35 items (Heterocephalus glaber) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALDH2	Aldehyde dehydrogenase, mitochondrial isoform 1; Belongs to the aldehyde dehydrogenase family. (521 aa)
	ALDH9A1	4-trimethylaminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (518 aa)
	Acadm	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial. (273 aa)
	GW7_07365	3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	ACADS	Short-chain specific acyl-CoA dehydrogenase, mitochondrial. (413 aa)
	Acaa2	3-ketoacyl-CoA thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	DBT	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
	Bckdha	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (480 aa)
	Pcca	Propionyl-CoA carboxylase alpha chain, mitochondrial. (728 aa)
	Acad8	Isobutyryl-CoA dehydrogenase, mitochondrial. (377 aa)
	Mcee	Methylmalonyl-CoA epimerase, mitochondrial. (166 aa)
	Aldh16a1	Aldehyde dehydrogenase family 16 member A1. (793 aa)
	Il4i1	L-amino-acid oxidase. (336 aa)
	Bcat2	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (398 aa)
	HSD17B10	3-hydroxyacyl-CoA dehydrogenase type-2 isoform 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
	Acat2	Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
	Hibadh	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (301 aa)
	Bcat1	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (366 aa)
	BCKDHB	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial. (392 aa)
	MUT	Methylmalonyl-CoA mutase, mitochondrial. (750 aa)
	Hibch	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (373 aa)
	ALDH7A1	Alpha-aminoadipic semialdehyde dehydrogenase isoform 3; Belongs to the aldehyde dehydrogenase family. (539 aa)
	HMGCL	Hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 2. (325 aa)
	Agxt2	Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa)
	Abat	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (477 aa)
	Ehhadh	Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (714 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	Acat1	Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
	Mccc2	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial. (566 aa)
	Aldh6a1	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. (520 aa)
	DLD	Dihydrolipoyl dehydrogenase. (509 aa)
	Auh	Methylglutaconyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (252 aa)
	Oxct1	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (542 aa)
	HADHA	Trifunctional enzyme subunit alpha, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADS	ALDH2	G5AWX3	G5AKU7	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Aldehyde dehydrogenase, mitochondrial isoform 1; Belongs to the aldehyde dehydrogenase family.	0.889
ACADS	ALDH7A1	G5AWX3	G5BHU2	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Alpha-aminoadipic semialdehyde dehydrogenase isoform 3; Belongs to the aldehyde dehydrogenase family.	0.892
ACADS	ALDH9A1	G5AWX3	G5AQ32	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	4-trimethylaminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.882
ACADS	Abat	G5AWX3	G5BSD0	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.817
ACADS	Acaa2	G5AWX3	G5AX32	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	3-ketoacyl-CoA thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.	0.965
ACADS	Acad8	G5AWX3	G5B2N6	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Isobutyryl-CoA dehydrogenase, mitochondrial.	0.931
ACADS	Acadm	G5AWX3	G5AQ85	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial.	0.931
ACADS	Acat1	G5AWX3	G5BXR0	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.	0.954
ACADS	Acat2	G5AWX3	G5BC68	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family.	0.954
ACADS	Agxt2	G5AWX3	G5BQ90	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.819
ACADS	Aldh16a1	G5AWX3	G5B8N9	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Aldehyde dehydrogenase family 16 member A1.	0.879
ACADS	Aldh6a1	G5AWX3	G5C1N1	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial.	0.950
ACADS	Auh	G5AWX3	G5C2H3	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Methylglutaconyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.	0.619
ACADS	BCKDHB	G5AWX3	G5BGH0	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.	0.606
ACADS	Bckdha	G5AWX3	G5AZS5	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.645
ACADS	DBT	G5AWX3	G5AYQ0	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.951
ACADS	DLD	G5AWX3	G5C2C6	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Dihydrolipoyl dehydrogenase.	0.446
ACADS	Ehhadh	G5AWX3	G5BTB0	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.	0.972
ACADS	GW7_07365	G5AWX3	G5ATL7	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.	0.977
ACADS	HADHA	G5AWX3	G5CBK7	Short-chain specific acyl-CoA dehydrogenase, mitochondrial.	Trifunctional enzyme subunit alpha, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.	0.978