(23 nodes) Butanoate metabolism network (Psychrobacter sp. DABAL43B)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLJ83231.1	enoyl-CoA hydratase; High confidence in function and specificity. (271 aa)
	sdhC	Succinate dehydrogenase, cytochrome b560 subunit; High confidence in function and specificity. (128 aa)
	sdhD	Succinate dehydrogenase, hydrophobic membrane anchor; High confidence in function and specificity. (135 aa)
	sdhA	Succinate dehydrogenase, flavoprotein subunit, FAD dependent oxidoreductase; High confidence in function and specificity; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (616 aa)
	sdhB1	Succinate dehydrogenase/fumarate reductase iron-sulphur protein; High confidence in function and specificity; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa)
	SLJ83545.1	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	mvaB	Hydroxymethylglutaryl-CoA lyase, mitochondrial; High confidence in function and specificity. (306 aa)
	ilvI	Acetolactate synthase isozyme 3 large subunit, biosynthetic, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; High confidence in function and specificity. (608 aa)
	ilvH	Acetolactate synthase isozyme 3 small subunit, ACT domain; High confidence in function and specificity. (165 aa)
	gabD1	Succinate-semialdehyde dehydrogenase [NADP+]; High confidence in function and specificity; Belongs to the aldehyde dehydrogenase family. (504 aa)
	SLJ84335.1	acetyl-CoA acetyltransferase / thiolase, N-terminal domain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
	SLJ84336.1	3-hydroxyacyl-CoA dehydrogenase, NAD binding; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
	sdhB3	Succinate dehydrogenase iron-sulfur subunit; High confidence in function and specificity; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa)
	fadB1	3-hydroxyacyl-CoA dehydrogenase; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family. (731 aa)
	fadA1	acetyl-CoA acetyltransferase, thiolase, alpha-lytic protease prodomain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
	cat1	Acetyl-CoA hydrolase/transferase N-terminal domain; High confidence in function and specificity. (516 aa)
	SLJ84968.1	acetyl-CoA C-acetyltransferase; Thiolase, N-terminal domain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. (548 aa)
	bdhA	3-hydroxybutyrate dehydrogenase, Fungal family of unknown function (DUF1776); High confidence in function and specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
	atoA	3-oxoacid CoA-transferase, subunit B, Cytochrome C and Quinol oxidase polypeptide I; High confidence in function and specificity. (209 aa)
	atoD	3-oxoacid CoA-transferase subunit A; Coenzyme A transferase; High confidence in function and specificity. (237 aa)
	gabD3	Succinate-semialdehyde dehydrogenase (NADP+); Aldehyde dehydrogenase domain, Protein of unknown function (DUF1355); High confidence in function and specificity. (462 aa)
	fadB3	Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (719 aa)
	SLJ85902.1	Short-chain dehydrogenase/reductase SDR, KR domain; High confidence in function and specificity. (221 aa)

Your Current Organism:

Psychrobacter sp. DABAL43B

NCBI taxonomy Id: 1028416
Other names: P. sp. DAB_AL43B, Psychrobacter sp. DAB_AL43B

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SLJ83231.1	SLJ83545.1	DABAL43B_0007	DABAL43B_0330	enoyl-CoA hydratase; High confidence in function and specificity.	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.611
SLJ83231.1	SLJ84335.1	DABAL43B_0007	DABAL43B_1138	enoyl-CoA hydratase; High confidence in function and specificity.	acetyl-CoA acetyltransferase / thiolase, N-terminal domain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.611
SLJ83231.1	SLJ84336.1	DABAL43B_0007	DABAL43B_1139	enoyl-CoA hydratase; High confidence in function and specificity.	3-hydroxyacyl-CoA dehydrogenase, NAD binding; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family.	0.942
SLJ83231.1	SLJ84968.1	DABAL43B_0007	DABAL43B_1773	enoyl-CoA hydratase; High confidence in function and specificity.	acetyl-CoA C-acetyltransferase; Thiolase, N-terminal domain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.605
SLJ83231.1	fadA1	DABAL43B_0007	DABAL43B_1518	enoyl-CoA hydratase; High confidence in function and specificity.	acetyl-CoA acetyltransferase, thiolase, alpha-lytic protease prodomain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.611
SLJ83231.1	fadB1	DABAL43B_0007	DABAL43B_1517	enoyl-CoA hydratase; High confidence in function and specificity.	3-hydroxyacyl-CoA dehydrogenase; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family.	0.942
SLJ83231.1	fadB3	DABAL43B_0007	DABAL43B_2537	enoyl-CoA hydratase; High confidence in function and specificity.	Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.953
SLJ83231.1	mvaB	DABAL43B_0007	DABAL43B_0402	enoyl-CoA hydratase; High confidence in function and specificity.	Hydroxymethylglutaryl-CoA lyase, mitochondrial; High confidence in function and specificity.	0.456
SLJ83545.1	SLJ83231.1	DABAL43B_0330	DABAL43B_0007	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	enoyl-CoA hydratase; High confidence in function and specificity.	0.611
SLJ83545.1	SLJ84335.1	DABAL43B_0330	DABAL43B_1138	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase / thiolase, N-terminal domain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.842
SLJ83545.1	SLJ84336.1	DABAL43B_0330	DABAL43B_1139	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase, NAD binding; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family.	0.999
SLJ83545.1	SLJ84968.1	DABAL43B_0330	DABAL43B_1773	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA C-acetyltransferase; Thiolase, N-terminal domain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.842
SLJ83545.1	atoA	DABAL43B_0330	DABAL43B_1883	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	3-oxoacid CoA-transferase, subunit B, Cytochrome C and Quinol oxidase polypeptide I; High confidence in function and specificity.	0.945
SLJ83545.1	atoD	DABAL43B_0330	DABAL43B_1884	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	3-oxoacid CoA-transferase subunit A; Coenzyme A transferase; High confidence in function and specificity.	0.982
SLJ83545.1	cat1	DABAL43B_0330	DABAL43B_1591	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA hydrolase/transferase N-terminal domain; High confidence in function and specificity.	0.920
SLJ83545.1	fadA1	DABAL43B_0330	DABAL43B_1518	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase, thiolase, alpha-lytic protease prodomain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	0.841
SLJ83545.1	fadB1	DABAL43B_0330	DABAL43B_1517	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family.	0.999
SLJ83545.1	fadB3	DABAL43B_0330	DABAL43B_2537	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.999
SLJ83545.1	mvaB	DABAL43B_0330	DABAL43B_0402	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA lyase, mitochondrial; High confidence in function and specificity.	0.921
SLJ83545.1	sdhA	DABAL43B_0330	DABAL43B_0120	acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.	Succinate dehydrogenase, flavoprotein subunit, FAD dependent oxidoreductase; High confidence in function and specificity; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.442