STRINGSTRING
GW7_05298 GW7_05298 GW7_11875 GW7_11875 IL11 IL11 IL12A IL12A GW7_17226 GW7_17226 Thpo Thpo Clcf1 Clcf1 CSF3 CSF3 GW7_14886 GW7_14886 GW7_16126 GW7_16126 IL10 IL10 Il19 Il19 GW7_07560 GW7_07560 Il15 Il15 Csf2 Csf2 LEP LEP Il22 Il22 Ifng Ifng Gh1 Gh1 Csf1 Csf1 IL23A IL23A IL6 IL6 Kitlg Kitlg GW7_15287 GW7_15287 GW7_05249 GW7_05249 Il4 Il4 Il13 Il13 IL5 IL5 LIF LIF GW7_09531 GW7_09531 Cntf Cntf Ifnb1 Ifnb1 Il21 Il21 IL2 IL2 Prl Prl GW7_04543 GW7_04543
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GW7_05298Oncostatin-M. (242 aa)
GW7_11875Cardiotrophin-2. (220 aa)
IL11Interleukin-11 isoform 2. (199 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (194 aa)
GW7_17226Thrombopoietin. (276 aa)
ThpoThrombopoietin. (297 aa)
Clcf1Cardiotrophin-like cytokine factor 1. (290 aa)
CSF3Granulocyte colony-stimulating factor isoform a. (205 aa)
GW7_14886Interleukin-27 subunit alpha. (280 aa)
GW7_16126Interferon kappa. (206 aa)
IL10Interleukin-10. (178 aa)
Il19Interleukin-19. (171 aa)
GW7_07560Interleukin-24. (198 aa)
Il15Interleukin; Belongs to the IL-15/IL-21 family. (114 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (144 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Il22Interleukin-22. (178 aa)
IfngInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
Gh1Somatotropin. (216 aa)
Csf1Macrophage colony-stimulating factor 1. (507 aa)
IL23AInterleukin-23 subunit alpha. (189 aa)
IL6Interleukin-6. (218 aa)
KitlgKit ligand. (267 aa)
GW7_15287SL cytokine. (174 aa)
GW7_05249Erythropoietin. (367 aa)
Il4Interleukin-4. (140 aa)
Il13Interleukin-13. (132 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (133 aa)
LIFLeukemia inhibitory factor isoform 2. (200 aa)
GW7_09531Interferon alpha-4. (187 aa)
CntfCiliary neurotrophic factor. (198 aa)
Ifnb1Interferon beta. (187 aa)
Il21Interleukin-21. (166 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
PrlProlactin. (219 aa)
GW7_04543Prolactin. (217 aa)
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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