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| | SLJ83231.1 | enoyl-CoA hydratase; High confidence in function and specificity. (271 aa) |
| | patB | Aminotransferase, class I/classII; High confidence in function and specificity. (388 aa) |
| | glpD | Aerobic glycerol-3-phosphate dehydrogenase; High confidence in function and specificity. (551 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (276 aa) |
| | speC | Orn/DAP/Arg decarboxylase 2, N-terminal; High confidence in function and specificity; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (393 aa) |
| | ppnP | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (111 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (269 aa) |
| | SLJ83325.1 | Fructose-bisphosphate aldolase, class-I; High confidence in function and specificity. (296 aa) |
| | argH | Argininosuccinate lyase, 3-carboxy-cis,cis-muconate cycloisomerase; High confidence in function and specificity. (494 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (351 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (370 aa) |
| | gltA | Citrate synthase, type II; High confidence in function and specificity; Belongs to the citrate synthase family. (426 aa) |
| | sdhC | Succinate dehydrogenase, cytochrome b560 subunit; High confidence in function and specificity. (128 aa) |
| | sdhD | Succinate dehydrogenase, hydrophobic membrane anchor; High confidence in function and specificity. (135 aa) |
| | sdhA | Succinate dehydrogenase, flavoprotein subunit, FAD dependent oxidoreductase; High confidence in function and specificity; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (616 aa) |
| | sdhB1 | Succinate dehydrogenase/fumarate reductase iron-sulphur protein; High confidence in function and specificity; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa) |
| | sucA | 2-oxoglutarate dehydrogenase, Dehydrogenase E1 component; High confidence in function and specificity. (961 aa) |
| | sucB | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (412 aa) |
| | lpd | Alanine dehydrogenase/PNT, C-terminal domain, nitrite reductase [NAD(P)H], large subunit; High confidence in function and specificity. (483 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucD | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa) |
| | galU | UTP-glucose-1-phosphate uridylyltransferase; Uridine diphosphoglucose pyrophosphorylase, Nucleotidyl transferase; High confidence in function and specificity. (294 aa) |
| | pgi | Phosphoglucose isomerase; High confidence in function and specificity; Belongs to the GPI family. (560 aa) |
| | manB | Phosphomannomutase; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; High confidence in function and specificity. (510 aa) |
| | panB | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (266 aa) |
| | panC | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (294 aa) |
| | ubiG | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (281 aa) |
| | plsB | plsB: glycerol-3-phosphate O-acyltransferase; High confidence in function and specificity; Belongs to the GPAT/DAPAT family. (938 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa) |
| | purC | SAICAR synthetase, phosphoribosylaminoimidazole-succinocarboxamide synthase; High confidence in function and specificity. (237 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase, Aminotransferase class-III; High confidence in function and specificity. (433 aa) |
| | accA | acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (267 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (277 aa) |
| | panD | Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | ipk | 4-diphosphocytidyl-2-C-methyl-D- erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (322 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (471 aa) |
| | trpB1 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (408 aa) |
| | acsA | acetyl-CoA synthetase/ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1338 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (450 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (295 aa) |
| | hemF | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (336 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (230 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (682 aa) |
| | suhB | Inositol monophosphatase family; High confidence in function and specificity. (275 aa) |
| | pldA | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (485 aa) |
| | SLJ83545.1 | acetyl-CoA C-acetyltransferase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | hom | Homoserine dehydrogenase; High confidence in function and specificity. (447 aa) |
| | SLJ83551.1 | Phosphoglycolate phosphatase; High confidence in function and specificity. (236 aa) |
| | purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (444 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (186 aa) |
| | icd | Isocitrate dehydrogenase NADP-dependent, prokaryotic, Glutaminyl-tRNA synthetase; High confidence in function and specificity. (419 aa) |
| | icd2 | Isocitrate dehydrogenase NADP-dependent, monomeric type, Monomeric isocitrate dehydrogenase; High confidence in function and specificity; Belongs to the monomeric-type IDH family. (739 aa) |
