(19 nodes) Homeostasis of number of cells network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RQB4_TRIAD	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (282 aa)
	B3RNW3_TRIAD	RING-type domain-containing protein. (485 aa)
	B3S7T2_TRIAD	Phospholipase A(2). (127 aa)
	B3S7L6_TRIAD	Uncharacterized protein. (820 aa)
	B3S6L0_TRIAD	Uncharacterized protein. (227 aa)
	B3S4C8_TRIAD	WD_REPEATS_REGION domain-containing protein. (484 aa)
	B3S0U3_TRIAD	Lactamase_B domain-containing protein. (323 aa)
	B3S0R5_TRIAD	Uncharacterized protein. (423 aa)
	B3RYU5_TRIAD	Helicase ATP-binding domain-containing protein. (720 aa)
	B3RXY6_TRIAD	Predicted protein. (363 aa)
	B3RWM9_TRIAD	Uncharacterized protein. (661 aa)
	B3RUI1_TRIAD	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (556 aa)
	B3SCQ2_TRIAD	Uncharacterized protein. (1171 aa)
	B3SE98_TRIAD	Phospholipase A(2). (111 aa)
	B3SBV8_TRIAD	Uncharacterized protein. (405 aa)
	B3SBY2_TRIAD	Uncharacterized protein; Belongs to the heat shock protein 70 family. (603 aa)
	B3SFG9_TRIAD	Uncharacterized protein. (138 aa)
	B3RJ74_TRIAD	Uncharacterized protein. (147 aa)
	B3RN94_TRIAD	DNL-type domain-containing protein. (50 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RQB4_TRIAD	B3RUI1_TRIAD	B3RQB4	B3RUI1	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.463
B3RUI1_TRIAD	B3RQB4_TRIAD	B3RUI1	B3RQB4	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.	0.463
B3RUI1_TRIAD	B3RXY6_TRIAD	B3RUI1	B3RXY6	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	Predicted protein.	0.576
B3RXY6_TRIAD	B3RUI1_TRIAD	B3RXY6	B3RUI1	Predicted protein.	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.576
B3S7T2_TRIAD	B3SE98_TRIAD	B3S7T2	B3SE98	Phospholipase A(2).	Phospholipase A(2).	0.901
B3SE98_TRIAD	B3S7T2_TRIAD	B3SE98	B3S7T2	Phospholipase A(2).	Phospholipase A(2).	0.901