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| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (878 aa) |
| | PSCI_0033 | Lipoprotein. (356 aa) |
| | thrC | Threonine synthase. (469 aa) |
| | menG2 | Dimethylmenaquinone methyltransferase. (224 aa) |
| | PSCI_0143 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | phhB | Pterin-4-alpha-carbinolamine dehydratase. (118 aa) |
| | PSCI_0346 | Chorismate mutase/prephenate dehydratase. (364 aa) |
| | fumC-2 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa) |
| | PSCI_0379 | Threonine-phosphate decarboxylase. (335 aa) |
| | cobD | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (302 aa) |
| | cysM | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa) |
| | PSCI_0429 | Xylose isomerase domain protein TIM barrel. (312 aa) |
| | PSCI_0436 | AP endonuclease. (298 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa) |
| | PSCI_0499 | ybaK/ebsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (156 aa) |
| | PSCI_0548 | Carboxyphosphonoenolpyruvate phosphonomutase. (289 aa) |
| | PSCI_0622 | Putative uncharacterized protein. (313 aa) |
| | PSCI_0669 | Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase. (224 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa) |
| | moaC_2 | Molybdenum cofactor biosynthesis protein C. (148 aa) |
| | algL | poly(beta-D-mannuronate) lyase; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism; Belongs to the polysaccharide lyase 5 family. (374 aa) |
| | folX | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. (123 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (341 aa) |
| | PSCI_0816 | Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (479 aa) |
| | PSCI_0948 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (212 aa) |
| | PSCI_0968 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (254 aa) |
| | PSCI_1053 | ferredoxin-NADP reductase. (292 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (363 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (280 aa) |
| | PSCI_1221 | Anthranilate synthase component II. (199 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (490 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (117 aa) |
| | PSCI_1259 | hydroxymethylglutaryl-CoA lyase. (301 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (197 aa) |
| | PSCI_1372 | L(+)-tartrate dehydratase subunit beta. (207 aa) |
| | PSCI_1373 | Tartrate dehydratase subunit alpha. (299 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (514 aa) |
| | PSCI_1456 | Cation transport protein chaC; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (221 aa) |
| | ubiD | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (488 aa) |
| | PSCI_1464 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (336 aa) |
| | PSCI_1466 | Isoprenoid biosynthesis protein with amidotransferase-like domain; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. (224 aa) |
| | PSCI_1488 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (259 aa) |
| | argH | Argininosuccinate lyase. (464 aa) |
| | cyaA | Adenylate cyclase. (946 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (415 aa) |
| | PSCI_1505 | Putative secondary thiamine-phosphate synthase enzyme. (150 aa) |
| | PSCI_1510 | Pectate lyase. (379 aa) |
| | paaG | P-hydroxycinnamoyl CoA hydratase/lyase; Belongs to the enoyl-CoA hydratase/isomerase family. (276 aa) |
| | PSCI_1589 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa) |
| | PSCI_1661 | Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (240 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (409 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa) |
| | PSCI_1781 | Dimethylmenaquinone methyltransferase. (213 aa) |
| | PSCI_1793 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (309 aa) |
| | PSCI_1800 | Glucarate dehydratase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (424 aa) |
| | PSCI_1833 | Pyruvate carboxylase subunit B. (602 aa) |
| | aspA | Aspartate ammonia-lyase. (474 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa) |
| | ubiC | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (184 aa) |
| | PSCI_1940 | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (360 aa) |
| | ilvA | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa) |
| | PSCI_2055 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (579 aa) |
| | xylK | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (339 aa) |
| | ltaE | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (347 aa) |
| | eutC | Ethanolamine ammonia-lyase small subunit; Belongs to the EutC family. (273 aa) |
| | PSCI_2097 | Ethanolamine ammonia lyase large subunit. (464 aa) |
| | PSCI_2109 | Class II aldolase/adducin family protein. (212 aa) |
| | PSCI_2135 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (346 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (613 aa) |
| | mutM | Formamidopyrimidine/5-formyluracil/5- hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (270 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (367 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa) |
| | PSCI_2247 | Thioester dehydrase family protein. (152 aa) |
| | PSCI_2256 | Phenylalanine ammonia-lyase/histidase family protein. (515 aa) |
| | PSCI_2259 | AMP-dependent synthetase and ligase. (569 aa) |
| | PSCI_2272 | Putative uncharacterized protein; Belongs to the D-glutamate cyclase family. (264 aa) |
| | PSCI_2300 | L-serine dehydratase, iron-sulfur-dependent, single chain form. (458 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (630 aa) |
| | psd | Thiosulfate sulfurtransferase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (287 aa) |
| | nnrD | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (498 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa) |
| | PSCI_2440 | Dihydrodipicolinate synthetase family protein; Belongs to the DapA family. (293 aa) |
| | speA | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa) |
| | PSCI_2466 | Class II aldolase/adducin family protein. (246 aa) |
| | PSCI_2496 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (300 aa) |