| | ubiC | Chorismate pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (168 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (433 aa) |
| | mvaB | Hydroxymethylglutaryl-CoA lyase, mitochondrial; High confidence in function and specificity. (306 aa) |
| | serA | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; High confidence in function and specificity. (408 aa) |
| | metX | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (475 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (339 aa) |
| | metH | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1303 aa) |
| | trpF | N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity; Belongs to the TrpF family. (227 aa) |
| | trpB3 | Tryptophan synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (424 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (274 aa) |
| | accD | acetylCoA carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (328 aa) |
| | fabD | [acyl-carrier-protein] S-malonyltransferase; Malonyl CoA-acyl carrier protein transacylase, Polyketide synthase, acyl transferase domain; High confidence in function and specificity. (322 aa) |
| | fabG1 | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (242 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | ilvI | Acetolactate synthase isozyme 3 large subunit, biosynthetic, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; High confidence in function and specificity. (608 aa) |
| | ilvH | Acetolactate synthase isozyme 3 small subunit, ACT domain; High confidence in function and specificity. (165 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | fbp | Fructose-1,6-bisphosphatase class 1/Sedoheputulose-1,7-bisphosphatase, Inositol monophosphatase family; High confidence in function and specificity; Belongs to the FBPase class 1 family. (327 aa) |
| | wrbA | Flavodoxin/nitric oxide synthase; Flavoprotein WrbA, Bacterial extracellular solute-binding proteins, family 5 Middle; High confidence in function and specificity; Belongs to the WrbA family. (204 aa) |
| | pssA | Phosphatidylserine synthase; CDP-diacylglycerol-serine O-phosphatidyltransferase; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (310 aa) |
| | katE | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (695 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (303 aa) |
| | algC | Phosphomannomutase; Phosphoglucomutase, alpha/beta/alpha domain I; High confidence in function and specificity. (628 aa) |
| | ubiH | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; 2-octaprenyl-6-methoxyphenol hydroxylase, Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, Thi4 family; High confidence in function and specificity. (444 aa) |
| | ubiF | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, TrkA-N domain; High confidence in function and specificity. (434 aa) |
| | ynbB | Phosphatidate cytidylyltransferase; Specificity unclear. (294 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (435 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (371 aa) |
| | surE | Nucleoside 5'-monophosphate phosphohydrolase, survival protein SurE-like phosphatase/nucleotidase; High confidence in function and specificity. (241 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (552 aa) |
| | pgk | Phosphoglycerate kinase; High confidence in function and specificity; Belongs to the phosphoglycerate kinase family. (404 aa) |
| | fda | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (345 aa) |
| | ubiE | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (375 aa) |
| | SLJ83998.1 | Aminotransferase, class I/classII, beta-eliminating lyase; High confidence in function and specificity. (546 aa) |
| | acnB | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Aconitate hydratase 2, citrate hydro-lyase 2; High confidence in function and specificity; Belongs to the aconitase/IPM isomerase family. (867 aa) |
| | SLJ84128.1 | Dihydrolipoyl dehydrogenase 3; High confidence in function and specificity. (500 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (966 aa) |
| | gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa) |
| | gcvT | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (395 aa) |
| | gcdH | Glutaryl-CoA dehydrogenase, mitochondrial; High confidence in function and specificity. (400 aa) |
| | ppnP-2 | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (94 aa) |
| | SLJ84198.1 | Acetyl-coenzyme A synthetase, AMP-dependent; High confidence in function and specificity. (564 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (388 aa) |
| | sgaA | Serine-glyoxylate aminotransferase, class V; High confidence in function and specificity. (391 aa) |
| | SLJ84335.1 | acetyl-CoA acetyltransferase / thiolase, N-terminal domain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | SLJ84336.1 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa) |
| | fadE1 | Long-chain specific acyl-CoA dehydrogenase, mitochondrial, type 1, middle domain; High confidence in function and specificity. (383 aa) |
| | sdhB3 | Succinate dehydrogenase iron-sulfur subunit; High confidence in function and specificity; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa) |
