(12 nodes) Phosphorylation of RNA polymerase II C-terminal domain network (Heterocephalus glaber)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GTF2H1	General transcription factor IIH subunit 1. (548 aa)
	GW7_16199	Cyclin-K; Belongs to the cyclin family. (573 aa)
	CDK9	Cell division protein kinase 9; Belongs to the protein kinase superfamily. (372 aa)
	GW7_09875	Cell division cycle 2-like protein kinase 5. (1067 aa)
	Cdk7	Cell division protein kinase 7. (281 aa)
	GW7_04998	Cyclin-T1. (297 aa)
	Gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
	Gtf2h3	General transcription factor IIH subunit 3. (89 aa)
	CDK12	Cell division cycle 2-related protein kinase 7. (1489 aa)
	GW7_03149	General transcription factor IIH subunit 3. (315 aa)
	Ccnt1	Cyclin-T1; Belongs to the cyclin family. (711 aa)
	CCNH	Cyclin-H isoform 1; Belongs to the cyclin family. (323 aa)

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNH	CDK12	G5AT77	G5BRW7	Cyclin-H isoform 1; Belongs to the cyclin family.	Cell division cycle 2-related protein kinase 7.	0.781
CCNH	CDK9	G5AT77	G5BLG4	Cyclin-H isoform 1; Belongs to the cyclin family.	Cell division protein kinase 9; Belongs to the protein kinase superfamily.	0.728
CCNH	Ccnt1	G5AT77	G5AU45	Cyclin-H isoform 1; Belongs to the cyclin family.	Cyclin-T1; Belongs to the cyclin family.	0.644
CCNH	Cdk7	G5AT77	G5B4C7	Cyclin-H isoform 1; Belongs to the cyclin family.	Cell division protein kinase 7.	0.999
CCNH	GTF2H1	G5AT77	G5AKA4	Cyclin-H isoform 1; Belongs to the cyclin family.	General transcription factor IIH subunit 1.	0.995
CCNH	GW7_03149	G5AT77	G5AWT8	Cyclin-H isoform 1; Belongs to the cyclin family.	General transcription factor IIH subunit 3.	0.977
CCNH	GW7_04998	G5AT77	G5C3W4	Cyclin-H isoform 1; Belongs to the cyclin family.	Cyclin-T1.	0.644
CCNH	GW7_09875	G5AT77	G5B6U5	Cyclin-H isoform 1; Belongs to the cyclin family.	Cell division cycle 2-like protein kinase 5.	0.781
CCNH	GW7_16199	G5AT77	G5B4A6	Cyclin-H isoform 1; Belongs to the cyclin family.	Cyclin-K; Belongs to the cyclin family.	0.895
CCNH	Gtf2h3	G5AT77	G5C349	Cyclin-H isoform 1; Belongs to the cyclin family.	General transcription factor IIH subunit 3.	0.977
CCNH	Gtf2h4	G5AT77	G5C3C7	Cyclin-H isoform 1; Belongs to the cyclin family.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.989
CDK12	CCNH	G5BRW7	G5AT77	Cell division cycle 2-related protein kinase 7.	Cyclin-H isoform 1; Belongs to the cyclin family.	0.781
CDK12	CDK9	G5BRW7	G5BLG4	Cell division cycle 2-related protein kinase 7.	Cell division protein kinase 9; Belongs to the protein kinase superfamily.	0.665
CDK12	Ccnt1	G5BRW7	G5AU45	Cell division cycle 2-related protein kinase 7.	Cyclin-T1; Belongs to the cyclin family.	0.799
CDK12	Cdk7	G5BRW7	G5B4C7	Cell division cycle 2-related protein kinase 7.	Cell division protein kinase 7.	0.614
CDK12	GW7_03149	G5BRW7	G5AWT8	Cell division cycle 2-related protein kinase 7.	General transcription factor IIH subunit 3.	0.550
CDK12	GW7_04998	G5BRW7	G5C3W4	Cell division cycle 2-related protein kinase 7.	Cyclin-T1.	0.799
CDK12	GW7_16199	G5BRW7	G5B4A6	Cell division cycle 2-related protein kinase 7.	Cyclin-K; Belongs to the cyclin family.	0.967
CDK12	Gtf2h3	G5BRW7	G5C349	Cell division cycle 2-related protein kinase 7.	General transcription factor IIH subunit 3.	0.550
CDK9	CCNH	G5BLG4	G5AT77	Cell division protein kinase 9; Belongs to the protein kinase superfamily.	Cyclin-H isoform 1; Belongs to the cyclin family.	0.728