(50 nodes) Proteasome complex, and Proteasome assembly network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RI98_TRIAD	PCI domain-containing protein. (386 aa)
	B3RIP1_TRIAD	Proteasome subunit alpha type. (230 aa)
	B3RKW2_TRIAD	Uncharacterized protein. (1540 aa)
	B3RL38_TRIAD	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (852 aa)
	B3RLD8_TRIAD	AAA domain-containing protein; Belongs to the AAA ATPase family. (404 aa)
	B3RLH5_TRIAD	AAA domain-containing protein; Belongs to the AAA ATPase family. (387 aa)
	B3RMD4_TRIAD	PCI domain-containing protein. (481 aa)
	B3RML5_TRIAD	Ubiquitin-like domain-containing protein. (272 aa)
	B3RNB0_TRIAD	PCI domain-containing protein. (450 aa)
	B3RNH6_TRIAD	Proteasome subunit beta. (235 aa)
	B3RNU6_TRIAD	Proteasome subunit beta. (229 aa)
	B3RNW4_TRIAD	Uncharacterized protein. (522 aa)
	B3RQH7_TRIAD	Uncharacterized protein. (191 aa)
	B3RQI2_TRIAD	PA28_beta domain-containing protein. (146 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (557 aa)
	B3RRY1_TRIAD	MPN domain-containing protein. (509 aa)
	B3RTI1_TRIAD	Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
	B3RTW1_TRIAD	Uncharacterized protein. (189 aa)
	B3RV69_TRIAD	Uncharacterized protein. (211 aa)
	B3RVM5_TRIAD	Proteasome subunit beta. (276 aa)
	B3RVP1_TRIAD	MPN domain-containing protein. (311 aa)
	B3RW83_TRIAD	AAA domain-containing protein; Belongs to the AAA ATPase family. (392 aa)
	B3RWF1_TRIAD	Uncharacterized protein. (248 aa)
	B3RWL9_TRIAD	ANK_REP_REGION domain-containing protein. (126 aa)
	B3RX11_TRIAD	Uncharacterized protein. (952 aa)
	B3RXM6_TRIAD	Uncharacterized protein. (130 aa)
	B3RZQ4_TRIAD	Proteasome subunit beta. (229 aa)
	B3S088_TRIAD	AAA domain-containing protein; Belongs to the AAA ATPase family. (434 aa)
	B3S0R2_TRIAD	Proteasome subunit alpha type. (249 aa)
	B3S1G1_TRIAD	Ubiquitin carboxyl-terminal hydrolase. (446 aa)
	B3S1R7_TRIAD	Uncharacterized protein. (1686 aa)
	B3S203_TRIAD	PI31_Prot_N domain-containing protein. (296 aa)
	B3S239_TRIAD	Proteasome subunit beta. (199 aa)
	B3S476_TRIAD	RPN13_C domain-containing protein. (419 aa)
	B3S5N5_TRIAD	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (973 aa)
	B3S6F5_TRIAD	PCI domain-containing protein. (421 aa)
	B3S6N2_TRIAD	Proteasome subunit alpha type. (228 aa)
	B3S7Z4_TRIAD	Proteasome subunit alpha type. (260 aa)
	B3S8J6_TRIAD	Proteasome subunit alpha type. (232 aa)
	B3S8Y1_TRIAD	VWFA domain-containing protein. (364 aa)
	B3S907_TRIAD	WD_REPEATS_REGION domain-containing protein. (399 aa)
	B3SA12_TRIAD	Non-ATPase proteasome 26S subunit. (309 aa)
	B3SA37_TRIAD	Ubiquitin carboxyl-terminal hydrolase. (358 aa)
	B3SAI5_TRIAD	Proteasome subunit alpha type. (252 aa)
	B3SAJ1_TRIAD	26S proteasome regulatory chain 4; Belongs to the AAA ATPase family. (413 aa)
	B3SAL4_TRIAD	PCI domain-containing protein. (271 aa)
	B3SB44_TRIAD	Uncharacterized protein. (322 aa)
	B3SC01_TRIAD	PCI domain-containing protein. (382 aa)
	B3SC02_TRIAD	Uncharacterized protein. (1160 aa)
	B3SC20_TRIAD	Proteasome subunit alpha type. (235 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RI98_TRIAD	B3RIP1_TRIAD	B3RI98	B3RIP1	PCI domain-containing protein.	Proteasome subunit alpha type.	0.999
B3RI98_TRIAD	B3RKW2_TRIAD	B3RI98	B3RKW2	PCI domain-containing protein.	Uncharacterized protein.	0.710
B3RI98_TRIAD	B3RL38_TRIAD	B3RI98	B3RL38	PCI domain-containing protein.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
B3RI98_TRIAD	B3RLD8_TRIAD	B3RI98	B3RLD8	PCI domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
B3RI98_TRIAD	B3RLH5_TRIAD	B3RI98	B3RLH5	PCI domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
B3RI98_TRIAD	B3RMD4_TRIAD	B3RI98	B3RMD4	PCI domain-containing protein.	PCI domain-containing protein.	0.999
B3RI98_TRIAD	B3RML5_TRIAD	B3RI98	B3RML5	PCI domain-containing protein.	Ubiquitin-like domain-containing protein.	0.887
B3RI98_TRIAD	B3RNB0_TRIAD	B3RI98	B3RNB0	PCI domain-containing protein.	PCI domain-containing protein.	0.999
B3RI98_TRIAD	B3RNH6_TRIAD	B3RI98	B3RNH6	PCI domain-containing protein.	Proteasome subunit beta.	0.995
B3RI98_TRIAD	B3RNU6_TRIAD	B3RI98	B3RNU6	PCI domain-containing protein.	Proteasome subunit beta.	0.997
B3RI98_TRIAD	B3RNW4_TRIAD	B3RI98	B3RNW4	PCI domain-containing protein.	Uncharacterized protein.	0.988
B3RI98_TRIAD	B3RQH7_TRIAD	B3RI98	B3RQH7	PCI domain-containing protein.	Uncharacterized protein.	0.996
B3RI98_TRIAD	B3RQI2_TRIAD	B3RI98	B3RQI2	PCI domain-containing protein.	PA28_beta domain-containing protein.	0.822
B3RI98_TRIAD	B3RRY1_TRIAD	B3RI98	B3RRY1	PCI domain-containing protein.	MPN domain-containing protein.	0.947
B3RI98_TRIAD	B3RTI1_TRIAD	B3RI98	B3RTI1	PCI domain-containing protein.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.998
B3RI98_TRIAD	B3RTW1_TRIAD	B3RI98	B3RTW1	PCI domain-containing protein.	Uncharacterized protein.	0.909
B3RI98_TRIAD	B3RVM5_TRIAD	B3RI98	B3RVM5	PCI domain-containing protein.	Proteasome subunit beta.	0.987
B3RI98_TRIAD	B3RVP1_TRIAD	B3RI98	B3RVP1	PCI domain-containing protein.	MPN domain-containing protein.	0.999
B3RI98_TRIAD	B3RW83_TRIAD	B3RI98	B3RW83	PCI domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
B3RI98_TRIAD	B3RWL9_TRIAD	B3RI98	B3RWL9	PCI domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.994