(81 nodes) Mixed, incl. Voltage-gated channel activity, and Superoxide anion generation network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RI47_TRIAD	Uncharacterized protein. (1256 aa)
	B3RI48_TRIAD	Ion_trans domain-containing protein. (170 aa)
	B3RI99_TRIAD	PX domain-containing protein. (472 aa)
	B3RIC6_TRIAD	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1481 aa)
	B3RIL5_TRIAD	Predicted protein. (156 aa)
	B3RIS7_TRIAD	PX domain-containing protein. (311 aa)
	B3RIV5_TRIAD	Uncharacterized protein. (619 aa)
	B3RIY7_TRIAD	Uncharacterized protein. (403 aa)
	B3RJ39_TRIAD	RTTN_N domain-containing protein. (2092 aa)
	B3RJE9_TRIAD	Predicted protein. (859 aa)
	B3RJI4_TRIAD	Uncharacterized protein. (102 aa)
	B3RK72_TRIAD	Uncharacterized protein. (134 aa)
	B3RKW1_TRIAD	SH3 domain-containing protein. (1564 aa)
	B3RL08_TRIAD	Uncharacterized protein. (111 aa)
	B3RMH8_TRIAD	Uncharacterized protein. (167 aa)
	B3RMU7_TRIAD	Uncharacterized protein. (2693 aa)
	B3RN16_TRIAD	Ca_chan_IQ domain-containing protein. (1556 aa)
	B3RNZ9_TRIAD	TPR_REGION domain-containing protein. (492 aa)
	B3RP11_TRIAD	VWFA domain-containing protein. (356 aa)
	B3RP12_TRIAD	Predicted protein. (1975 aa)
	B3RP86_TRIAD	Uncharacterized protein. (238 aa)
	B3RPA7_TRIAD	FHA domain-containing protein. (188 aa)
	B3RPA8_TRIAD	Predicted protein. (978 aa)
	B3RPW0_TRIAD	Uncharacterized protein. (1510 aa)
	B3RQ29_TRIAD	Uncharacterized protein. (1036 aa)
	B3RR78_TRIAD	HP domain-containing protein. (1548 aa)
	B3RRH4_TRIAD	GuKc domain-containing protein. (377 aa)
	B3RRJ5_TRIAD	Anoctamin. (900 aa)
	B3RSQ8_TRIAD	Uncharacterized protein. (592 aa)
	B3RSR3_TRIAD	Uncharacterized protein. (1816 aa)
	B3RSR4_TRIAD	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (365 aa)
	B3RSR5_TRIAD	Ion_trans domain-containing protein. (109 aa)
	B3RSR6_TRIAD	Uncharacterized protein. (1046 aa)
	B3RSR8_TRIAD	Ion_trans domain-containing protein. (184 aa)
	B3RSR9_TRIAD	Ion_trans domain-containing protein. (138 aa)
	B3RSS0_TRIAD	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (244 aa)
	B3RSS1_TRIAD	Uncharacterized protein. (121 aa)
	B3RSS2_TRIAD	Ion_trans domain-containing protein. (190 aa)
	B3RSS3_TRIAD	Uncharacterized protein. (308 aa)
	B3RSS4_TRIAD	Uncharacterized protein. (1557 aa)
	B3RU32_TRIAD	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (300 aa)
	B3RUM1_TRIAD	VWFA domain-containing protein. (1173 aa)
	B3RV90_TRIAD	Uncharacterized protein. (141 aa)
	B3RV96_TRIAD	Uncharacterized protein. (893 aa)
	B3RWW7_TRIAD	VWFA domain-containing protein. (732 aa)
	B3RWW8_TRIAD	Predicted protein. (228 aa)
	B3RWX4_TRIAD	VWFA domain-containing protein. (1007 aa)
	B3RX00_TRIAD	Uncharacterized protein. (575 aa)
	B3RXP2_TRIAD	Uncharacterized protein. (152 aa)
	B3RY92_TRIAD	Uncharacterized protein. (288 aa)
	B3RYD9_TRIAD	FAD-binding FR-type domain-containing protein. (540 aa)
	B3RZ40_TRIAD	Uncharacterized protein. (2161 aa)
	B3RZS9_TRIAD	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (170 aa)
	B3S047_TRIAD	Anoctamin. (727 aa)
	B3S049_TRIAD	Anoctamin. (412 aa)
	B3S1U7_TRIAD	Uncharacterized protein. (134 aa)
	B3S2M4_TRIAD	Uncharacterized protein. (581 aa)
	B3S2N1_TRIAD	Rtf2 domain-containing protein. (280 aa)
	B3S2W7_TRIAD	ENTH domain-containing protein. (175 aa)
	B3S304_TRIAD	Uncharacterized protein. (551 aa)
	B3S305_TRIAD	Uncharacterized protein. (457 aa)
	B3S401_TRIAD	Uncharacterized protein. (455 aa)
	B3S4X0_TRIAD	Uncharacterized protein. (728 aa)
	B3S5N6_TRIAD	UNC80 domain-containing protein. (2276 aa)
	B3S6M4_TRIAD	Metallophos domain-containing protein. (587 aa)
	B3S6X8_TRIAD	Cyclic nucleotide-binding domain-containing protein. (638 aa)
	B3S6Z3_TRIAD	Uncharacterized protein. (269 aa)
	B3S6Z4_TRIAD	Uncharacterized protein. (297 aa)
	B3S6Z7_TRIAD	Cyclic nucleotide-binding domain-containing protein. (745 aa)
	B3S7R2_TRIAD	Uncharacterized protein. (595 aa)
	B3S879_TRIAD	THAP-type domain-containing protein. (147 aa)
	B3S880_TRIAD	DDE Tnp4 domain-containing protein. (157 aa)
	B3S8E5_TRIAD	Uncharacterized protein. (1244 aa)
	B3S9P9_TRIAD	Anoctamin. (753 aa)
	B3SAV3_TRIAD	Uncharacterized protein. (593 aa)
	B3SAV5_TRIAD	Uncharacterized protein. (739 aa)
	B3SBR2_TRIAD	FSA_C domain-containing protein. (4390 aa)
	B3SBY7_TRIAD	Tubby-like protein; Belongs to the TUB family. (247 aa)
	B3SBZ1_TRIAD	Ion_trans domain-containing protein. (460 aa)
	B3SDS7_TRIAD	Uncharacterized protein. (305 aa)
	B3SE19_TRIAD	Uncharacterized protein. (208 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RI47_TRIAD	B3RI48_TRIAD	B3RI47	B3RI48	Uncharacterized protein.	Ion_trans domain-containing protein.	0.938
B3RI47_TRIAD	B3RRH4_TRIAD	B3RI47	B3RRH4	Uncharacterized protein.	GuKc domain-containing protein.	0.651
B3RI47_TRIAD	B3RUM1_TRIAD	B3RI47	B3RUM1	Uncharacterized protein.	VWFA domain-containing protein.	0.434
B3RI47_TRIAD	B3RWW7_TRIAD	B3RI47	B3RWW7	Uncharacterized protein.	VWFA domain-containing protein.	0.466
B3RI47_TRIAD	B3RWX4_TRIAD	B3RI47	B3RWX4	Uncharacterized protein.	VWFA domain-containing protein.	0.466
B3RI47_TRIAD	B3RZ40_TRIAD	B3RI47	B3RZ40	Uncharacterized protein.	Uncharacterized protein.	0.990
B3RI47_TRIAD	B3S5N6_TRIAD	B3RI47	B3S5N6	Uncharacterized protein.	UNC80 domain-containing protein.	0.928
B3RI48_TRIAD	B3RI47_TRIAD	B3RI48	B3RI47	Ion_trans domain-containing protein.	Uncharacterized protein.	0.938
B3RI48_TRIAD	B3RIC6_TRIAD	B3RI48	B3RIC6	Ion_trans domain-containing protein.	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.554
B3RI48_TRIAD	B3RN16_TRIAD	B3RI48	B3RN16	Ion_trans domain-containing protein.	Ca_chan_IQ domain-containing protein.	0.554
B3RI48_TRIAD	B3RP12_TRIAD	B3RI48	B3RP12	Ion_trans domain-containing protein.	Predicted protein.	0.664
B3RI48_TRIAD	B3RPW0_TRIAD	B3RI48	B3RPW0	Ion_trans domain-containing protein.	Uncharacterized protein.	0.582
B3RI48_TRIAD	B3RRH4_TRIAD	B3RI48	B3RRH4	Ion_trans domain-containing protein.	GuKc domain-containing protein.	0.832
B3RI48_TRIAD	B3RSS4_TRIAD	B3RI48	B3RSS4	Ion_trans domain-containing protein.	Uncharacterized protein.	0.407
B3RI48_TRIAD	B3RUM1_TRIAD	B3RI48	B3RUM1	Ion_trans domain-containing protein.	VWFA domain-containing protein.	0.728
B3RI48_TRIAD	B3RWW7_TRIAD	B3RI48	B3RWW7	Ion_trans domain-containing protein.	VWFA domain-containing protein.	0.744
B3RI48_TRIAD	B3RWX4_TRIAD	B3RI48	B3RWX4	Ion_trans domain-containing protein.	VWFA domain-containing protein.	0.744
B3RI48_TRIAD	B3RZ40_TRIAD	B3RI48	B3RZ40	Ion_trans domain-containing protein.	Uncharacterized protein.	0.990
B3RI48_TRIAD	B3S1U7_TRIAD	B3RI48	B3S1U7	Ion_trans domain-containing protein.	Uncharacterized protein.	0.441
B3RI48_TRIAD	B3S5N6_TRIAD	B3RI48	B3S5N6	Ion_trans domain-containing protein.	UNC80 domain-containing protein.	0.928