20 items (Heterocephalus glaber) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	Eci2	Peroxisomal 3,2-trans-enoyl-CoA isomerase. (358 aa)
	Pex5	Peroxisomal targeting signal 1 receptor. (629 aa)
	GW7_12217	Fatty acid-binding protein, liver. (111 aa)
	FABP1	Fatty acid-binding protein, liver. (127 aa)
	GW7_10597	60 kDa heat shock protein, mitochondrial. (221 aa)
	Fabp1	Fatty acid-binding protein, liver. (127 aa)
	PRDX1	Peroxiredoxin-1. (199 aa)
	Paox	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase. (449 aa)
	GW7_17339	60 kDa heat shock protein, mitochondrial. (409 aa)
	Prdx5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (162 aa)
	ACOT8	Acyl-coenzyme A thioesterase 8. (320 aa)
	Hao1	Hydroxyacid oxidase 1. (370 aa)
	Hao2	Hydroxyacid oxidase 2. (778 aa)
	Mlycd	Malonyl-CoA decarboxylase, mitochondrial. (360 aa)
	OSGIN1	Oxidative stress-induced growth inhibitor 1. (473 aa)
	LONP2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (811 aa)
	GW7_12216	Fatty acid-binding protein, liver. (127 aa)
	Ide	Insulin-degrading enzyme; Belongs to the peptidase M16 family. (1020 aa)
	Pex7	Peroxisomal targeting signal 2 receptor. (314 aa)
	Agxt	Serine--pyruvate aminotransferase. (392 aa)

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT8	Eci2	G5B7P2	G5C8W8	Acyl-coenzyme A thioesterase 8.	Peroxisomal 3,2-trans-enoyl-CoA isomerase.	0.638
ACOT8	Pex5	G5B7P2	G5CAS9	Acyl-coenzyme A thioesterase 8.	Peroxisomal targeting signal 1 receptor.	0.713
Agxt	Hao1	G5C3Q9	G5BAS2	Serine--pyruvate aminotransferase.	Hydroxyacid oxidase 1.	0.973
Agxt	Hao2	G5C3Q9	G5BDM6	Serine--pyruvate aminotransferase.	Hydroxyacid oxidase 2.	0.973
Agxt	Pex5	G5C3Q9	G5CAS9	Serine--pyruvate aminotransferase.	Peroxisomal targeting signal 1 receptor.	0.950
Eci2	ACOT8	G5C8W8	G5B7P2	Peroxisomal 3,2-trans-enoyl-CoA isomerase.	Acyl-coenzyme A thioesterase 8.	0.638
Eci2	Pex5	G5C8W8	G5CAS9	Peroxisomal 3,2-trans-enoyl-CoA isomerase.	Peroxisomal targeting signal 1 receptor.	0.953
Fabp1	GW7_12216	G5AQW5	G5AQ01	Fatty acid-binding protein, liver.	Fatty acid-binding protein, liver.	0.901
GW7_10597	LONP2	G5AQS0	G5BT79	60 kDa heat shock protein, mitochondrial.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.568
GW7_12216	Fabp1	G5AQ01	G5AQW5	Fatty acid-binding protein, liver.	Fatty acid-binding protein, liver.	0.901
GW7_17339	LONP2	G5B2V7	G5BT79	60 kDa heat shock protein, mitochondrial.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.568
Hao1	Agxt	G5BAS2	G5C3Q9	Hydroxyacid oxidase 1.	Serine--pyruvate aminotransferase.	0.973
Hao1	Hao2	G5BAS2	G5BDM6	Hydroxyacid oxidase 1.	Hydroxyacid oxidase 2.	0.922
Hao1	Pex5	G5BAS2	G5CAS9	Hydroxyacid oxidase 1.	Peroxisomal targeting signal 1 receptor.	0.576
Hao2	Agxt	G5BDM6	G5C3Q9	Hydroxyacid oxidase 2.	Serine--pyruvate aminotransferase.	0.973
Hao2	Hao1	G5BDM6	G5BAS2	Hydroxyacid oxidase 2.	Hydroxyacid oxidase 1.	0.922
Hao2	Pex5	G5BDM6	G5CAS9	Hydroxyacid oxidase 2.	Peroxisomal targeting signal 1 receptor.	0.555
Ide	LONP2	G5BV05	G5BT79	Insulin-degrading enzyme; Belongs to the peptidase M16 family.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.403
Ide	Pex5	G5BV05	G5CAS9	Insulin-degrading enzyme; Belongs to the peptidase M16 family.	Peroxisomal targeting signal 1 receptor.	0.557
LONP2	GW7_10597	G5BT79	G5AQS0	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	60 kDa heat shock protein, mitochondrial.	0.568