STRINGSTRING
GW7_02490 GW7_02490 GW7_03627 GW7_03627 GW7_15411 GW7_15411 Homer1 Homer1 Cdk5 Cdk5 GW7_03611 GW7_03611 Parp1 Parp1 GW7_14531 GW7_14531 Ehmt2 Ehmt2 Snca Snca Fadd Fadd Abat Abat Ppp1r1b Ppp1r1b Drd1 Drd1 Crhr1 Crhr1 GW7_16872 GW7_16872 Homer2 Homer2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GW7_02490D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (437 aa)
GW7_03627CREB-binding protein. (2098 aa)
GW7_15411Homer protein-like protein 2. (334 aa)
Homer1Homer protein-like protein 1. (352 aa)
Cdk5Cell division protein kinase 5; Belongs to the protein kinase superfamily. (299 aa)
GW7_03611D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (400 aa)
Parp1Poly [ADP-ribose] polymerase. (1132 aa)
GW7_14531CREB-binding protein. (483 aa)
Ehmt2Histone-lysine N-methyltransferase, H3 lysine-9 specific 3. (1329 aa)
SncaAlpha-synuclein; Belongs to the synuclein family. (121 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (197 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (477 aa)
Ppp1r1bProtein phosphatase 1 regulatory subunit 1B. (291 aa)
Drd1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (438 aa)
Crhr1Corticotropin-releasing factor receptor 1; Belongs to the G-protein coupled receptor 2 family. (417 aa)
GW7_16872Protein sidekick-1. (2325 aa)
Homer2Homer protein-like protein 2. (348 aa)
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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