(32 nodes) Positive regulation of cartilage development network (Heterocephalus glaber)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	GW7_21277	Growth/differentiation factor 5. (452 aa)
	GW7_16534	Mothers against decapentaplegic homolog. (373 aa)
	GW7_20726	Metalloendopeptidase. (1586 aa)
	Loxl2	Lysyl oxidase-like protein 2. (782 aa)
	GW7_06451	Bone morphogenetic protein 6. (562 aa)
	GW7_01119	Homeobox protein Hox-A11b. (324 aa)
	Sox5	Transcription factor SOX-5. (485 aa)
	GW7_00198	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	Bmp4	Bone morphogenetic protein 4. (409 aa)
	Thrb	Thyroid hormone receptor beta. (476 aa)
	Znf219	Zinc finger protein 219. (717 aa)
	GW7_19170	Runt-related transcription factor 2. (595 aa)
	BMP10	Bone morphogenetic protein 10 preproprotein. (424 aa)
	GW7_09940	Fibroblast growth factor 18. (106 aa)
	GW7_01173	Midkine. (137 aa)
	Pkdcc	Kinase-like protein SgK493. (340 aa)
	Sox6	Transcription factor SOX-6. (680 aa)
	GW7_14874	Transcription factor SOX-6. (110 aa)
	Bmp2	Bone morphogenetic protein 2. (397 aa)
	GW7_10524	Mothers against decapentaplegic homolog. (415 aa)
	GW7_04146	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1257 aa)
	GW7_06989	Mothers against decapentaplegic-like protein 1. (378 aa)
	Smad3	Mothers against decapentaplegic homolog. (409 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	Cyr61	Protein CYR61. (381 aa)
	GW7_12752	Growth/differentiation factor 2. (153 aa)
	Sox9	Transcription factor SOX-9. (507 aa)
	GW7_07238	Growth/differentiation factor 2. (433 aa)
	GW7_06011	Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (403 aa)
	Gli3	Zinc finger protein GLI3. (1425 aa)
	GW7_19860	Mothers against decapentaplegic homolog. (394 aa)
	Zbtb16	Zinc finger and BTB domain-containing protein 16. (684 aa)

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	GW7_04146	G5BNY7	G5C1S5	Bone morphogenetic protein 10 preproprotein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.928
BMP10	GW7_07238	G5BNY7	G5AZY9	Bone morphogenetic protein 10 preproprotein.	Growth/differentiation factor 2.	0.627
BMP10	GW7_12752	G5BNY7	G5CAC1	Bone morphogenetic protein 10 preproprotein.	Growth/differentiation factor 2.	0.627
Bmp2	Bmp4	G5C098	G5BF86	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.940
Bmp2	GW7_04146	G5C098	G5C1S5	Bone morphogenetic protein 2.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.934
Bmp2	GW7_06451	G5C098	G5BAT6	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.637
Bmp2	GW7_06989	G5C098	G5C2B0	Bone morphogenetic protein 2.	Mothers against decapentaplegic-like protein 1.	0.489
Bmp2	GW7_10524	G5C098	G5C0F3	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.489
Bmp2	GW7_16534	G5C098	G5B879	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.640
Bmp2	GW7_19170	G5C098	G5BNF2	Bone morphogenetic protein 2.	Runt-related transcription factor 2.	0.662
Bmp2	GW7_19860	G5C098	G5B7D9	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.489
Bmp2	GW7_20726	G5C098	G5B9Q0	Bone morphogenetic protein 2.	Metalloendopeptidase.	0.506
Bmp2	GW7_21277	G5C098	G5B852	Bone morphogenetic protein 2.	Growth/differentiation factor 5.	0.637
Bmp2	SMAD1	G5C098	G5C7E2	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.489
Bmp2	Smad3	G5C098	G5C5G2	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.494
Bmp4	Bmp2	G5BF86	G5C098	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.940
Bmp4	GW7_04146	G5BF86	G5C1S5	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.910
Bmp4	GW7_06451	G5BF86	G5BAT6	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.637
Bmp4	GW7_06989	G5BF86	G5C2B0	Bone morphogenetic protein 4.	Mothers against decapentaplegic-like protein 1.	0.522
Bmp4	GW7_10524	G5BF86	G5C0F3	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.522