STRINGSTRING
GW7_08559 GW7_08559 Cdc73 Cdc73 MED18 MED18 DAB2 DAB2 Map2k1 Map2k1 GW7_04507 GW7_04507 Ctnnb1 Ctnnb1 GW7_10179 GW7_10179 MED8 MED8 GW7_02181 GW7_02181 Pwwp2a Pwwp2a Pwwp2b Pwwp2b SUPT16H SUPT16H GW7_17177 GW7_17177 CDK9 CDK9 GW7_18776 GW7_18776 CDK12 CDK12 GW7_13466 GW7_13466 Ell2 Ell2 Supt6h Supt6h Brd4 Brd4 GW7_05772 GW7_05772 GW7_02170 GW7_02170 GW7_04998 GW7_04998 GW7_15276 GW7_15276 Leo1 Leo1 GW7_09875 GW7_09875 GW7_16199 GW7_16199 Ikzf1 Ikzf1 Ell Ell GW7_02593 GW7_02593 GW7_17744 GW7_17744 Ccnt1 Ccnt1 Med30 Med30
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GW7_08559RNA polymerase II elongation factor ELL2. (375 aa)
Cdc73Parafibromin. (533 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
DAB2Disabled homolog 2 isoform 2. (769 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
GW7_04507Cyclin-T2. (526 aa)
Ctnnb1Catenin beta-1. (944 aa)
GW7_10179Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (327 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (276 aa)
GW7_02181RNA polymerase II elongation factor ELL2. (260 aa)
Pwwp2aPWWP domain-containing protein 2A. (242 aa)
Pwwp2bPWWP domain-containing protein 2B. (583 aa)
SUPT16HFACT complex subunit SPT16. (1047 aa)
GW7_17177E2F-associated phosphoprotein. (378 aa)
CDK9Cell division protein kinase 9; Belongs to the protein kinase superfamily. (372 aa)
GW7_18776RNA polymerase II elongation factor ELL3. (392 aa)
CDK12Cell division cycle 2-related protein kinase 7. (1489 aa)
GW7_13466Parafibromin. (451 aa)
Ell2RNA polymerase II elongation factor ELL2. (575 aa)
Supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1738 aa)
Brd4Bromodomain-containing protein 4. (1225 aa)
GW7_05772Cyclin-T2; Belongs to the cyclin family. (593 aa)
GW7_02170Dual specificity mitogen-activated protein kinase kinase 1. (189 aa)
GW7_04998Cyclin-T1. (297 aa)
GW7_15276Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (513 aa)
Leo1RNA polymerase-associated protein LEO1. (665 aa)
GW7_09875Cell division cycle 2-like protein kinase 5. (1067 aa)
GW7_16199Cyclin-K; Belongs to the cyclin family. (573 aa)
Ikzf1DNA-binding protein Ikaros. (500 aa)
EllRNA polymerase II elongation factor ELL. (557 aa)
GW7_02593Chromobox protein-like protein 7. (299 aa)
GW7_17744Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (384 aa)
Ccnt1Cyclin-T1; Belongs to the cyclin family. (711 aa)
Med30Mediator of RNA polymerase II transcription subunit 30. (178 aa)
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.