(45 nodes) Toll Like Receptor 7/8 (TLR7/8) Cascade network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RUZ6_TRIAD	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (156 aa)
	B3RVJ9_TRIAD	TPR_REGION domain-containing protein. (107 aa)
	B3RVY6_TRIAD	Uncharacterized protein. (762 aa)
	B3RW79_TRIAD	Uncharacterized protein. (594 aa)
	B3RWI7_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (261 aa)
	B3RWM9_TRIAD	Uncharacterized protein. (661 aa)
	B3RWN3_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa)
	B3RYE5_TRIAD	C3H1-type domain-containing protein. (218 aa)
	B3S086_TRIAD	Uncharacterized protein. (403 aa)
	B3S0L1_TRIAD	Uncharacterized protein. (410 aa)
	B3S0X9_TRIAD	Predicted protein. (642 aa)
	B3S0Y3_TRIAD	BZIP domain-containing protein. (272 aa)
	B3S187_TRIAD	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (310 aa)
	B3S1G1_TRIAD	Ubiquitin carboxyl-terminal hydrolase. (446 aa)
	B3S3U8_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (270 aa)
	B3S5X7_TRIAD	Uncharacterized protein. (384 aa)
	B3S653_TRIAD	Serine/threonine-protein phosphatase. (310 aa)
	B3S6T0_TRIAD	Mitogen-activated protein kinase. (363 aa)
	B3S8S4_TRIAD	Uncharacterized protein. (414 aa)
	B3S9Q2_TRIAD	Ribosomal protein S6 kinase. (727 aa)
	B3SAM3_TRIAD	Uncharacterized protein. (517 aa)
	B3SBI7_TRIAD	RING-type domain-containing protein. (98 aa)
	B3SC28_TRIAD	Uncharacterized protein. (1068 aa)
	B3SCG5_TRIAD	Ubiquitin-like domain-containing protein. (99 aa)
	B3SCL7_TRIAD	Uncharacterized protein. (206 aa)
	B3SDA2_TRIAD	Protein kinase domain-containing protein. (616 aa)
	B3SDJ1_TRIAD	Uncharacterized protein. (457 aa)
	B3SF52_TRIAD	Uncharacterized protein. (229 aa)
	B3RIS5_TRIAD	LisH domain-containing protein. (1086 aa)
	B3RJY0_TRIAD	Ribosomal protein S6 kinase. (735 aa)
	B3RJY2_TRIAD	Ubiquitin-like domain-containing protein. (165 aa)
	B3RKD5_TRIAD	Predicted protein. (453 aa)
	B3RKL5_TRIAD	Uncharacterized protein. (611 aa)
	B3RKS0_TRIAD	Uncharacterized protein. (769 aa)
	B3RKS5_TRIAD	Uncharacterized protein. (574 aa)
	B3RM75_TRIAD	Uncharacterized protein. (584 aa)
	B3RMU0_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (268 aa)
	B3RN11_TRIAD	Protein kinase domain-containing protein. (307 aa)
	B3RN96_TRIAD	PPM-type phosphatase domain-containing protein. (354 aa)
	B3RNP1_TRIAD	Protein kinase domain-containing protein. (320 aa)
	B3RPX5_TRIAD	ECSIT_Cterm domain-containing protein. (372 aa)
	B3RQF4_TRIAD	Uncharacterized protein. (294 aa)
	B3RR72_TRIAD	KxDL domain-containing protein. (121 aa)
	B3RRN5_TRIAD	Uncharacterized protein. (210 aa)
	B3RVJ8_TRIAD	Uncharacterized protein. (1302 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RIS5_TRIAD	B3S653_TRIAD	B3RIS5	B3S653	LisH domain-containing protein.	Serine/threonine-protein phosphatase.	0.835
B3RJY0_TRIAD	B3RQF4_TRIAD	B3RJY0	B3RQF4	Ribosomal protein S6 kinase.	Uncharacterized protein.	0.839
B3RJY0_TRIAD	B3S187_TRIAD	B3RJY0	B3S187	Ribosomal protein S6 kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.412
B3RJY2_TRIAD	B3RN96_TRIAD	B3RJY2	B3RN96	Ubiquitin-like domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.473
B3RJY2_TRIAD	B3RR72_TRIAD	B3RJY2	B3RR72	Ubiquitin-like domain-containing protein.	KxDL domain-containing protein.	0.655
B3RJY2_TRIAD	B3RUZ6_TRIAD	B3RJY2	B3RUZ6	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.996
B3RJY2_TRIAD	B3RVJ8_TRIAD	B3RJY2	B3RVJ8	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.958
B3RJY2_TRIAD	B3RVJ9_TRIAD	B3RJY2	B3RVJ9	Ubiquitin-like domain-containing protein.	TPR_REGION domain-containing protein.	0.958
B3RJY2_TRIAD	B3RWI7_TRIAD	B3RJY2	B3RWI7	Ubiquitin-like domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.679
B3RJY2_TRIAD	B3S1G1_TRIAD	B3RJY2	B3S1G1	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase.	0.945
B3RJY2_TRIAD	B3S5X7_TRIAD	B3RJY2	B3S5X7	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.901
B3RJY2_TRIAD	B3S653_TRIAD	B3RJY2	B3S653	Ubiquitin-like domain-containing protein.	Serine/threonine-protein phosphatase.	0.653
B3RJY2_TRIAD	B3SBI7_TRIAD	B3RJY2	B3SBI7	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.946
B3RJY2_TRIAD	B3SC28_TRIAD	B3RJY2	B3SC28	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.447
B3RJY2_TRIAD	B3SCG5_TRIAD	B3RJY2	B3SCG5	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.999
B3RJY2_TRIAD	B3SDA2_TRIAD	B3RJY2	B3SDA2	Ubiquitin-like domain-containing protein.	Protein kinase domain-containing protein.	0.686
B3RJY2_TRIAD	B3SDJ1_TRIAD	B3RJY2	B3SDJ1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.901
B3RJY2_TRIAD	B3SF52_TRIAD	B3RJY2	B3SF52	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.447
B3RKD5_TRIAD	B3S653_TRIAD	B3RKD5	B3S653	Predicted protein.	Serine/threonine-protein phosphatase.	0.835
B3RKS0_TRIAD	B3RVY6_TRIAD	B3RKS0	B3RVY6	Uncharacterized protein.	Uncharacterized protein.	0.549