| | argD1 | Acetylornithine aminotransferase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (400 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa) |
| | pchA | Aldehyde dehydrogenase; High confidence in function and specificity; Belongs to the aldehyde dehydrogenase family. (494 aa) |
| | aroF | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (360 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (410 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (182 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (517 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (219 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (307 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family. (295 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (378 aa) |
| | trpG1 | Anthranilate synthase component II; High confidence in function and specificity. (207 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (373 aa) |
| | SLJ84584.1 | Alcohol dehydrogenase, iron-type; High confidence in function and specificity. (436 aa) |
| | fabI | Enoyl-[acyl-carrier-protein] reductase (NADH); Enoyl-[acyl-carrier protein] reductase I, NADH-dependent; High confidence in function and specificity. (268 aa) |
| | argD3 | Acetylornithine aminotransferase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (393 aa) |
| | purD | Phosphoribosylamine-glycine ligase; High confidence in function and specificity; Belongs to the GARS family. (450 aa) |
| | cysG | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (574 aa) |
| | sat | Sulfate adenylyltransferase, ATP-sulfurylase; High confidence in function and specificity; Belongs to the sulfate adenylyltransferase family. (417 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase; High confidence in function and specificity. (187 aa) |
| | SLJ84703.1 | Long-chain specific acyl-CoA dehydrogenase, mitochondrial; High confidence in function and specificity. (175 aa) |
| | fadE3 | Long-chain specific acyl-CoA dehydrogenase, mitochondrial; High confidence in function and specificity. (191 aa) |
| | fadB1 | 3-hydroxyacyl-CoA dehydrogenase; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family. (731 aa) |
| | fadA1 | acetyl-CoA acetyltransferase, thiolase, alpha-lytic protease prodomain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | fadE5 | Long-chain specific acyl-CoA dehydrogenase, type 1; High confidence in function and specificity. (383 aa) |
| | dgk | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (147 aa) |
| | SLJ84733.1 | Amine oxidase; High confidence in function and specificity. (533 aa) |
| | rhbE | L-lysine 6-monooxygenase (NADPH); Lysine/ornithine N-monooxygenase, rhizobactin siderophore biosynthesis protein rhbE; High confidence in function and specificity. (447 aa) |
| | SLJ84750.1 | Alcohol dehydrogenase, iron-type; High confidence in function and specificity. (439 aa) |
| | cat1 | Acetyl-CoA hydrolase/transferase N-terminal domain; High confidence in function and specificity. (516 aa) |
| | cysE | Serine acetyltransferase, N-terminal; High confidence in function and specificity. (312 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (787 aa) |
| | hisC1 | Histidinol-phosphate aminotransferase, Aminotransferase class I and II; High confidence in function and specificity; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (380 aa) |
| | pheA | [5.4.99.5, 4.2.1.51], Bifunctional P-protein, chorismate mutase/prephenate dehydratase, Osmosensory transporter coiled coil; High confidence in function and specificity. (393 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (313 aa) |
| | sdaA | Iron-sulphur-dependent L-serine dehydratase single chain form, Serine dehydratase beta chain; High confidence in function and specificity; Belongs to the iron-sulfur dependent L-serine dehydratase family. (477 aa) |
| | argJ | Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (407 aa) |
| | SLJ84833.1 | Acyl-CoA oxidase/dehydrogenase, type 1, Acyl-CoA dehydrogenase, N-terminal domain; High confidence in function and specificity. (422 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (290 aa) |
| | rfbB | dTDP-glucose 4,6-dehydratase, Dihydrodipicolinate reductase, N-terminus; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (352 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa) |
| | accB3 | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (142 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (453 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (597 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (163 aa) |
| | purB | Adenylosuccinate lyase; High confidence in function and specificity; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (463 aa) |
| | putA | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1085 aa) |
| | SLJ84905.1 | Amine oxidase, Glucose inhibited division protein A; High confidence in function and specificity. (533 aa) |
| | SLJ84907.1 | Trp repressor binding protein; Flavodoxin/nitric oxide synthase; Hypothetical protein. (209 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (511 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase, NAD-dependent, Pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (436 aa) |