| | ubiX | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (209 aa) |
| | PSCI_2534 | Mandelate racemase/muconate lactonizing protein. (363 aa) |
| | PSCI_2553 | Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (387 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (335 aa) |
| | PSCI_2636 | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. (325 aa) |
| | garD | D-galactarate dehydratase. (517 aa) |
| | PSCI_2686 | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. (365 aa) |
| | rlpA-2 | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (122 aa) |
| | fumC | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa) |
| | PSCI_2927 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa) |
| | PSCI_2997 | Diaminopropionate ammonia-lyase. (410 aa) |
| | PSCI_2999 | Diaminopropionate ammonia-lyase. (410 aa) |
| | mltF | Membrane-bound lytic transglycosylase F; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (465 aa) |
| | PSCI_3052 | S-(hydroxymethyl)glutathione synthase. (132 aa) |
| | PSCI_3093 | MaoC-like domain-containing protein. (156 aa) |
| | PSCI_3120 | MmgE/PrpD family protein. (466 aa) |
| | PSCI_3142 | ThiF family protein. (273 aa) |
| | fabZ | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa) |
| | queE | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | maeA | Malate dehydrogenase. (563 aa) |
| | PSCI_3312 | Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa) |
| | PSCI_3331 | Mandelate racemase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (391 aa) |
| | hpaI | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. (266 aa) |
| | hpaH | 2-oxo-hepta-3-ene-1,7-dioic acid hydratase. (267 aa) |
| | PSCI_3411 | 4-hydroxyphenylacetate degradation isomerase, C-terminal subunit. (259 aa) |
| | PSCI_3412 | 4-hydroxyphenylacetate degradation bigunctional isomerase. (223 aa) |
| | PSCI_3529 | Dyp-type peroxidase family protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (435 aa) |
| | dsdA | D-serine dehydratase; Belongs to the serine/threonine dehydratase family. DsdA subfamily. (449 aa) |
| | acnA | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (914 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (244 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (363 aa) |
| | leuC | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (213 aa) |
| | eda | 2-dehydro-3-deoxy-6-phosphogalactonate aldolase. (208 aa) |
| | PSCI_3866 | Putative uncharacterized protein. (768 aa) |
| | PSCI_3867 | Putative uncharacterized protein. (773 aa) |
| | PSCI_3868 | Putative uncharacterized protein. (946 aa) |
| | PSCI_3902 | 3-carboxy-cis,cis-muconate cycloisomerase. (458 aa) |
| | PSCI_3911 | 4-hydroxyphenylpyruvate dioxygenase. (635 aa) |
| | PSCI_4106 | Transposon. (156 aa) |
| | PSCI_4114 | Lipoprotein. (116 aa) |
| | PSCI_4187 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (297 aa) |
| | PSCI_4209 | Putative transcriptional regulator. (202 aa) |
| | PSCI_4228 | Intracellular protease/amidase. (225 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (326 aa) |
| | PSCI_4391 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (173 aa) |
| | dlpA2 | Protein DlpA. (220 aa) |
| | menG4 | Dimethylmenaquinone methyltransferase MenG. (221 aa) |
| | PSCI_4458 | Sulfopyruvate decarboxylase alpha subunit. (176 aa) |
| | PSCI_4459 | Sulfopyruvate decarboxylase. (198 aa) |
| | PSCI_4464 | Putative uncharacterized protein. (280 aa) |
| | PSCI_4465 | HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (271 aa) |
| | dsdA-2 | D-serine dehydratase; Belongs to the serine/threonine dehydratase family. DsdA subfamily. (443 aa) |
| | PSCI_4528 | Deoxyribodipyrimidine photolyase-like protein protein. (518 aa) |
| | PSCI_4540 | Ornithine cyclodeaminase. (422 aa) |
| | dapA-2 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | rhmD | Mandelate racemase/muconate lactonizing protein; Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy- L-rhamnonate (KDR). (394 aa) |
| | PSCI_4564 | 2-dehydro-3-deoxyglucarate aldolase; Belongs to the HpcH/HpaI aldolase family. (266 aa) |
| | PSCI_4753 | Mandelate racemase/muconate lactonizing protein. (389 aa) |
| | PSCI_4770 | Urea amidolyase-like protein. (1209 aa) |
| | dapA-3 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | PSCI_4827 | Ribonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (162 aa) |
| | PSCI_4833 | Aconitate hydratase. (861 aa) |
| | prpB | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (297 aa) |
| | PSCI_4862 | Transglycosylase, SLT family protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (475 aa) |
| | ribB-2 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (384 aa) |
| | fabA | 3-hydroxydecanoyl-(acyl carrier protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa) |
| | hutH | Histidine ammonia-lyase. (510 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (560 aa) |
| | PSCI_5093 | GntR family transcriptional regulator. (451 aa) |
| | PSCI_5121 | Dimethylmenaquinone methyltransferase. (224 aa) |
| | PSCI_5169 | PEP phosphonomutase-like enzyme. (274 aa) |
| | PSCI_5216 | Glucarate dehydratase. (447 aa) |
| | gmd | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (348 aa) |
| | PSCI_5309 | S-(hydroxymethyl)glutathione synthase. (118 aa) |
| | PSCI_5325 | MltA domain-containing protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (385 aa) |
| | cysG | uroporphyrinogen-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (464 aa) |
| | PSCI_5418 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (477 aa) |
| | PSCI_5422 | Isocitrate lyase. (441 aa) |
| | PSCI_5442 | 6-pyruvoyl tetrahydrobiopterin synthase. (137 aa) |
| | fadB | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (721 aa) |
| | PSCI_5519 | Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (869 aa) |
| | ilvA1 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (511 aa) |
| | PSCI_5566 | enoyl-CoA hydratase/isomerase. (233 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (403 aa) |
| | mltG | YceG-like family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (372 aa) |
| | PSCI_5590 | 4-amino-4-deoxychorismate lyase. (271 aa) |
