(44 nodes) FoxO signaling pathway network (Trichoplax adhaerens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B3RI80_TRIAD	Mothers against decapentaplegic homolog. (388 aa)
	B3RIR2_TRIAD	Uncharacterized protein. (606 aa)
	B3RKF7_TRIAD	AMPKBI domain-containing protein. (191 aa)
	B3RLW0_TRIAD	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (322 aa)
	B3RPN1_TRIAD	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
	B3RPP3_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	B3RQ28_TRIAD	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (109 aa)
	B3RQ40_TRIAD	Uncharacterized protein. (1039 aa)
	B3RRM1_TRIAD	G_PROTEIN_RECEP_F3_4 domain-containing protein. (823 aa)
	B3RSG0_TRIAD	WH1 domain-containing protein. (98 aa)
	B3RT01_TRIAD	Uncharacterized protein; Belongs to the cyclin family. (250 aa)
	B3RT03_TRIAD	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (284 aa)
	B3RT05_TRIAD	RING-type domain-containing protein; Belongs to the MDM2/MDM4 family. (458 aa)
	B3RT16_TRIAD	Tyrosine-protein kinase receptor. (449 aa)
	B3RT71_TRIAD	Uncharacterized protein. (291 aa)
	B3RTX9_TRIAD	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
	B3RUV0_TRIAD	Mitogen-activated protein kinase. (360 aa)
	B3RVL5_TRIAD	Uncharacterized protein. (118 aa)
	B3RXC5_TRIAD	SET domain-containing protein. (346 aa)
	B3RXR0_TRIAD	Fork-head domain-containing protein. (148 aa)
	B3RZJ1_TRIAD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1023 aa)
	B3S0A0_TRIAD	Gabarap protein. (117 aa)
	B3S191_TRIAD	Uncharacterized protein; Belongs to the protein kinase superfamily. (472 aa)
	B3S1R2_TRIAD	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
	B3S236_TRIAD	F-box domain-containing protein. (323 aa)
	B3S4A6_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (426 aa)
	B3S4N1_TRIAD	Uncharacterized protein. (351 aa)
	B3S4Z1_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (258 aa)
	B3S523_TRIAD	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
	B3S5R4_TRIAD	Uncharacterized protein. (171 aa)
	B3S5Z8_TRIAD	G_PROTEIN_RECEP_F3_4 domain-containing protein. (792 aa)
	B3S6T0_TRIAD	Mitogen-activated protein kinase. (363 aa)
	B3S755_TRIAD	Serine/threonine-protein kinase PLK. (569 aa)
	B3S7S5_TRIAD	Mothers against decapentaplegic homolog. (525 aa)
	B3S8I9_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (308 aa)
	B3S9G1_TRIAD	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (462 aa)
	B3S9N8_TRIAD	Uncharacterized protein. (1526 aa)
	B3SC13_TRIAD	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (506 aa)
	B3SCA2_TRIAD	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
	B3SCK3_TRIAD	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (319 aa)
	B3SCQ2_TRIAD	Uncharacterized protein. (1171 aa)
	B3SDA2_TRIAD	Protein kinase domain-containing protein. (616 aa)
	B3SDE2_TRIAD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1725 aa)
	B3SFQ5_TRIAD	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (195 aa)

Your Current Organism:

Trichoplax adhaerens

NCBI taxonomy Id: 10228
Other names: T. adhaerens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3RI80_TRIAD	B3RXR0_TRIAD	B3RI80	B3RXR0	Mothers against decapentaplegic homolog.	Fork-head domain-containing protein.	0.573
B3RI80_TRIAD	B3S523_TRIAD	B3RI80	B3S523	Mothers against decapentaplegic homolog.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.931
B3RI80_TRIAD	B3S7S5_TRIAD	B3RI80	B3S7S5	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.985
B3RIR2_TRIAD	B3RXR0_TRIAD	B3RIR2	B3RXR0	Uncharacterized protein.	Fork-head domain-containing protein.	0.478
B3RKF7_TRIAD	B3RT71_TRIAD	B3RKF7	B3RT71	AMPKBI domain-containing protein.	Uncharacterized protein.	0.999
B3RKF7_TRIAD	B3RXR0_TRIAD	B3RKF7	B3RXR0	AMPKBI domain-containing protein.	Fork-head domain-containing protein.	0.913
B3RKF7_TRIAD	B3S1R2_TRIAD	B3RKF7	B3S1R2	AMPKBI domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.998
B3RKF7_TRIAD	B3S4Z1_TRIAD	B3RKF7	B3S4Z1	AMPKBI domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.986
B3RLW0_TRIAD	B3RXR0_TRIAD	B3RLW0	B3RXR0	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Fork-head domain-containing protein.	0.917
B3RLW0_TRIAD	B3S9N8_TRIAD	B3RLW0	B3S9N8	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.481
B3RPN1_TRIAD	B3RXR0_TRIAD	B3RPN1	B3RXR0	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Fork-head domain-containing protein.	0.533
B3RPN1_TRIAD	B3S6T0_TRIAD	B3RPN1	B3S6T0	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Mitogen-activated protein kinase.	0.626
B3RPN1_TRIAD	B3SC13_TRIAD	B3RPN1	B3SC13	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.660
B3RPN1_TRIAD	B3SCK3_TRIAD	B3RPN1	B3SCK3	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.	0.660
B3RPN1_TRIAD	B3SFQ5_TRIAD	B3RPN1	B3SFQ5	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.910
B3RPP3_TRIAD	B3RXR0_TRIAD	B3RPP3	B3RXR0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Fork-head domain-containing protein.	0.903
B3RPP3_TRIAD	B3S755_TRIAD	B3RPP3	B3S755	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase PLK.	0.767
B3RQ28_TRIAD	B3RVL5_TRIAD	B3RQ28	B3RVL5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.835
B3RQ28_TRIAD	B3RXR0_TRIAD	B3RQ28	B3RXR0	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Fork-head domain-containing protein.	0.554
B3RQ28_TRIAD	B3S0A0_TRIAD	B3RQ28	B3S0A0	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Gabarap protein.	0.835