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| | fadE | acyl-CoA dehydrogenase. (815 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (878 aa) |
| | acsA2 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa) |
| | PSCI_0318 | Aminotransferase AlaT. (403 aa) |
| | fumC-2 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa) |
| | PSCI_0446 | Acetolactate synthase; Belongs to the TPP enzyme family. (533 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (558 aa) |
| | PSCI_0548 | Carboxyphosphonoenolpyruvate phosphonomutase. (289 aa) |
| | PSCI_0641 | Branched-chain amino acid aminotransferase. (339 aa) |
| | PSCI_0756 | Branched-chain alpha-keto acid dehydrogenase subunit E2. (367 aa) |
| | PSCI_0757 | Pyruvate dehydrogenase E1 component subunit beta. (328 aa) |
| | pdhA | Pyruvate dehydrogenase complex, E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (365 aa) |
| | PSCI_0780 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (696 aa) |
| | PSCI_0787 | long-chain-fatty-acid-CoA ligase. (560 aa) |
| | mqo | Malate:quinone oxidoreductase. (503 aa) |
| | PSCI_0905 | Acetolactate synthase; Belongs to the TPP enzyme family. (552 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | ilvH | Acetolactate synthase 3 regulatory subunit. (163 aa) |
| | PSCI_0961 | Acetolactate synthase 3 catalytic subunit. (566 aa) |
| | acs_2 | acetate-CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa) |
| | PSCI_1069 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (295 aa) |
| | PSCI_1095 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa) |
| | PSCI_1218 | Putative lipoate-protein ligase A. (235 aa) |
| | PSCI_1259 | hydroxymethylglutaryl-CoA lyase. (301 aa) |
| | PSCI_1260 | Biotin carboxylase. (634 aa) |
| | PSCI_1261 | gamma-carboxygeranoyl-CoA hydratase. (262 aa) |
| | PSCI_1262 | propionyl-CoA carboxylase. (540 aa) |
| | PSCI_1263 | isovaleryl-CoA dehydrogenase. (391 aa) |
| | PSCI_1266 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | PSCI_1282 | acyl-CoA dehydrogenase domain-containing protein. (591 aa) |
| | PSCI_1284 | acyl-CoA dehydrogenase. (601 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (724 aa) |
| | PSCI_1372 | L(+)-tartrate dehydratase subunit beta. (207 aa) |
| | PSCI_1373 | Tartrate dehydratase subunit alpha. (299 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (514 aa) |
| | mqo-2 | Malate:quinone oxidoreductase. (547 aa) |
| | PSCI_1560 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa) |
| | PSCI_1832 | Pyruvate carboxylase subunit A. (477 aa) |
| | PSCI_1833 | Pyruvate carboxylase subunit B. (602 aa) |
| | PSCI_1875 | Coenzyme A transferase PsecoA. (497 aa) |
| | gcdH | glutaryl-CoA dehydrogenase. (413 aa) |
| | PSCI_1949 | D-isomer specific 2-hydroxyacid dehydrogenase. (332 aa) |
| | gabD | Succinate-semialdehyde dehydrogenase I; Belongs to the aldehyde dehydrogenase family. (480 aa) |
| | gabT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | PSCI_2053 | FAD linked oxidase domain-containing protein. (463 aa) |
| | PSCI_2055 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (579 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (613 aa) |
| | PSCI_2228 | NADP-dependent malic enzyme. (422 aa) |
| | PSCI_2274 | Biotin carboxylase/biotin carboxyl carrier protein. (578 aa) |
| | aceF | Dihydrolipoamide acetyltransferase, E2 component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa) |
| | aceE | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa) |
| | PSCI_2428 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | PSCI_2429 | acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa) |
| | PSCI_2434 | Beta alanine-pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa) |
| | PSCI_2602 | acyl-CoA dehydrogenase domain-containing protein. (549 aa) |
| | fumC | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa) |
| | PSCI_2927 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa) |
| | PSCI_3093 | MaoC-like domain-containing protein. (156 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa) |
| | maeA | Malate dehydrogenase. (563 aa) |
| | aceK | Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (571 aa) |
