(56 nodes) Regulation of MAPK cascade network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RN94_TRIAD	DNL-type domain-containing protein. (50 aa)
	B3RN96_TRIAD	PPM-type phosphatase domain-containing protein. (354 aa)
	B3RNW2_TRIAD	Uncharacterized protein. (534 aa)
	B3S3C3_TRIAD	Rhodanese domain-containing protein. (142 aa)
	B3S6A2_TRIAD	Protein kinase domain-containing protein. (865 aa)
	B3S8T8_TRIAD	WD_REPEATS_REGION domain-containing protein. (321 aa)
	B3SA46_TRIAD	Uncharacterized protein. (467 aa)
	B3SAJ6_TRIAD	Uncharacterized protein. (160 aa)
	B3SB04_TRIAD	Uncharacterized protein. (315 aa)
	B3SB05_TRIAD	Uncharacterized protein. (301 aa)
	B3SBI7_TRIAD	RING-type domain-containing protein. (98 aa)
	B3SBY9_TRIAD	Uncharacterized protein. (372 aa)
	B3SCV0_TRIAD	Sortilin. (875 aa)
	B3RP35_TRIAD	Peptidyl-prolyl cis-trans isomerase. (153 aa)
	B3RPC5_TRIAD	UDENN FLCN/SMCR8-type domain-containing protein. (406 aa)
	B3RQ19_TRIAD	Uncharacterized protein. (862 aa)
	B3RRA4_TRIAD	Predicted protein. (897 aa)
	B3RRD1_TRIAD	IGFBP N-terminal domain-containing protein. (243 aa)
	B3RRG7_TRIAD	Uncharacterized protein. (564 aa)
	B3RRM5_TRIAD	Protein kinase domain-containing protein. (1324 aa)
	B3RRP4_TRIAD	SH3 domain-containing protein. (497 aa)
	B3RUW1_TRIAD	Uncharacterized protein. (299 aa)
	B3RVV8_TRIAD	Uncharacterized protein. (295 aa)
	B3RWV2_TRIAD	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (177 aa)
	B3RXM1_TRIAD	Uncharacterized protein. (328 aa)
	B3RXM2_TRIAD	RH1 domain-containing protein. (150 aa)
	B3RXR4_TRIAD	Uncharacterized protein. (902 aa)
	B3RY08_TRIAD	Protein kinase domain-containing protein. (586 aa)
	B3RY68_TRIAD	ATG11 domain-containing protein. (1041 aa)
	B3RYF9_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (306 aa)
	B3RYH8_TRIAD	Uncharacterized protein. (167 aa)
	B3RYQ8_TRIAD	Protein kinase domain-containing protein. (336 aa)
	B3RYT1_TRIAD	Uncharacterized protein. (318 aa)
	B3RYY5_TRIAD	Uncharacterized protein. (417 aa)
	B3RYY7_TRIAD	Uncharacterized protein. (424 aa)
	B3S0C8_TRIAD	Aida_C2 domain-containing protein. (152 aa)
	B3S134_TRIAD	J domain-containing protein. (269 aa)
	B3S1A6_TRIAD	Uncharacterized protein. (167 aa)
	B3S2H2_TRIAD	Uncharacterized protein. (218 aa)
	B3S2H3_TRIAD	Uncharacterized protein. (204 aa)
	B3S2M0_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	B3S339_TRIAD	Sortilin. (815 aa)
	B3S340_TRIAD	Sortilin. (490 aa)
	B3S3C2_TRIAD	Uncharacterized protein. (138 aa)
	B3RIR1_TRIAD	Uncharacterized protein. (400 aa)
	B3RIV8_TRIAD	Uncharacterized protein. (556 aa)
	B3RJ86_TRIAD	Fork-head domain-containing protein. (90 aa)
	B3RJH9_TRIAD	Uncharacterized protein. (152 aa)
	B3RKY8_TRIAD	Protein kinase domain-containing protein. (440 aa)
	B3RKZ6_TRIAD	UDENN domain-containing protein. (1227 aa)
	B3RKZ7_TRIAD	UDENN domain-containing protein. (282 aa)
	B3RL95_TRIAD	Uncharacterized protein. (129 aa)
	B3RLK4_TRIAD	Uncharacterized protein. (168 aa)
	B3RM24_TRIAD	Uncharacterized protein. (885 aa)
	B3RM32_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (428 aa)
	B3RMU0_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (268 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RIV8_TRIAD	B3RRA4_TRIAD	B3RIV8	B3RRA4	Uncharacterized protein.	Predicted protein.	0.556
B3RIV8_TRIAD	B3RVV8_TRIAD	B3RIV8	B3RVV8	Uncharacterized protein.	Uncharacterized protein.	0.463
B3RKY8_TRIAD	B3RM32_TRIAD	B3RKY8	B3RM32	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.522
B3RKZ6_TRIAD	B3RKZ7_TRIAD	B3RKZ6	B3RKZ7	UDENN domain-containing protein.	UDENN domain-containing protein.	0.941
B3RKZ7_TRIAD	B3RKZ6_TRIAD	B3RKZ7	B3RKZ6	UDENN domain-containing protein.	UDENN domain-containing protein.	0.941
B3RM32_TRIAD	B3RKY8_TRIAD	B3RM32	B3RKY8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.522
B3RMU0_TRIAD	B3RN96_TRIAD	B3RMU0	B3RN96	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	PPM-type phosphatase domain-containing protein.	0.527
B3RMU0_TRIAD	B3RYF9_TRIAD	B3RMU0	B3RYF9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.561
B3RMU0_TRIAD	B3SBI7_TRIAD	B3RMU0	B3SBI7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.633
B3RN96_TRIAD	B3RMU0_TRIAD	B3RN96	B3RMU0	PPM-type phosphatase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.527
B3RN96_TRIAD	B3RYY7_TRIAD	B3RN96	B3RYY7	PPM-type phosphatase domain-containing protein.	Uncharacterized protein.	0.470
B3RN96_TRIAD	B3SBI7_TRIAD	B3RN96	B3SBI7	PPM-type phosphatase domain-containing protein.	RING-type domain-containing protein.	0.996
B3RPC5_TRIAD	B3RYH8_TRIAD	B3RPC5	B3RYH8	UDENN FLCN/SMCR8-type domain-containing protein.	Uncharacterized protein.	0.802
B3RQ19_TRIAD	B3RRA4_TRIAD	B3RQ19	B3RRA4	Uncharacterized protein.	Predicted protein.	0.465
B3RQ19_TRIAD	B3RYY5_TRIAD	B3RQ19	B3RYY5	Uncharacterized protein.	Uncharacterized protein.	0.430
B3RRA4_TRIAD	B3RIV8_TRIAD	B3RRA4	B3RIV8	Predicted protein.	Uncharacterized protein.	0.556
B3RRA4_TRIAD	B3RQ19_TRIAD	B3RRA4	B3RQ19	Predicted protein.	Uncharacterized protein.	0.465
B3RRA4_TRIAD	B3RVV8_TRIAD	B3RRA4	B3RVV8	Predicted protein.	Uncharacterized protein.	0.639
B3RRA4_TRIAD	B3RY68_TRIAD	B3RRA4	B3RY68	Predicted protein.	ATG11 domain-containing protein.	0.823
B3RRA4_TRIAD	B3RYY5_TRIAD	B3RRA4	B3RYY5	Predicted protein.	Uncharacterized protein.	0.428