| | ilvD1 | Dihydroxy-acid/6-phosphogluconate dehydratase; High confidence in function and specificity; Belongs to the IlvD/Edd family. (636 aa) |
| | fabG3 | 3-ketoacyl-(acyl-carrier-protein) reductase; Polyketide synthase/Fatty acid synthase, KR; High confidence in function and specificity. (466 aa) |
| | SLJ84968.1 | acetyl-CoA C-acetyltransferase; Thiolase, N-terminal domain; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. (548 aa) |
| | aceF | Acetyltransferase component of pyruvate dehydrogenase complex;, 2-oxoacid dehydrogenase acyltransferase, catalytic domain, HlyD family secretion protein; High confidence in function and specificity. (577 aa) |
| | aceE | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (940 aa) |
| | ppsA | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (794 aa) |
| | glxK | Glycerate kinase, Protein of unknown function (DUF2523); High confidence in function and specificity; Belongs to the glycerate kinase type-1 family. (378 aa) |
| | tyrB | Aspartate/other aminotransferase, Aminotransferase class I and II; High confidence in function and specificity. (398 aa) |
| | ansA | L-asparaginase; Asparaginase/glutaminase, Heat-labile enterotoxin beta chain; High confidence in function and specificity. (366 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (367 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa) |
| | leuC | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa) |
| | SLJ85088.1 | Gluconate 2-dehydrogenase (acceptor); Membrane-bound alcohol dehydrogenase, cytochrome c subunit, Cytochrome C1 family; High confidence in function and specificity. (458 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (367 aa) |
| | lysC | Aspartate kinase, monofunctional class, Amino acid kinase family; High confidence in function and specificity; Belongs to the aspartokinase family. (428 aa) |
| | purH | Bifunctionalphosphoribosylaminoimidazolecarboxa m ide formyltransferase/IMP cyclohydrolase; 3.5.4.10], AICARFT/IMPCHase bienzyme, MGS-like domain; High confidence in function and specificity. (526 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (355 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (378 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (390 aa) |
| | gapA | Glyceraldehyde/Erythrose phosphate dehydrogenase family, Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (481 aa) |
| | coq7 | Ubiquinone biosynthesis monooxygenase Coq7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (214 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (377 aa) |
| | dxr | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (402 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; High confidence in function and specificity; Belongs to the CDS family. (269 aa) |
| | uppS | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (252 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | ispB | Octaprenyl-diphosphate synthase; Polyprenyl synthetase-related, Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. (349 aa) |
| | hemB | Tetrapyrrole biosynthesis, porphobilinogen synthase; High confidence in function and specificity; Belongs to the ALAD family. (335 aa) |
| | SLJ85268.1 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (331 aa) |
| | epd | Glyceraldehyde/Erythrose phosphate dehydrogenase family, Dihydrodipicolinate reductase, N-terminus; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (391 aa) |
| | dhaS | Aldehyde dehydrogenase domain; High confidence in function and specificity; Belongs to the aldehyde dehydrogenase family. (508 aa) |
| | adh | Alcohol dehydrogenase superfamily, zinc-containing, ThiF family; High confidence in function and specificity. (342 aa) |
| | tkt | Transketolase, bacterial-like, Dehydrogenase E1 component; High confidence in function and specificity; Belongs to the transketolase family. (665 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; Phosphoribosylformylglycinamidine cyclo-ligase, RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); High confidence in function and specificity. (349 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (233 aa) |
| | aceA | Isocitrate lyase family; High confidence in function and specificity. (529 aa) |
| | argG | Argininosuccinate synthase, type 1 subfamily, ExsB; High confidence in function and specificity; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (412 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (274 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (438 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (734 aa) |
| | glcD3 | FAD-linked oxidase, C-terminal; High confidence in function and specificity. (492 aa) |
| | glcE | Glycolate oxidase FAD binding subunit; FAD-binding, type 2; High confidence in function and specificity. (352 aa) |
| | glcF | Glycolate oxidase, iron-sulphur subunit, Cysteine-rich domain; High confidence in function and specificity. (402 aa) |
| | fumC | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa) |
| | trpE | Anthranilate synthase component I; Chorismate binding, C-terminal; High confidence in function and specificity. (472 aa) |
| | trpG3 | Anthranilate synthase component II; Glutamine amidotransferase type 1; High confidence in function and specificity. (215 aa) |
