(26 nodes) Translesion synthesis by POLK network (Trichoplax adhaerens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3SDS4_TRIAD	DNA polymerase. (765 aa)
	B3SEU1_TRIAD	Rep-A_N domain-containing protein. (218 aa)
	B3SF45_TRIAD	DNA_pol_B domain-containing protein. (77 aa)
	B3S4I8_TRIAD	AAA domain-containing protein. (315 aa)
	B3RIA2_TRIAD	Uncharacterized protein. (590 aa)
	B3S4Q9_TRIAD	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	B3RWK4_TRIAD	AAA domain-containing protein. (355 aa)
	B3S571_TRIAD	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (556 aa)
	B3S5W0_TRIAD	HORMA domain-containing protein. (215 aa)
	B3RIA3_TRIAD	Uncharacterized protein. (612 aa)
	B3RJY2_TRIAD	Ubiquitin-like domain-containing protein. (165 aa)
	B3RPQ8_TRIAD	Predicted protein. (1416 aa)
	B3RQD9_TRIAD	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1014 aa)
	B3RR72_TRIAD	KxDL domain-containing protein. (121 aa)
	B3RUC9_TRIAD	AAA domain-containing protein. (373 aa)
	B3RS03_TRIAD	UmuC domain-containing protein. (653 aa)
	B3S5X7_TRIAD	Uncharacterized protein. (384 aa)
	B3S7W9_TRIAD	Uncharacterized protein. (448 aa)
	B3S218_TRIAD	BRCT domain-containing protein. (716 aa)
	B3S7X0_TRIAD	Uncharacterized protein. (514 aa)
	B3SCG5_TRIAD	Ubiquitin-like domain-containing protein. (99 aa)
	B3SDJ1_TRIAD	Uncharacterized protein. (457 aa)
	B3SDS0_TRIAD	DNA_pol_B_exo1 domain-containing protein. (240 aa)
	B3SDS1_TRIAD	DNA polymerase. (740 aa)
	B3SDS2_TRIAD	DNA_pol_B_exo1 domain-containing protein. (230 aa)
	B3SDS3_TRIAD	Uncharacterized protein. (55 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RIA2_TRIAD	B3RIA3_TRIAD	B3RIA2	B3RIA3	Uncharacterized protein.	Uncharacterized protein.	0.417
B3RIA3_TRIAD	B3RIA2_TRIAD	B3RIA3	B3RIA2	Uncharacterized protein.	Uncharacterized protein.	0.417
B3RJY2_TRIAD	B3RPQ8_TRIAD	B3RJY2	B3RPQ8	Ubiquitin-like domain-containing protein.	Predicted protein.	0.500
B3RJY2_TRIAD	B3RQD9_TRIAD	B3RJY2	B3RQD9	Ubiquitin-like domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.869
B3RJY2_TRIAD	B3RR72_TRIAD	B3RJY2	B3RR72	Ubiquitin-like domain-containing protein.	KxDL domain-containing protein.	0.655
B3RJY2_TRIAD	B3RS03_TRIAD	B3RJY2	B3RS03	Ubiquitin-like domain-containing protein.	UmuC domain-containing protein.	0.694
B3RJY2_TRIAD	B3RUC9_TRIAD	B3RJY2	B3RUC9	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.659
B3RJY2_TRIAD	B3RWK4_TRIAD	B3RJY2	B3RWK4	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.659
B3RJY2_TRIAD	B3S218_TRIAD	B3RJY2	B3S218	Ubiquitin-like domain-containing protein.	BRCT domain-containing protein.	0.652
B3RJY2_TRIAD	B3S4I8_TRIAD	B3RJY2	B3S4I8	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.659
B3RJY2_TRIAD	B3S4Q9_TRIAD	B3RJY2	B3S4Q9	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.941
B3RJY2_TRIAD	B3S571_TRIAD	B3RJY2	B3S571	Ubiquitin-like domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.510
B3RJY2_TRIAD	B3S5W0_TRIAD	B3RJY2	B3S5W0	Ubiquitin-like domain-containing protein.	HORMA domain-containing protein.	0.654
B3RJY2_TRIAD	B3S5X7_TRIAD	B3RJY2	B3S5X7	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.901
B3RJY2_TRIAD	B3SCG5_TRIAD	B3RJY2	B3SCG5	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.999
B3RJY2_TRIAD	B3SDJ1_TRIAD	B3RJY2	B3SDJ1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.901
B3RJY2_TRIAD	B3SEU1_TRIAD	B3RJY2	B3SEU1	Ubiquitin-like domain-containing protein.	Rep-A_N domain-containing protein.	0.410
B3RPQ8_TRIAD	B3RJY2_TRIAD	B3RPQ8	B3RJY2	Predicted protein.	Ubiquitin-like domain-containing protein.	0.500
B3RPQ8_TRIAD	B3RQD9_TRIAD	B3RPQ8	B3RQD9	Predicted protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.604
B3RPQ8_TRIAD	B3RS03_TRIAD	B3RPQ8	B3RS03	Predicted protein.	UmuC domain-containing protein.	0.577