(10 nodes) Mixed, incl. Actin filament depolymerization, and Fimbrin/Plastin network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RIX1_TRIAD	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (128 aa)
	B3RTX5_TRIAD	Uncharacterized protein. (1017 aa)
	B3S078_TRIAD	WD_REPEATS_REGION domain-containing protein. (231 aa)
	B3S079_TRIAD	WD_REPEATS_REGION domain-containing protein. (353 aa)
	B3S0K8_TRIAD	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (140 aa)
	B3S128_TRIAD	Adenylyl cyclase-associated protein; Belongs to the CAP family. (441 aa)
	B3S5U5_TRIAD	Uncharacterized protein. (645 aa)
	B3S5U7_TRIAD	Uncharacterized protein. (616 aa)
	B3S8G4_TRIAD	Uncharacterized protein. (469 aa)
	actin	Actin. (376 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RIX1_TRIAD	B3RTX5_TRIAD	B3RIX1	B3RTX5	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Uncharacterized protein.	0.488
B3RIX1_TRIAD	B3S0K8_TRIAD	B3RIX1	B3S0K8	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.624
B3RIX1_TRIAD	B3S128_TRIAD	B3RIX1	B3S128	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.724
B3RIX1_TRIAD	actin	B3RIX1	Q7YTV5	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Actin.	0.485
B3RTX5_TRIAD	B3RIX1_TRIAD	B3RTX5	B3RIX1	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.488
B3RTX5_TRIAD	B3S078_TRIAD	B3RTX5	B3S078	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.611
B3RTX5_TRIAD	B3S079_TRIAD	B3RTX5	B3S079	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.611
B3RTX5_TRIAD	B3S128_TRIAD	B3RTX5	B3S128	Uncharacterized protein.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.811
B3RTX5_TRIAD	B3S8G4_TRIAD	B3RTX5	B3S8G4	Uncharacterized protein.	Uncharacterized protein.	0.491
B3RTX5_TRIAD	actin	B3RTX5	Q7YTV5	Uncharacterized protein.	Actin.	0.456
B3S078_TRIAD	B3RTX5_TRIAD	B3S078	B3RTX5	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.611
B3S078_TRIAD	B3S079_TRIAD	B3S078	B3S079	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.935
B3S078_TRIAD	B3S0K8_TRIAD	B3S078	B3S0K8	WD_REPEATS_REGION domain-containing protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.781
B3S078_TRIAD	B3S128_TRIAD	B3S078	B3S128	WD_REPEATS_REGION domain-containing protein.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.656
B3S078_TRIAD	actin	B3S078	Q7YTV5	WD_REPEATS_REGION domain-containing protein.	Actin.	0.548
B3S079_TRIAD	B3RTX5_TRIAD	B3S079	B3RTX5	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.611
B3S079_TRIAD	B3S078_TRIAD	B3S079	B3S078	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.935
B3S079_TRIAD	B3S0K8_TRIAD	B3S079	B3S0K8	WD_REPEATS_REGION domain-containing protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.781
B3S079_TRIAD	B3S128_TRIAD	B3S079	B3S128	WD_REPEATS_REGION domain-containing protein.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.656
B3S079_TRIAD	actin	B3S079	Q7YTV5	WD_REPEATS_REGION domain-containing protein.	Actin.	0.548