(42 nodes) DNA integrity checkpoint signaling network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RQE9_TRIAD	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	B3RII6_TRIAD	Uncharacterized protein. (457 aa)
	B3RJK5_TRIAD	Uncharacterized protein. (280 aa)
	B3RJT7_TRIAD	Uncharacterized protein. (909 aa)
	B3RJU4_TRIAD	Uncharacterized protein. (290 aa)
	B3RKP6_TRIAD	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (189 aa)
	B3RL12_TRIAD	Uncharacterized protein. (1385 aa)
	B3RL41_TRIAD	Uncharacterized protein. (205 aa)
	B3RL42_TRIAD	Uncharacterized protein. (314 aa)
	B3RMJ6_TRIAD	Uncharacterized protein. (137 aa)
	B3RPI9_TRIAD	Uncharacterized protein. (949 aa)
	B3RPL5_TRIAD	Uncharacterized protein. (1339 aa)
	B3RPR1_TRIAD	Uncharacterized protein. (1207 aa)
	B3RPY5_TRIAD	Uncharacterized protein. (401 aa)
	B3RPY9_TRIAD	Uncharacterized protein. (497 aa)
	B3RQ94_TRIAD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4042 aa)
	B3RRY3_TRIAD	Predicted protein. (275 aa)
	B3RS42_TRIAD	AAA domain-containing protein. (369 aa)
	B3RSI5_TRIAD	Predicted protein. (1069 aa)
	B3RSK0_TRIAD	Predicted protein. (1507 aa)
	B3RSS5_TRIAD	Predicted protein. (1281 aa)
	B3RSS6_TRIAD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1095 aa)
	B3RTH4_TRIAD	Uncharacterized protein. (1334 aa)
	B3RTR1_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (470 aa)
	B3RTT5_TRIAD	Uncharacterized protein. (409 aa)
	B3RTU2_TRIAD	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (454 aa)
	B3RV84_TRIAD	BRCT domain-containing protein. (528 aa)
	B3RZF1_TRIAD	F-box domain-containing protein. (415 aa)
	B3RZF7_TRIAD	F-box domain-containing protein. (393 aa)
	B3S114_TRIAD	Uncharacterized protein. (373 aa)
	B3S2J9_TRIAD	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (783 aa)
	B3S2V8_TRIAD	Uncharacterized protein. (264 aa)
	B3S516_TRIAD	WD_REPEATS_REGION domain-containing protein. (499 aa)
	B3S534_TRIAD	Protein kinase domain-containing protein. (273 aa)
	B3S9F4_TRIAD	Uncharacterized protein. (525 aa)
	B3S9Y7_TRIAD	Uncharacterized protein. (151 aa)
	B3SAF8_TRIAD	ERCC4 domain-containing protein. (480 aa)
	B3SAM4_TRIAD	Uncharacterized protein. (374 aa)
	B3SCL0_TRIAD	U1-type domain-containing protein. (301 aa)
	B3SCN0_TRIAD	WD_REPEATS_REGION domain-containing protein. (513 aa)
	B3SDE2_TRIAD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1725 aa)
	B3SE35_TRIAD	Uncharacterized protein. (130 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RII6_TRIAD	B3RJK5_TRIAD	B3RII6	B3RJK5	Uncharacterized protein.	Uncharacterized protein.	0.982
B3RII6_TRIAD	B3RJT7_TRIAD	B3RII6	B3RJT7	Uncharacterized protein.	Uncharacterized protein.	0.686
B3RII6_TRIAD	B3RKP6_TRIAD	B3RII6	B3RKP6	Uncharacterized protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.792
B3RII6_TRIAD	B3RPI9_TRIAD	B3RII6	B3RPI9	Uncharacterized protein.	Uncharacterized protein.	0.646
B3RII6_TRIAD	B3RPL5_TRIAD	B3RII6	B3RPL5	Uncharacterized protein.	Uncharacterized protein.	0.911
B3RII6_TRIAD	B3RPR1_TRIAD	B3RII6	B3RPR1	Uncharacterized protein.	Uncharacterized protein.	0.500
B3RII6_TRIAD	B3RQE9_TRIAD	B3RII6	B3RQE9	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.992
B3RII6_TRIAD	B3RS42_TRIAD	B3RII6	B3RS42	Uncharacterized protein.	AAA domain-containing protein.	0.471
B3RII6_TRIAD	B3RSK0_TRIAD	B3RII6	B3RSK0	Uncharacterized protein.	Predicted protein.	0.882
B3RII6_TRIAD	B3RSS5_TRIAD	B3RII6	B3RSS5	Uncharacterized protein.	Predicted protein.	0.863
B3RII6_TRIAD	B3RSS6_TRIAD	B3RII6	B3RSS6	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.863
B3RII6_TRIAD	B3RTH4_TRIAD	B3RII6	B3RTH4	Uncharacterized protein.	Uncharacterized protein.	0.471
B3RII6_TRIAD	B3RTR1_TRIAD	B3RII6	B3RTR1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.897
B3RII6_TRIAD	B3RTU2_TRIAD	B3RII6	B3RTU2	Uncharacterized protein.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.816
B3RII6_TRIAD	B3RV84_TRIAD	B3RII6	B3RV84	Uncharacterized protein.	BRCT domain-containing protein.	0.795
B3RII6_TRIAD	B3S114_TRIAD	B3RII6	B3S114	Uncharacterized protein.	Uncharacterized protein.	0.442
B3RII6_TRIAD	B3S534_TRIAD	B3RII6	B3S534	Uncharacterized protein.	Protein kinase domain-containing protein.	0.784
B3RII6_TRIAD	B3SAF8_TRIAD	B3RII6	B3SAF8	Uncharacterized protein.	ERCC4 domain-containing protein.	0.633
B3RII6_TRIAD	B3SAM4_TRIAD	B3RII6	B3SAM4	Uncharacterized protein.	Uncharacterized protein.	0.997
B3RII6_TRIAD	B3SCN0_TRIAD	B3RII6	B3SCN0	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.466