25 items (Heterocephalus glaber) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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Your Input:
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	GW7_07296	Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (464 aa)
	AMACR	Alpha-methylacyl-CoA racemase isoform 2. (382 aa)
	GW7_19175	24-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (488 aa)
	Atp8b1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1257 aa)
	Akr1d1	3-oxo-5-beta-steroid 4-dehydrogenase. (175 aa)
	Nr1h4	Bile acid receptor. (487 aa)
	HSD17B10	3-hydroxyacyl-CoA dehydrogenase type-2 isoform 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
	Scp2	Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (521 aa)
	GW7_06333	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (414 aa)
	Slc27a5	Bile acyl-CoA synthetase. (690 aa)
	GW7_12896	Nuclear receptor subfamily 5 group A member 2. (410 aa)
	GW7_07439	25-hydroxycholesterol 7-alpha-hydroxylase. (466 aa)
	HNF1A	Hepatocyte nuclear factor 1-alpha. (631 aa)
	Abcd3	ATP-binding cassette sub-family D member 3. (621 aa)
	GW7_07365	3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	GW7_06937	3-oxo-5-beta-steroid 4-dehydrogenase. (133 aa)
	GW7_09255	Bile acid-CoA:amino acid N-acyltransferase. (230 aa)
	GW7_00819	Protein ARV1. (135 aa)
	Nr5a2	Nuclear receptor subfamily 5 group A member 2. (391 aa)
	BAAT	Bile acid-CoA:amino acid N-acyltransferase. (420 aa)
	PEX2	Peroxisomal biogenesis factor 2. (305 aa)
	GW7_16245	3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
	ABCB11	Bile salt export pump. (1321 aa)
	GW7_17721	Bile acid-CoA:amino acid N-acyltransferase. (177 aa)

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB11	Atp8b1	G5C8Q9	G5BCD1	Bile salt export pump.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.488
ABCB11	GW7_06333	G5C8Q9	G5B704	Bile salt export pump.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.607
ABCB11	Nr1h4	G5C8Q9	G5BBI4	Bile salt export pump.	Bile acid receptor.	0.636
ABCB11	Slc27a5	G5C8Q9	G5B3G7	Bile salt export pump.	Bile acyl-CoA synthetase.	0.543
AMACR	Akr1d1	G5BQ98	G5BC85	Alpha-methylacyl-CoA racemase isoform 2.	3-oxo-5-beta-steroid 4-dehydrogenase.	0.537
AMACR	BAAT	G5BQ98	G5BTN9	Alpha-methylacyl-CoA racemase isoform 2.	Bile acid-CoA:amino acid N-acyltransferase.	0.647
AMACR	GW7_07365	G5BQ98	G5ATL7	Alpha-methylacyl-CoA racemase isoform 2.	3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.	0.531
AMACR	GW7_16245	G5BQ98	G5C5P5	Alpha-methylacyl-CoA racemase isoform 2.	3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.	0.531
AMACR	Scp2	G5BQ98	G5BAL6	Alpha-methylacyl-CoA racemase isoform 2.	Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.852
AMACR	Slc27a5	G5BQ98	G5B3G7	Alpha-methylacyl-CoA racemase isoform 2.	Bile acyl-CoA synthetase.	0.944
Abcd3	PEX2	G5AW28	G5BUW0	ATP-binding cassette sub-family D member 3.	Peroxisomal biogenesis factor 2.	0.745
Abcd3	Scp2	G5AW28	G5BAL6	ATP-binding cassette sub-family D member 3.	Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.722
Akr1d1	AMACR	G5BC85	G5BQ98	3-oxo-5-beta-steroid 4-dehydrogenase.	Alpha-methylacyl-CoA racemase isoform 2.	0.537
Akr1d1	BAAT	G5BC85	G5BTN9	3-oxo-5-beta-steroid 4-dehydrogenase.	Bile acid-CoA:amino acid N-acyltransferase.	0.495
Akr1d1	GW7_06937	G5BC85	G5ARQ2	3-oxo-5-beta-steroid 4-dehydrogenase.	3-oxo-5-beta-steroid 4-dehydrogenase.	0.536
Akr1d1	Slc27a5	G5BC85	G5B3G7	3-oxo-5-beta-steroid 4-dehydrogenase.	Bile acyl-CoA synthetase.	0.582
Atp8b1	ABCB11	G5BCD1	G5C8Q9	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Bile salt export pump.	0.488
BAAT	AMACR	G5BTN9	G5BQ98	Bile acid-CoA:amino acid N-acyltransferase.	Alpha-methylacyl-CoA racemase isoform 2.	0.647
BAAT	Akr1d1	G5BTN9	G5BC85	Bile acid-CoA:amino acid N-acyltransferase.	3-oxo-5-beta-steroid 4-dehydrogenase.	0.495
BAAT	GW7_09255	G5BTN9	G5ANC1	Bile acid-CoA:amino acid N-acyltransferase.	Bile acid-CoA:amino acid N-acyltransferase.	0.900