(35 nodes) Collagen catabolic process network (Heterocephalus glaber)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mmp28	Matrix metalloproteinase-28. (525 aa)
	Fam134a	Protein FAM134A. (462 aa)
	GW7_12804	Cathepsin L1; Belongs to the peptidase C1 family. (278 aa)
	CTSB	Cathepsin B preproprotein; Belongs to the peptidase C1 family. (340 aa)
	Mmp14	Matrix metalloproteinase-14. (561 aa)
	Mmp23b	Matrix metalloproteinase-23. (154 aa)
	GW7_12015	Matrix metalloproteinase-15. (714 aa)
	GW7_03173	Matrix metalloproteinase-17. (800 aa)
	Fam134c	Protein FAM134C. (404 aa)
	Fam134b	Protein FAM134B. (400 aa)
	Mmp25	Matrix metalloproteinase-25. (581 aa)
	GW7_13880	Cathepsin L1; Belongs to the peptidase C1 family. (239 aa)
	Mmp11	Stromelysin-3. (453 aa)
	Mmp9	Matrix metalloproteinase-9. (699 aa)
	MMP19	Matrix metalloproteinase-19 isoform rasi-1 preproprotein. (522 aa)
	Mrc2	C-type mannose receptor 2. (1390 aa)
	GW7_05378	Protein FAM134B. (203 aa)
	GW7_17654	Protein FAM134B. (203 aa)
	Ctss	Cathepsin S; Belongs to the peptidase C1 family. (331 aa)
	GW7_17474	Matrix metalloproteinase-16. (561 aa)
	Mmp2	72 kDa type IV collagenase. (662 aa)
	Mmp7	Matrilysin. (265 aa)
	Mmp20	Matrix metalloproteinase-20. (483 aa)
	Mmp27	Matrix metalloproteinase-27. (511 aa)
	MMP8	Neutrophil collagenase preproprotein. (470 aa)
	Mmp10	Stromelysin-2. (475 aa)
	Mmp1	Interstitial collagenase. (446 aa)
	Mmp3	Stromelysin-1. (471 aa)
	Mmp12	Macrophage metalloelastase. (403 aa)
	Mmp13	Collagenase 3. (471 aa)
	Pepd	Xaa-Pro dipeptidase. (487 aa)
	GW7_14930	Cathepsin L1; Belongs to the peptidase C1 family. (278 aa)
	GW7_21540	Matrix metalloproteinase-24. (492 aa)
	Mmp21	Matrix metalloproteinase-21. (567 aa)
	Ctsk	Cathepsin K; Belongs to the peptidase C1 family. (329 aa)

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTSB	Ctsk	G5AMF3	G5AJX8	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	Cathepsin K; Belongs to the peptidase C1 family.	0.498
CTSB	Ctss	G5AMF3	G5BH45	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	Cathepsin S; Belongs to the peptidase C1 family.	0.956
CTSB	GW7_12804	G5AMF3	G5ALK3	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	Cathepsin L1; Belongs to the peptidase C1 family.	0.953
CTSB	GW7_13880	G5AMF3	G5B5H8	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	Cathepsin L1; Belongs to the peptidase C1 family.	0.526
CTSB	GW7_14930	G5AMF3	G5C0M2	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	Cathepsin L1; Belongs to the peptidase C1 family.	0.518
CTSB	Mmp12	G5AMF3	G5BUC6	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	Macrophage metalloelastase.	0.451
CTSB	Mmp9	G5AMF3	G5B7Q1	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	Matrix metalloproteinase-9.	0.563
Ctsk	CTSB	G5AJX8	G5AMF3	Cathepsin K; Belongs to the peptidase C1 family.	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	0.498
Ctsk	MMP8	G5AJX8	G5BUC2	Cathepsin K; Belongs to the peptidase C1 family.	Neutrophil collagenase preproprotein.	0.461
Ctsk	Mmp13	G5AJX8	G5BUC9	Cathepsin K; Belongs to the peptidase C1 family.	Collagenase 3.	0.679
Ctsk	Mmp7	G5AJX8	G5BUB9	Cathepsin K; Belongs to the peptidase C1 family.	Matrilysin.	0.584
Ctsk	Mmp9	G5AJX8	G5B7Q1	Cathepsin K; Belongs to the peptidase C1 family.	Matrix metalloproteinase-9.	0.650
Ctss	CTSB	G5BH45	G5AMF3	Cathepsin S; Belongs to the peptidase C1 family.	Cathepsin B preproprotein; Belongs to the peptidase C1 family.	0.956
Ctss	GW7_12804	G5BH45	G5ALK3	Cathepsin S; Belongs to the peptidase C1 family.	Cathepsin L1; Belongs to the peptidase C1 family.	0.929
Ctss	Mmp12	G5BH45	G5BUC6	Cathepsin S; Belongs to the peptidase C1 family.	Macrophage metalloelastase.	0.513
Ctss	Mmp13	G5BH45	G5BUC9	Cathepsin S; Belongs to the peptidase C1 family.	Collagenase 3.	0.563
Ctss	Mmp2	G5BH45	G5BSD7	Cathepsin S; Belongs to the peptidase C1 family.	72 kDa type IV collagenase.	0.403
Ctss	Mmp7	G5BH45	G5BUB9	Cathepsin S; Belongs to the peptidase C1 family.	Matrilysin.	0.540
Ctss	Mmp9	G5BH45	G5B7Q1	Cathepsin S; Belongs to the peptidase C1 family.	Matrix metalloproteinase-9.	0.490
GW7_03173	Mmp13	G5AWQ0	G5BUC9	Matrix metalloproteinase-17.	Collagenase 3.	0.494