(20 nodes) SMAD-like domain superfamily network (Heterocephalus glaber)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Smad4	Mothers against decapentaplegic homolog. (552 aa)
	Smad5	Mothers against decapentaplegic homolog. (465 aa)
	GW7_10524	Mothers against decapentaplegic homolog. (415 aa)
	GW7_06989	Mothers against decapentaplegic-like protein 1. (378 aa)
	Irf7	Interferon regulatory factor 7. (440 aa)
	Smad3	Mothers against decapentaplegic homolog. (409 aa)
	Smad6	Mothers against decapentaplegic-like protein 6. (183 aa)
	Irf8	Interferon regulatory factor 8. (426 aa)
	Irf5	Interferon regulatory factor 5. (497 aa)
	Irf6	Interferon regulatory factor 6. (462 aa)
	Irf3	Interferon regulatory factor 3. (415 aa)
	Irf4	Interferon regulatory factor 4. (451 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	GW7_16538	Mothers against decapentaplegic homolog. (392 aa)
	GW7_16534	Mothers against decapentaplegic homolog. (373 aa)
	GW7_19860	Mothers against decapentaplegic homolog. (394 aa)
	GW7_19582	Mothers against decapentaplegic homolog. (467 aa)
	Irf9	Interferon regulatory factor 9. (387 aa)
	GW7_07707	Forkhead box protein S1. (533 aa)
	GW7_15298	Interferon regulatory factor 3. (373 aa)

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GW7_06989	GW7_16534	G5C2B0	G5B879	Mothers against decapentaplegic-like protein 1.	Mothers against decapentaplegic homolog.	0.427
GW7_06989	GW7_16538	G5C2B0	G5B883	Mothers against decapentaplegic-like protein 1.	Mothers against decapentaplegic homolog.	0.502
GW7_06989	GW7_19582	G5C2B0	G5B3N2	Mothers against decapentaplegic-like protein 1.	Mothers against decapentaplegic homolog.	0.574
GW7_06989	Smad3	G5C2B0	G5C5G2	Mothers against decapentaplegic-like protein 1.	Mothers against decapentaplegic homolog.	0.449
GW7_06989	Smad4	G5C2B0	G5BVT2	Mothers against decapentaplegic-like protein 1.	Mothers against decapentaplegic homolog.	0.865
GW7_06989	Smad5	G5C2B0	G5BX13	Mothers against decapentaplegic-like protein 1.	Mothers against decapentaplegic homolog.	0.555
GW7_06989	Smad6	G5C2B0	G5C5G3	Mothers against decapentaplegic-like protein 1.	Mothers against decapentaplegic-like protein 6.	0.657
GW7_10524	GW7_16534	G5C0F3	G5B879	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.427
GW7_10524	GW7_16538	G5C0F3	G5B883	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.482
GW7_10524	GW7_19582	G5C0F3	G5B3N2	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.570
GW7_10524	Smad3	G5C0F3	G5C5G2	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.437
GW7_10524	Smad4	G5C0F3	G5BVT2	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.865
GW7_10524	Smad5	G5C0F3	G5BX13	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.552
GW7_10524	Smad6	G5C0F3	G5C5G3	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic-like protein 6.	0.657
GW7_15298	Irf7	G5B8Q1	G5C485	Interferon regulatory factor 3.	Interferon regulatory factor 7.	0.814
GW7_15298	Irf9	G5B8Q1	G5B292	Interferon regulatory factor 3.	Interferon regulatory factor 9.	0.466
GW7_16534	GW7_06989	G5B879	G5C2B0	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic-like protein 1.	0.427
GW7_16534	GW7_10524	G5B879	G5C0F3	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.427
GW7_16534	GW7_16538	G5B879	G5B883	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.616
GW7_16534	GW7_19582	G5B879	G5B3N2	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.693