(49 nodes) Negative regulation of cell differentiation network (Trichoplax adhaerens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3SDQ0_TRIAD	Anti_prolifrtn domain-containing protein. (96 aa)
	B3SDC6_TRIAD	Uncharacterized protein. (102 aa)
	B3SD46_TRIAD	PCM1_C domain-containing protein. (1371 aa)
	B3SCV0_TRIAD	Sortilin. (875 aa)
	B3SBY2_TRIAD	Uncharacterized protein; Belongs to the heat shock protein 70 family. (603 aa)
	B3S8U5_TRIAD	Homeobox domain-containing protein. (62 aa)
	B3S7L6_TRIAD	Uncharacterized protein. (820 aa)
	B3S625_TRIAD	Uncharacterized protein. (277 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (137 aa)
	B3S340_TRIAD	Sortilin. (490 aa)
	B3S339_TRIAD	Sortilin. (815 aa)
	B3S2A4_TRIAD	Protein kinase domain-containing protein. (301 aa)
	B3S238_TRIAD	BHLH domain-containing protein. (321 aa)
	B3S1A6_TRIAD	Uncharacterized protein. (167 aa)
	B3RZZ0_TRIAD	Uncharacterized protein. (134 aa)
	B3RZW1_TRIAD	Expressed protein. (246 aa)
	B3RZS6_TRIAD	Uncharacterized protein. (576 aa)
	B3RZQ0_TRIAD	Uncharacterized protein. (1269 aa)
	B3RZ69_TRIAD	c-SKI_SMAD_bind domain-containing protein. (213 aa)
	B3RYI5_TRIAD	BHLH domain-containing protein. (494 aa)
	B3RY87_TRIAD	Predicted protein. (243 aa)
	B3RY69_TRIAD	Endo/exonuclease/phosphatase domain-containing protein. (267 aa)
	B3RWV2_TRIAD	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (177 aa)
	B3RW22_TRIAD	BHLH domain-containing protein. (63 aa)
	B3RW21_TRIAD	Predicted protein. (234 aa)
	B3RVR8_TRIAD	IRF tryptophan pentad repeat domain-containing protein. (315 aa)
	B3RTM8_TRIAD	Uncharacterized protein. (593 aa)
	B3RSW2_TRIAD	Uncharacterized protein. (369 aa)
	B3RRA4_TRIAD	Predicted protein. (897 aa)
	B3RR15_TRIAD	Uncharacterized protein. (620 aa)
	B3RQN6_TRIAD	Uncharacterized protein. (296 aa)
	B3RQE7_TRIAD	Uncharacterized protein; Belongs to the semaphorin family. (1192 aa)
	B3RQE3_TRIAD	Sema domain-containing protein. (1065 aa)
	B3RQE2_TRIAD	Uncharacterized protein. (168 aa)
	B3RPQ7_TRIAD	Uncharacterized protein. (594 aa)
	B3RPC5_TRIAD	UDENN FLCN/SMCR8-type domain-containing protein. (406 aa)
	B3RNW3_TRIAD	RING-type domain-containing protein. (485 aa)
	B3RNG6_TRIAD	Uncharacterized protein. (444 aa)
	B3RMU3_TRIAD	Uncharacterized protein. (234 aa)
	B3RMC8_TRIAD	Uncharacterized protein. (334 aa)
	B3RL05_TRIAD	PKS_ER domain-containing protein. (349 aa)
	B3RKR8_TRIAD	Homeobox domain-containing protein. (272 aa)
	B3RJA5_TRIAD	TPR_REGION domain-containing protein. (938 aa)
	B3RJA4_TRIAD	TPR_REGION domain-containing protein. (911 aa)
	B3RIK5_TRIAD	ANK_REP_REGION domain-containing protein. (184 aa)
	B3RIH0_TRIAD	ETS domain-containing protein. (107 aa)
	B3RI36_TRIAD	Mothers against decapentaplegic homolog. (298 aa)
	B3RI08_TRIAD	Uncharacterized protein. (640 aa)
	B3SFG9_TRIAD	Uncharacterized protein. (138 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RI36_TRIAD	B3RZ69_TRIAD	B3RI36	B3RZ69	Mothers against decapentaplegic homolog.	c-SKI_SMAD_bind domain-containing protein.	0.624
B3RIH0_TRIAD	B3RW21_TRIAD	B3RIH0	B3RW21	ETS domain-containing protein.	Predicted protein.	0.459
B3RIH0_TRIAD	B3RW22_TRIAD	B3RIH0	B3RW22	ETS domain-containing protein.	BHLH domain-containing protein.	0.486
B3RJA4_TRIAD	B3RJA5_TRIAD	B3RJA4	B3RJA5	TPR_REGION domain-containing protein.	TPR_REGION domain-containing protein.	0.544
B3RJA4_TRIAD	B3RNG6_TRIAD	B3RJA4	B3RNG6	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.581
B3RJA4_TRIAD	B3S625_TRIAD	B3RJA4	B3S625	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.999
B3RJA5_TRIAD	B3RJA4_TRIAD	B3RJA5	B3RJA4	TPR_REGION domain-containing protein.	TPR_REGION domain-containing protein.	0.544
B3RJA5_TRIAD	B3RNG6_TRIAD	B3RJA5	B3RNG6	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.581
B3RJA5_TRIAD	B3S625_TRIAD	B3RJA5	B3S625	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.999
B3RNG6_TRIAD	B3RJA4_TRIAD	B3RNG6	B3RJA4	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.581
B3RNG6_TRIAD	B3RJA5_TRIAD	B3RNG6	B3RJA5	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.581
B3RNG6_TRIAD	B3S625_TRIAD	B3RNG6	B3S625	Uncharacterized protein.	Uncharacterized protein.	0.440
B3RW21_TRIAD	B3RIH0_TRIAD	B3RW21	B3RIH0	Predicted protein.	ETS domain-containing protein.	0.459
B3RW22_TRIAD	B3RIH0_TRIAD	B3RW22	B3RIH0	BHLH domain-containing protein.	ETS domain-containing protein.	0.486
B3RZ69_TRIAD	B3RI36_TRIAD	B3RZ69	B3RI36	c-SKI_SMAD_bind domain-containing protein.	Mothers against decapentaplegic homolog.	0.624
B3RZS6_TRIAD	B3SBY2_TRIAD	B3RZS6	B3SBY2	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.447
B3RZS6_TRIAD	B3SFG9_TRIAD	B3RZS6	B3SFG9	Uncharacterized protein.	Uncharacterized protein.	0.447
B3S625_TRIAD	B3RJA4_TRIAD	B3S625	B3RJA4	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.999
B3S625_TRIAD	B3RJA5_TRIAD	B3S625	B3RJA5	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.999
B3S625_TRIAD	B3RNG6_TRIAD	B3S625	B3RNG6	Uncharacterized protein.	Uncharacterized protein.	0.440