(24 nodes) DNA polymerase complex, and DNA replication factor C complex network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RI52_TRIAD	DNA polymerase. (1203 aa)
	B3RII6_TRIAD	Uncharacterized protein. (457 aa)
	B3RK60_TRIAD	DNA polymerase. (1050 aa)
	B3RM11_TRIAD	Uncharacterized protein. (394 aa)
	B3RMY7_TRIAD	Uncharacterized protein. (448 aa)
	B3RPQ8_TRIAD	Predicted protein. (1416 aa)
	B3RUC9_TRIAD	AAA domain-containing protein. (373 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (377 aa)
	B3RWK4_TRIAD	AAA domain-containing protein. (355 aa)
	B3RXD9_TRIAD	CBFD_NFYB_HMF domain-containing protein. (104 aa)
	B3RYU8_TRIAD	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (595 aa)
	B3RZA4_TRIAD	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (400 aa)
	B3S218_TRIAD	BRCT domain-containing protein. (716 aa)
	B3S251_TRIAD	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (536 aa)
	B3S2B3_TRIAD	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
	B3S4I8_TRIAD	AAA domain-containing protein. (315 aa)
	B3S4Q9_TRIAD	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	B3S6C7_TRIAD	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2239 aa)
	B3SDP9_TRIAD	DNA ligase. (707 aa)
	B3SDS0_TRIAD	DNA_pol_B_exo1 domain-containing protein. (240 aa)
	B3SDS1_TRIAD	DNA polymerase. (740 aa)
	B3SDS2_TRIAD	DNA_pol_B_exo1 domain-containing protein. (230 aa)
	B3SDS4_TRIAD	DNA polymerase. (765 aa)
	B3SF45_TRIAD	DNA_pol_B domain-containing protein. (77 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RI52_TRIAD	B3RK60_TRIAD	B3RI52	B3RK60	DNA polymerase.	DNA polymerase.	0.970
B3RI52_TRIAD	B3RM11_TRIAD	B3RI52	B3RM11	DNA polymerase.	Uncharacterized protein.	0.850
B3RI52_TRIAD	B3RMY7_TRIAD	B3RI52	B3RMY7	DNA polymerase.	Uncharacterized protein.	0.983
B3RI52_TRIAD	B3RPQ8_TRIAD	B3RI52	B3RPQ8	DNA polymerase.	Predicted protein.	0.877
B3RI52_TRIAD	B3RUC9_TRIAD	B3RI52	B3RUC9	DNA polymerase.	AAA domain-containing protein.	0.841
B3RI52_TRIAD	B3RWK4_TRIAD	B3RI52	B3RWK4	DNA polymerase.	AAA domain-containing protein.	0.884
B3RI52_TRIAD	B3RXD9_TRIAD	B3RI52	B3RXD9	DNA polymerase.	CBFD_NFYB_HMF domain-containing protein.	0.950
B3RI52_TRIAD	B3RYU8_TRIAD	B3RI52	B3RYU8	DNA polymerase.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.999
B3RI52_TRIAD	B3RZA4_TRIAD	B3RI52	B3RZA4	DNA polymerase.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.999
B3RI52_TRIAD	B3S218_TRIAD	B3RI52	B3S218	DNA polymerase.	BRCT domain-containing protein.	0.876
B3RI52_TRIAD	B3S251_TRIAD	B3RI52	B3S251	DNA polymerase.	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	0.999
B3RI52_TRIAD	B3S2B3_TRIAD	B3RI52	B3S2B3	DNA polymerase.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.990
B3RI52_TRIAD	B3S4I8_TRIAD	B3RI52	B3S4I8	DNA polymerase.	AAA domain-containing protein.	0.911
B3RI52_TRIAD	B3S4Q9_TRIAD	B3RI52	B3S4Q9	DNA polymerase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.953
B3RI52_TRIAD	B3S6C7_TRIAD	B3RI52	B3S6C7	DNA polymerase.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.997
B3RI52_TRIAD	B3SDP9_TRIAD	B3RI52	B3SDP9	DNA polymerase.	DNA ligase.	0.836
B3RI52_TRIAD	B3SDS0_TRIAD	B3RI52	B3SDS0	DNA polymerase.	DNA_pol_B_exo1 domain-containing protein.	0.615
B3RI52_TRIAD	B3SDS1_TRIAD	B3RI52	B3SDS1	DNA polymerase.	DNA polymerase.	0.615
B3RI52_TRIAD	B3SDS2_TRIAD	B3RI52	B3SDS2	DNA polymerase.	DNA_pol_B_exo1 domain-containing protein.	0.615
B3RI52_TRIAD	B3SDS4_TRIAD	B3RI52	B3SDS4	DNA polymerase.	DNA polymerase.	0.615