1. (156 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (192 aa) | ||||
ENSCPOP00000027851 | Bromo domain-containing protein. (228 aa) | ||||
WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) | ||||
LOC100717598 | Uncharacterized protein; Belongs to the GST superfamily. (239 aa) | ||||
E2F3 | E2F transcription factor 3. (457 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (376 aa) | ||||
ARID1B | AT-rich interaction domain 1B. (1587 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
E2F1 | E2F transcription factor 1. (389 aa) | ||||
LOC100715394 | Uncharacterized protein; Belongs to the GST superfamily. (222 aa) | ||||
FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (596 aa) | ||||
WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (169 aa) | ||||
SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1201 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) | ||||
LOC100717315 | Uncharacterized protein. (240 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) | ||||
WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) | ||||
GSTM3 | Glutathione S-transferase mu 3; Belongs to the GST superfamily. (225 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (484 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (396 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
DVL3 | Dishevelled segment polarity protein 3. (717 aa) | ||||
TCF7L2 | Transcription factor 7 like 2. (350 aa) | ||||
ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa) | ||||
CSNK1A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa) | ||||
LOC100717041 | Uncharacterized protein; Belongs to the GST superfamily. (244 aa) | ||||
CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
GSTA1_CAVPO | Glutathione S-transferase A; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. (222 aa) | ||||
TCF7 | Transcription factor 7. (262 aa) | ||||
MGST2 | Microsomal glutathione S-transferase 2. (147 aa) | ||||
FRAT2 | FRAT regulator of WNT signaling pathway 2. (188 aa) | ||||
GSTT4 | Glutathione S-transferase theta 4; Belongs to the GST superfamily. (241 aa) | ||||
PHF10 | PHD finger protein 10. (482 aa) | ||||
HMOX1 | Heme oxygenase 1. (297 aa) | ||||
APC2 | APC regulator of WNT signaling pathway 2. (2086 aa) | ||||
GSTP1 | Glutathione S-transferase pi 1. (210 aa) | ||||
ACTL8 | Actin like 8; Belongs to the actin family. (371 aa) | ||||
ACTL9 | Actin like 9; Belongs to the actin family. (388 aa) | ||||
WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa) | ||||
SHC1 | SHC adaptor protein 1. (583 aa) | ||||
DVL2 | Dishevelled segment polarity protein 2. (737 aa) | ||||
LOC100731872 | Uncharacterized protein; Belongs to the actin family. (1226 aa) | ||||
FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (634 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa) | ||||
SHC3 | SHC adaptor protein 3. (418 aa) | ||||
ACTRT1 | Actin related protein T1; Belongs to the actin family. (377 aa) | ||||
ACTL7B | Actin like 7B; Belongs to the actin family. (412 aa) | ||||
LOC100723025 | Uncharacterized protein. (431 aa) | ||||
LOC100721187 | Uncharacterized protein. (489 aa) | ||||
CDKN2A | Cyclin dependent kinase inhibitor 2A. (134 aa) | ||||
H0W027_CAVPO | Uncharacterized protein. (722 aa) | ||||
FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa) | ||||
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (395 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) | ||||
ACTRT2 | Actin related protein T2; Belongs to the actin family. (376 aa) | ||||
H0VV76_CAVPO | Protein kinase domain-containing protein. (196 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1018 aa) | ||||
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1636 aa) | ||||
AKT3 | AKT serine/threonine kinase 3. (470 aa) | ||||
BRD7 | Bromodomain containing 7. (642 aa) | ||||
MGST3 | Microsomal glutathione S-transferase 3. (156 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa) | ||||
TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa) | ||||
WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa) | ||||
TCF7L1 | Transcription factor 7 like 1. (587 aa) | ||||
FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (538 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa) | ||||
MET | MET proto-oncogene, receptor tyrosine kinase. (1380 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
GADD45G | Growth arrest and DNA damage inducible gamma. (176 aa) | ||||
DDB2 | Damage specific DNA binding protein 2. (289 aa) | ||||
ARAF | A-Raf proto-oncogene, serine/threonine kinase. (608 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (325 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) | ||||
GSTO2 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa) | ||||
NQO1 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. (275 aa) | ||||
FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa) | ||||
GAB1 | GRB2 associated binding protein 1. (751 aa) | ||||
TXNRD1 | Thioredoxin reductase 1. (499 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) | ||||
SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (510 aa) | ||||
AXIN1 | Axin 1. (863 aa) | ||||
TXNRD2 | Uncharacterized protein. (524 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
NRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa) | ||||
ARID1A | AT-rich interaction domain 1A. (1903 aa) | ||||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1104 aa) | ||||
FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) | ||||
TGFA | Transforming growth factor alpha. (159 aa) | ||||
WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) | ||||
WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) | ||||
WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) | ||||
ELK1 | ETS transcription factor ELK1. (422 aa) | ||||
E2F2 | E2F transcription factor 2. (431 aa) | ||||
RB1 | RB transcriptional corepressor 1. (840 aa) | ||||
LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1600 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
GSTM1 | Glutathione S-transferase B; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. (222 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (440 aa) | ||||
TXNRD3 | Thioredoxin reductase 3. (612 aa) | ||||
DVL1 | Dishevelled segment polarity protein 1. (698 aa) | ||||
PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa) | ||||
Shc4 | Uncharacterized protein. (372 aa) | ||||
CEP152 | Centrosomal protein 152. (1666 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
ACTL7A | Actin like 7A; Belongs to the actin family. (440 aa) | ||||
Bad | Uncharacterized protein. (166 aa) | ||||
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1588 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
ACTL6B | Actin like 6B; Belongs to the actin family. (426 aa) | ||||
AXIN2 | Axin 2. (802 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
PPP1R14B | Protein phosphatase 1 regulatory inhibitor subunit 14B. (108 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa) | ||||
APC | APC regulator of WNT signaling pathway. (2842 aa) | ||||
TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
GSTO1 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. (239 aa) | ||||
POLK | DNA polymerase kappa. (540 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) | ||||
WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa) | ||||
PBRM1 | Polybromo 1. (1704 aa) | ||||
WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (396 aa) | ||||
SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (214 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1214 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) | ||||
WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
GADD45A | Growth arrest and DNA damage inducible alpha. (162 aa) | ||||
GSTA4 | Glutathione S-transferase alpha 4. (252 aa) | ||||
ACTG1 | Actin gamma 1. (375 aa) | ||||
GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) | ||||
LOC100734206 | Uncharacterized protein. (461 aa) | ||||
FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (505 aa) | ||||
FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |