(5 nodes) Gamma-secretase complex network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RLD0_TRIAD	Uncharacterized protein. (252 aa)
	B3RU89_TRIAD	Ncstrn_small domain-containing protein. (674 aa)
	B3S0V5_TRIAD	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (325 aa)
	B3SCV2_TRIAD	Uncharacterized protein. (101 aa)
	B3SFP1_TRIAD	Hydrolase_4 domain-containing protein. (228 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RLD0_TRIAD	B3RU89_TRIAD	B3RLD0	B3RU89	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.988
B3RLD0_TRIAD	B3S0V5_TRIAD	B3RLD0	B3S0V5	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.977
B3RLD0_TRIAD	B3SCV2_TRIAD	B3RLD0	B3SCV2	Uncharacterized protein.	Uncharacterized protein.	0.993
B3RLD0_TRIAD	B3SFP1_TRIAD	B3RLD0	B3SFP1	Uncharacterized protein.	Hydrolase_4 domain-containing protein.	0.961
B3RU89_TRIAD	B3RLD0_TRIAD	B3RU89	B3RLD0	Ncstrn_small domain-containing protein.	Uncharacterized protein.	0.988
B3RU89_TRIAD	B3S0V5_TRIAD	B3RU89	B3S0V5	Ncstrn_small domain-containing protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.987
B3RU89_TRIAD	B3SCV2_TRIAD	B3RU89	B3SCV2	Ncstrn_small domain-containing protein.	Uncharacterized protein.	0.998
B3RU89_TRIAD	B3SFP1_TRIAD	B3RU89	B3SFP1	Ncstrn_small domain-containing protein.	Hydrolase_4 domain-containing protein.	0.973
B3S0V5_TRIAD	B3RLD0_TRIAD	B3S0V5	B3RLD0	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.977
B3S0V5_TRIAD	B3RU89_TRIAD	B3S0V5	B3RU89	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Ncstrn_small domain-containing protein.	0.987
B3S0V5_TRIAD	B3SCV2_TRIAD	B3S0V5	B3SCV2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.962
B3SCV2_TRIAD	B3RLD0_TRIAD	B3SCV2	B3RLD0	Uncharacterized protein.	Uncharacterized protein.	0.993
B3SCV2_TRIAD	B3RU89_TRIAD	B3SCV2	B3RU89	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.998
B3SCV2_TRIAD	B3S0V5_TRIAD	B3SCV2	B3S0V5	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.962
B3SCV2_TRIAD	B3SFP1_TRIAD	B3SCV2	B3SFP1	Uncharacterized protein.	Hydrolase_4 domain-containing protein.	0.922
B3SFP1_TRIAD	B3RLD0_TRIAD	B3SFP1	B3RLD0	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.961
B3SFP1_TRIAD	B3RU89_TRIAD	B3SFP1	B3RU89	Hydrolase_4 domain-containing protein.	Ncstrn_small domain-containing protein.	0.973
B3SFP1_TRIAD	B3SCV2_TRIAD	B3SFP1	B3SCV2	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.922