(16 nodes) Membrane raft network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RUE4_TRIAD	Uncharacterized protein. (715 aa)
	B3RYH8_TRIAD	Uncharacterized protein. (167 aa)
	B3RWV2_TRIAD	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (177 aa)
	B3S0V5_TRIAD	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (325 aa)
	B3S496_TRIAD	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (426 aa)
	B3S497_TRIAD	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (426 aa)
	B3S4V2_TRIAD	Uncharacterized protein. (169 aa)
	B3S858_TRIAD	Endo/exonuclease/phosphatase domain-containing protein. (284 aa)
	B3SEH1_TRIAD	PHB domain-containing protein. (314 aa)
	B3SFP1_TRIAD	Hydrolase_4 domain-containing protein. (228 aa)
	B3RMC8_TRIAD	Uncharacterized protein. (334 aa)
	B3RN00_TRIAD	Robl_LC7 domain-containing protein. (139 aa)
	B3RP39_TRIAD	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (434 aa)
	B3RQY1_TRIAD	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	B3RSS8_TRIAD	PHB domain-containing protein. (411 aa)
	B3RTT8_TRIAD	Uncharacterized protein. (431 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RN00_TRIAD	B3RYH8_TRIAD	B3RN00	B3RYH8	Robl_LC7 domain-containing protein.	Uncharacterized protein.	0.999
B3RN00_TRIAD	B3S4V2_TRIAD	B3RN00	B3S4V2	Robl_LC7 domain-containing protein.	Uncharacterized protein.	0.999
B3RP39_TRIAD	B3RWV2_TRIAD	B3RP39	B3RWV2	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.488
B3RP39_TRIAD	B3S496_TRIAD	B3RP39	B3S496	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.557
B3RP39_TRIAD	B3S497_TRIAD	B3RP39	B3S497	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.556
B3RWV2_TRIAD	B3RP39_TRIAD	B3RWV2	B3RP39	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.488
B3RWV2_TRIAD	B3S496_TRIAD	B3RWV2	B3S496	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.488
B3RWV2_TRIAD	B3S497_TRIAD	B3RWV2	B3S497	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.488
B3RYH8_TRIAD	B3RN00_TRIAD	B3RYH8	B3RN00	Uncharacterized protein.	Robl_LC7 domain-containing protein.	0.999
B3RYH8_TRIAD	B3S4V2_TRIAD	B3RYH8	B3S4V2	Uncharacterized protein.	Uncharacterized protein.	0.999
B3S496_TRIAD	B3RP39_TRIAD	B3S496	B3RP39	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.557
B3S496_TRIAD	B3RWV2_TRIAD	B3S496	B3RWV2	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.488
B3S496_TRIAD	B3S497_TRIAD	B3S496	B3S497	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.544
B3S497_TRIAD	B3RP39_TRIAD	B3S497	B3RP39	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.556
B3S497_TRIAD	B3RWV2_TRIAD	B3S497	B3RWV2	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.488
B3S497_TRIAD	B3S496_TRIAD	B3S497	B3S496	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.544
B3S4V2_TRIAD	B3RN00_TRIAD	B3S4V2	B3RN00	Uncharacterized protein.	Robl_LC7 domain-containing protein.	0.999
B3S4V2_TRIAD	B3RYH8_TRIAD	B3S4V2	B3RYH8	Uncharacterized protein.	Uncharacterized protein.	0.999