| | adhC | 1.1.1.1], Alcohol dehydrogenase superfamily, zinc-containing; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (376 aa) |
| | ubiA | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (307 aa) |
| | rpe | Ribulose-phosphate 3-epimerase, Thiamine monophosphate synthase/TENI; High confidence in function and specificity; Belongs to the ribulose-phosphate 3-epimerase family. (240 aa) |
| | katA | Catalase, N-terminal, Catalase-related immune-responsive; High confidence in function and specificity. (510 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (323 aa) |
| | ribF | Riboflavin kinase / FMN adenylyltransferase; 2.7.7.2], Riboflavin kinase, bacterial, FAD synthetase; High confidence in function and specificity; Belongs to the ribF family. (347 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa) |
| | argE | Acetylornithine deacetylase, Peptidase family M20/M25/M40; High confidence in function and specificity. (412 aa) |
| | serB | Phosphoserine phosphatase SerB, putative Phosphatase; High confidence in function and specificity. (395 aa) |
| | SLJ85640.1 | Putative membrane protein; Uncharacterised protein family UPF0093; Specificity unclear. (144 aa) |
| | SLJ85651.1 | Short-chain dehydrogenase/reductase SDR, KR domain; High confidence in function and specificity. (265 aa) |
| | gltD | 1.4.1.14], Glutamate synthase, NADH/NADPH, small subunit 2, Malic enzyme, NAD binding domain; High confidence in function and specificity. (473 aa) |
| | gltB3 | Glutamate synthase subunit alpha; 1.4.1.14], Glutamine amidotransferase, type II; High confidence in function and specificity. (1487 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (377 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (186 aa) |
| | hisC3 | Histidinol-phosphate aminotransferase, Aminotransferase class I and II; High confidence in function and specificity; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (377 aa) |
| | hisD3 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (431 aa) |
| | hisG | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (231 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (277 aa) |
| | fadA3 | 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (390 aa) |
| | fadB3 | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (719 aa) |
| | idsA | Geranylgeranyl diphosphate synthase; 2.5.1.10 2.5.1.29], olyprenyl synthetase-related, heptaprenyl diphosphate synthase component II; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. (368 aa) |
| | dgkA | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (165 aa) |
| | SLJ85754.1 | 5'-nucleotidase; 5-nucleotidase; High confidence in function and specificity. (350 aa) |
| | SLJ85781.1 | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, Trehalose-phosphatase; High confidence in function and specificity. (311 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; 3.5.4.19], Phosphoribosyl-ATP pyrophosphohydrolase; High confidence in function and specificity; In the N-terminal section; belongs to the PRA-CH family. (288 aa) |
| | SLJ85849.1 | Sterol 4-alpha-methyl-oxidase; Fatty acid hydroxylase; Specificity unclear. (286 aa) |
| | gltX3 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (515 aa) |
| | acnA3 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (935 aa) |
| | thrB | Homoserine kinase ThrB; High confidence in function and specificity; Belongs to the pseudomonas-type ThrB family. (416 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (260 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (173 aa) |
| | metE3 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Methionine synthase, catalytic subunit-predicted, cobalamin-independent, Uroporphyrinogen decarboxylase (URO-D); High confidence in function and specificity. (351 aa) |
| | argA | N-acetylglutamate synthase; Amino-acid N-acetyltransferase, Acetyltransferase (GNAT) family; High confidence in function and specificity; Belongs to the acetyltransferase family. ArgA subfamily. (440 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, PcrB family; High confidence in function and specificity. (247 aa) |
| | avtA | Valine-pyruvate transaminase; Aminotransferase, class I/classII; High confidence in function and specificity. (443 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (214 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; High confidence in function and specificity. (217 aa) |
| | gph | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (225 aa) |
| | ilvD3 | Dihydroxy-acid/6-phosphogluconate dehydratase, Protein of unknown function (DUF3650); High confidence in function and specificity; Belongs to the IlvD/Edd family. (560 aa) |
| | hemN3 | Coproporphyrinogen III oxidase, oxygen-independent, HemN, HemN C-terminal region; High confidence in function and specificity. (514 aa) |
| | thrC | Threonine synthase, Pyridoxal-phosphate dependent enzyme; High confidence in function and specificity. (473 aa) |
| | ribE | Riboflavin synthase subunit alpha; Lumazine binding domain; High confidence in function and specificity. (224 aa) |
| | ribD | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (351 aa) |
