(47 nodes) Regulation of TOR signaling, and Energy dependent regulation of mTOR by LKB1-AMPK network (Trichoplax adhaerens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RI56_TRIAD	Uncharacterized protein. (334 aa)
	B3RIA5_TRIAD	Uncharacterized protein. (150 aa)
	B3RIE8_TRIAD	Uncharacterized protein. (307 aa)
	B3RIM0_TRIAD	Uncharacterized protein. (439 aa)
	B3RJ67_TRIAD	Uncharacterized protein. (281 aa)
	B3RKF7_TRIAD	AMPKBI domain-containing protein. (191 aa)
	B3RKU3_TRIAD	Uncharacterized protein. (835 aa)
	B3RKY6_TRIAD	Uncharacterized protein. (293 aa)
	B3RL09_TRIAD	Uncharacterized protein. (373 aa)
	B3RLA2_TRIAD	Uncharacterized protein. (369 aa)
	B3RN00_TRIAD	Robl_LC7 domain-containing protein. (139 aa)
	B3RN36_TRIAD	WD_REPEATS_REGION domain-containing protein. (315 aa)
	B3RPA1_TRIAD	Uncharacterized protein. (1093 aa)
	B3RPC5_TRIAD	UDENN FLCN/SMCR8-type domain-containing protein. (406 aa)
	B3RPH6_TRIAD	Telomere_reg-2 domain-containing protein. (713 aa)
	B3RPI4_TRIAD	Protein kinase domain-containing protein. (312 aa)
	B3RPK3_TRIAD	Uncharacterized protein. (185 aa)
	B3RPQ9_TRIAD	WD_REPEATS_REGION domain-containing protein. (1262 aa)
	B3RQG5_TRIAD	WD_REPEATS_REGION domain-containing protein. (554 aa)
	B3RQZ2_TRIAD	Zinc_ribbon_16 domain-containing protein. (352 aa)
	B3RQZ3_TRIAD	Predicted protein. (377 aa)
	B3RT71_TRIAD	Uncharacterized protein. (291 aa)
	B3RUW6_TRIAD	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling. Acts as a sensor of S-adenosyl-L- methionine to signal methionine sufficiency to mTORC1. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase. (358 aa)
	B3RVL1_TRIAD	Uncharacterized protein. (797 aa)
	B3RW08_TRIAD	UDENN FNIP1/2-type domain-containing protein. (761 aa)
	B3RYA9_TRIAD	Uncharacterized protein. (411 aa)
	B3RYH8_TRIAD	Uncharacterized protein. (167 aa)
	B3RZI2_TRIAD	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2534 aa)
	B3S0W1_TRIAD	Uncharacterized protein. (375 aa)
	B3S1R2_TRIAD	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
	B3S1V9_TRIAD	DEP domain-containing protein. (1221 aa)
	B3S2A4_TRIAD	Protein kinase domain-containing protein. (301 aa)
	B3S2A8_TRIAD	Uncharacterized protein. (403 aa)
	B3S2G4_TRIAD	Uncharacterized protein. (1496 aa)
	B3S3S7_TRIAD	DM domain-containing protein. (57 aa)
	B3S3Z7_TRIAD	ANK_REP_REGION domain-containing protein. (515 aa)
	B3S4J8_TRIAD	Uncharacterized protein; Belongs to the protein kinase superfamily. (346 aa)
	B3S4V2_TRIAD	Uncharacterized protein. (169 aa)
	B3S4Y5_TRIAD	Uncharacterized protein. (426 aa)
	B3S4Y6_TRIAD	Aa_trans domain-containing protein. (422 aa)
	B3S4Z1_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (258 aa)
	B3S562_TRIAD	Uncharacterized protein. (443 aa)
	B3S563_TRIAD	Aa_trans domain-containing protein. (422 aa)
	B3S9A3_TRIAD	Rap-GAP domain-containing protein. (1711 aa)
	B3SA38_TRIAD	Uncharacterized protein. (349 aa)
	B3SCW3_TRIAD	Uncharacterized protein. (456 aa)
	B3SEI9_TRIAD	Uncharacterized protein. (292 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RI56_TRIAD	B3RKF7_TRIAD	B3RI56	B3RKF7	Uncharacterized protein.	AMPKBI domain-containing protein.	0.459
B3RI56_TRIAD	B3RPI4_TRIAD	B3RI56	B3RPI4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.974
B3RI56_TRIAD	B3RT71_TRIAD	B3RI56	B3RT71	Uncharacterized protein.	Uncharacterized protein.	0.500
B3RI56_TRIAD	B3S1R2_TRIAD	B3RI56	B3S1R2	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.959
B3RI56_TRIAD	B3S2A4_TRIAD	B3RI56	B3S2A4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.438
B3RI56_TRIAD	B3S4Z1_TRIAD	B3RI56	B3S4Z1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.992
B3RIA5_TRIAD	B3RIE8_TRIAD	B3RIA5	B3RIE8	Uncharacterized protein.	Uncharacterized protein.	0.985
B3RIA5_TRIAD	B3RL09_TRIAD	B3RIA5	B3RL09	Uncharacterized protein.	Uncharacterized protein.	0.775
B3RIA5_TRIAD	B3RN00_TRIAD	B3RIA5	B3RN00	Uncharacterized protein.	Robl_LC7 domain-containing protein.	0.934
B3RIA5_TRIAD	B3RN36_TRIAD	B3RIA5	B3RN36	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.681
B3RIA5_TRIAD	B3RPC5_TRIAD	B3RIA5	B3RPC5	Uncharacterized protein.	UDENN FLCN/SMCR8-type domain-containing protein.	0.645
B3RIA5_TRIAD	B3RPQ9_TRIAD	B3RIA5	B3RPQ9	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.744
B3RIA5_TRIAD	B3RQG5_TRIAD	B3RIA5	B3RQG5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
B3RIA5_TRIAD	B3RQZ2_TRIAD	B3RIA5	B3RQZ2	Uncharacterized protein.	Zinc_ribbon_16 domain-containing protein.	0.932
B3RIA5_TRIAD	B3RQZ3_TRIAD	B3RIA5	B3RQZ3	Uncharacterized protein.	Predicted protein.	0.932
B3RIA5_TRIAD	B3RUW6_TRIAD	B3RIA5	B3RUW6	Uncharacterized protein.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling. Acts as a sensor of S-adenosyl-L- methionine to signal methionine sufficiency to mTORC1. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.	0.438
B3RIA5_TRIAD	B3RVL1_TRIAD	B3RIA5	B3RVL1	Uncharacterized protein.	Uncharacterized protein.	0.999
B3RIA5_TRIAD	B3RW08_TRIAD	B3RIA5	B3RW08	Uncharacterized protein.	UDENN FNIP1/2-type domain-containing protein.	0.547
B3RIA5_TRIAD	B3RYA9_TRIAD	B3RIA5	B3RYA9	Uncharacterized protein.	Uncharacterized protein.	0.775
B3RIA5_TRIAD	B3RYH8_TRIAD	B3RIA5	B3RYH8	Uncharacterized protein.	Uncharacterized protein.	0.754