(38 nodes) Telomere maintenance network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3S048_TRIAD	Poly [ADP-ribose] polymerase. (451 aa)
	B3RX95_TRIAD	Uncharacterized protein. (582 aa)
	B3RWW9_TRIAD	G-patch domain-containing protein. (272 aa)
	B3RV84_TRIAD	BRCT domain-containing protein. (528 aa)
	B3RUB9_TRIAD	Uncharacterized protein. (156 aa)
	B3RTU2_TRIAD	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (454 aa)
	B3RSS6_TRIAD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1095 aa)
	B3RSS5_TRIAD	Predicted protein. (1281 aa)
	B3RSA2_TRIAD	Predicted protein. (1491 aa)
	B3RQE9_TRIAD	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	B3RQ94_TRIAD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4042 aa)
	B3RPZ5_TRIAD	HMG box domain-containing protein. (90 aa)
	B3RPH6_TRIAD	Telomere_reg-2 domain-containing protein. (713 aa)
	B3RPD8_TRIAD	Lactamase_B domain-containing protein. (306 aa)
	B3RMC7_TRIAD	DRMBL domain-containing protein. (440 aa)
	B3RJ62_TRIAD	Uncharacterized protein. (725 aa)
	B3RHX3_TRIAD	Uncharacterized protein. (2435 aa)
	B3SEU1_TRIAD	Rep-A_N domain-containing protein. (218 aa)
	B3SAG2_TRIAD	Uncharacterized protein. (1395 aa)
	B3SBI2_TRIAD	Uncharacterized protein. (619 aa)
	B3SCD9_TRIAD	Uncharacterized protein. (199 aa)
	B3SCJ1_TRIAD	Uncharacterized protein. (265 aa)
	B3SDE2_TRIAD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1725 aa)
	B3S9Y9_TRIAD	Ku domain-containing protein. (784 aa)
	B3S8X5_TRIAD	DRMBL domain-containing protein. (375 aa)
	B3S8R6_TRIAD	Uncharacterized protein. (55 aa)
	B3S8C6_TRIAD	SMC_N domain-containing protein. (873 aa)
	B3S8C5_TRIAD	OB domain-containing protein. (313 aa)
	B3S8C3_TRIAD	SMC_N domain-containing protein. (951 aa)
	B3S8B8_TRIAD	FHA domain-containing protein. (399 aa)
	B3S7P8_TRIAD	WD_REPEATS_REGION domain-containing protein. (422 aa)
	B3S6T7_TRIAD	Uncharacterized protein; Belongs to the CGI121/TPRKB family. (213 aa)
	B3S6C0_TRIAD	Helicase ATP-binding domain-containing protein. (995 aa)
	B3S5Q9_TRIAD	Poly [ADP-ribose] polymerase. (128 aa)
	B3S577_TRIAD	Uncharacterized protein. (2314 aa)
	B3S571_TRIAD	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (556 aa)
	B3S2Q7_TRIAD	Helicase ATP-binding domain-containing protein. (702 aa)
	B3S0A5_TRIAD	Uncharacterized protein. (240 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RHX3_TRIAD	B3S2Q7_TRIAD	B3RHX3	B3S2Q7	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.465
B3RHX3_TRIAD	B3S6C0_TRIAD	B3RHX3	B3S6C0	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.465
B3RJ62_TRIAD	B3RQE9_TRIAD	B3RJ62	B3RQE9	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.664
B3RJ62_TRIAD	B3RSS5_TRIAD	B3RJ62	B3RSS5	Uncharacterized protein.	Predicted protein.	0.795
B3RJ62_TRIAD	B3RSS6_TRIAD	B3RJ62	B3RSS6	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.795
B3RJ62_TRIAD	B3RTU2_TRIAD	B3RJ62	B3RTU2	Uncharacterized protein.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.856
B3RJ62_TRIAD	B3RV84_TRIAD	B3RJ62	B3RV84	Uncharacterized protein.	BRCT domain-containing protein.	0.590
B3RJ62_TRIAD	B3S2Q7_TRIAD	B3RJ62	B3S2Q7	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.562
B3RJ62_TRIAD	B3S571_TRIAD	B3RJ62	B3S571	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.807
B3RJ62_TRIAD	B3S6C0_TRIAD	B3RJ62	B3S6C0	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.562
B3RJ62_TRIAD	B3S8C3_TRIAD	B3RJ62	B3S8C3	Uncharacterized protein.	SMC_N domain-containing protein.	0.450
B3RJ62_TRIAD	B3S8C5_TRIAD	B3RJ62	B3S8C5	Uncharacterized protein.	OB domain-containing protein.	0.609
B3RJ62_TRIAD	B3S8C6_TRIAD	B3RJ62	B3S8C6	Uncharacterized protein.	SMC_N domain-containing protein.	0.450
B3RJ62_TRIAD	B3S9Y9_TRIAD	B3RJ62	B3S9Y9	Uncharacterized protein.	Ku domain-containing protein.	0.700
B3RJ62_TRIAD	B3SBI2_TRIAD	B3RJ62	B3SBI2	Uncharacterized protein.	Uncharacterized protein.	0.798
B3RJ62_TRIAD	B3SCJ1_TRIAD	B3RJ62	B3SCJ1	Uncharacterized protein.	Uncharacterized protein.	0.497
B3RJ62_TRIAD	B3SDE2_TRIAD	B3RJ62	B3SDE2	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.865
B3RJ62_TRIAD	B3SEU1_TRIAD	B3RJ62	B3SEU1	Uncharacterized protein.	Rep-A_N domain-containing protein.	0.807
B3RMC7_TRIAD	B3RQ94_TRIAD	B3RMC7	B3RQ94	DRMBL domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.975
B3RMC7_TRIAD	B3RTU2_TRIAD	B3RMC7	B3RTU2	DRMBL domain-containing protein.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.645