Your Input: | |||||
Txn | Thioredoxin; Belongs to the thioredoxin family. (105 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
RHOC | Ras homolog family member C. (193 aa) | ||||
MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (386 aa) | ||||
CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) | ||||
RAC3 | Rac family small GTPase 3. (192 aa) | ||||
CCL2 | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (120 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) | ||||
GSTO2 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa) | ||||
NQO1 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. (275 aa) | ||||
SELE | Selectin E. (586 aa) | ||||
PECAM1 | Platelet and endothelial cell adhesion molecule 1. (743 aa) | ||||
H0VKV0_CAVPO | Uncharacterized protein; Belongs to the calmodulin family. (139 aa) | ||||
H0VJY6_CAVPO | Thioredoxin domain-containing protein. (135 aa) | ||||
Itgb3 | Integrin beta; Belongs to the integrin beta chain family. (735 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (739 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa) | ||||
PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) | ||||
CTSV | Cathepsin V; Belongs to the peptidase C1 family. (333 aa) | ||||
NCF2 | Neutrophil cytosolic factor 2. (513 aa) | ||||
SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (327 aa) | ||||
NCF1 | Neutrophil cytosolic factor 1. (401 aa) | ||||
GPC1 | Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa) | ||||
PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa) | ||||
GSTO1 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. (239 aa) | ||||
CALM2 | Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) | ||||
Hsp90aa1 | Heat shock protein 90 alpha family class A member 1. (733 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
PIAS4 | Protein inhibitor of activated STAT 4. (514 aa) | ||||
CALM1 | Calmodulin 1; Belongs to the calmodulin family. (194 aa) | ||||
HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (723 aa) | ||||
NOS3 | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity); Belongs to the NOS family. (1206 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) | ||||
ACTL7A | Actin like 7A; Belongs to the actin family. (440 aa) | ||||
PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa) | ||||
VCAM1 | Vascular cell adhesion molecule 1. (732 aa) | ||||
ITGA2B | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1007 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (404 aa) | ||||
MMP9 | Matrix metallopeptidase 9. (715 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (967 aa) | ||||
GSTM1 | Glutathione S-transferase B; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. (222 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (489 aa) | ||||
ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa) | ||||
MAPK10 | Mitogen-activated protein kinase 10. (434 aa) | ||||
KEAP1 | Kelch like ECH associated protein 1. (411 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
TXN2 | Thioredoxin 2. (160 aa) | ||||
IL1R2 | Interleukin 1 receptor type 2. (440 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (190 aa) | ||||
ENSCPOP00000032444 | annotation not available (74 aa) | ||||
SDC2 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa) | ||||
ENSCPOP00000032059 | Uncharacterized protein; Belongs to the calmodulin family. (73 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (749 aa) | ||||
MGST1 | Microsomal glutathione S-transferase 1. (156 aa) | ||||
SUMO4 | Small ubiquitin-related modifier. (81 aa) | ||||
MEF2A | Myocyte enhancer factor 2A. (517 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (747 aa) | ||||
GSTA4 | Glutathione S-transferase alpha 4. (252 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa) | ||||
ACTG1 | Actin gamma 1. (375 aa) | ||||
IL1R1 | Interleukin 1 receptor type 1. (572 aa) | ||||
LOC100734206 | Uncharacterized protein. (461 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa) | ||||
Gstm2 | Glutathione S-transferase. (218 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (469 aa) | ||||
EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (208 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1344 aa) | ||||
NFE2L2 | Nuclear factor, erythroid 2 like 2. (591 aa) | ||||
HSP90B1 | Heat shock protein 90 beta family member 1. (807 aa) | ||||
SUMO1 | Small ubiquitin-related modifier. (101 aa) | ||||
CALM3 | Calmodulin 3. (149 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) | ||||
TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa) | ||||
LOC100717598 | Uncharacterized protein; Belongs to the GST superfamily. (239 aa) | ||||
SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa) | ||||
Cav2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (125 aa) | ||||
LOC106027640 | C-C motif chemokine. (97 aa) | ||||
ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa) | ||||
DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa) | ||||
Vegfa | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (186 aa) | ||||
LOC100717552 | C-C motif chemokine. (120 aa) | ||||
LOC100715394 | Uncharacterized protein; Belongs to the GST superfamily. (222 aa) | ||||
Sumo2 | Small ubiquitin-related modifier. (95 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
ENSCPOP00000024881 | Rad60-SLD domain-containing protein. (74 aa) | ||||
LOC100717315 | Uncharacterized protein. (240 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (385 aa) | ||||
NOX1 | NADPH oxidase 1. (564 aa) | ||||
GSTM3 | Glutathione S-transferase mu 3; Belongs to the GST superfamily. (225 aa) | ||||
CALML4 | Calmodulin like 4. (153 aa) | ||||
SQSTM1 | Sequestosome 1. (415 aa) | ||||
BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa) | ||||
LOC100725824 | HATPase_c domain-containing protein. (695 aa) | ||||
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (986 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
RAC1 | Ras-related C3 botulinum toxin substrate 1. (211 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
MEF2C | Myocyte enhancer factor 2C. (483 aa) | ||||
ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) | ||||
LOC100717041 | Uncharacterized protein; Belongs to the GST superfamily. (244 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
GSTA1_CAVPO | Glutathione S-transferase A; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. (222 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (253 aa) | ||||
MGST2 | Microsomal glutathione S-transferase 2. (147 aa) | ||||
ASS1 | Argininosuccinate synthase 1. (415 aa) | ||||
GSTT4 | Glutathione S-transferase theta 4; Belongs to the GST superfamily. (241 aa) | ||||
H0WCB2_CAVPO | Uncharacterized protein. (418 aa) | ||||
MMP2 | Matrix metallopeptidase 2. (662 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) | ||||
HMOX1 | Heme oxygenase 1. (297 aa) | ||||
MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (797 aa) | ||||
GSTP1 | Glutathione S-transferase pi 1. (210 aa) | ||||
THBD | Thrombomodulin. (534 aa) | ||||
ACTL8 | Actin like 8; Belongs to the actin family. (371 aa) | ||||
ACTL9 | Actin like 9; Belongs to the actin family. (388 aa) | ||||
BMPR1A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa) | ||||
LOC100731872 | Uncharacterized protein; Belongs to the actin family. (1226 aa) | ||||
NPPC | Natriuretic peptide C. (126 aa) | ||||
ACTRT1 | Actin related protein T1; Belongs to the actin family. (377 aa) | ||||
ACTL7B | Actin like 7B; Belongs to the actin family. (412 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (183 aa) | ||||
IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). (272 aa) | ||||
H0W1R6_CAVPO | Thioredoxin; Belongs to the thioredoxin family. (106 aa) | ||||
PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (559 aa) | ||||
H0W027_CAVPO | Uncharacterized protein. (722 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (549 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (459 aa) | ||||
CYBA | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (189 aa) | ||||
SUMO3 | Small ubiquitin-related modifier. (109 aa) | ||||
ACTRT2 | Actin related protein T2; Belongs to the actin family. (376 aa) | ||||
RAC2 | Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity). (192 aa) | ||||
AKT3 | AKT serine/threonine kinase 3. (470 aa) | ||||
ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (963 aa) | ||||
MGST3 | Microsomal glutathione S-transferase 3. (156 aa) |