| | PSCI_3340 | Tartrate dehydrogenase. (350 aa) |
| | PSCI_3356 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa) |
| | PSCI_3358 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa) |
| | PSCI_3391 | Putative uncharacterized protein. (194 aa) |
| | PSCI_3557 | Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa) |
| | PSCI_3559 | 3-hydroxyacyl-CoA dehydrogenase. (506 aa) |
| | PSCI_3560 | enoyl-CoA hydratase. (263 aa) |
| | PSCI_3561 | enoyl-CoA hydratase-isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (269 aa) |
| | PSCI_3579 | Malate synthase G. (548 aa) |
| | PSCI_3611 | acyl-CoA dehydrogenase. (383 aa) |
| | PSCI_3612 | enoly-CoA hydratase/isomerase family protein. (385 aa) |
| | acnA | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (914 aa) |
| | PSCI_3716 | enoyl-CoA hydratase. (229 aa) |
| | leuC | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (213 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa) |
| | PSCI_3822 | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (551 aa) |
| | PSCI_3823 | Electron transfer flavoprotein subunit beta. (249 aa) |
| | etfA-2 | Electron transfer flavoprotein subunit alpha. (309 aa) |
| | gltA | Type II citrate synthase; Belongs to the citrate synthase family. (429 aa) |
| | PSCI_3833 | Succinate dehydrogenase, cytochrome b556 subunit. (85 aa) |
| | PSCI_3834 | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa) |
| | sdhA | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (570 aa) |
| | sdhB | Succinate dehydrogenase iron-sulfur subunit. (234 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component. (938 aa) |
| | PSCI_3838 | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (413 aa) |
| | PSCI_3839 | Dihydrolipoamide dehydrogenase. (478 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucD | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | PSCI_3974 | NAD-dependent aldehyde dehydrogenase. (476 aa) |
| | PSCI_4152 | Zinc-containing alcohol dehydrogenase superfamily protein. (331 aa) |
| | PSCI_4232 | Pyruvate dehydrogenase; Belongs to the TPP enzyme family. (572 aa) |
| | PSCI_4285 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa) |
| | PSCI_4286 | 2-ketocyclohexanecarboxyl-CoA hydrolase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | PSCI_4318 | enoyl-CoA hydratase. (270 aa) |
| | PSCI_4460 | acyl-CoA dehydrogenase. (388 aa) |
| | PSCI_4507 | Methylmalonate-semialdehyde dehydrogenase. (499 aa) |
| | lldD | Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. (378 aa) |
| | PSCI_4565 | Lactaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa) |
| | PSCI_4610 | 3-hydroxyisobutyrate dehydrogenase family protein. (296 aa) |
| | PSCI_4611 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (505 aa) |
| | PSCI_4834 | Methylcitrate synthase; Belongs to the citrate synthase family. (375 aa) |
| | prpB | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (297 aa) |
| | PSCI_4907 | Tartrate dehydrogenase. (356 aa) |
| | mqo-3 | Malate:quinone oxidoreductase. (548 aa) |
| | PSCI_4976 | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa) |
| | accC2 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa) |
| | PSCI_4978 | Biotin/lipoyl attachment domain-containing protein. (141 aa) |
| | PSCI_5021 | Aldehyde dehydrogenase family protein. (463 aa) |
| | icd | Isocitrate dehydrogenase, NADP-dependent. (420 aa) |
| | icd-2 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (741 aa) |
| | PSCI_5422 | Isocitrate lyase. (441 aa) |
| | PSCI_5466 | 3-oxoacid CoA-transferase subunit A family protein. (232 aa) |
| | PSCI_5467 | 3-oxoacid CoA-transferase. (218 aa) |
| | fadA | 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (391 aa) |
| | fadB | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (721 aa) |
| | PSCI_5519 | Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (869 aa) |
| | PSCI_5564 | o-succinylbenzoate-CoA ligase. (497 aa) |
| | PSCI_5565 | NADPH:quinone reductase. (340 aa) |
| | PSCI_5566 | enoyl-CoA hydratase/isomerase. (233 aa) |
| | accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (308 aa) |
