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KC8_07095 KC8_07095 KC8_07090 KC8_07090 KC8_10380 KC8_10380 leuA leuA KC8_15430 KC8_15430 KC8_08650 KC8_08650 KC8_08660 KC8_08660 pdhA pdhA mdh mdh KC8_18010 KC8_18010 KC8_18205 KC8_18205 KC8_15150 KC8_15150 KC8_15170 KC8_15170 KC8_01910 KC8_01910 KC8_11050 KC8_11050 KC8_19610 KC8_19610 KC8_19870 KC8_19870 KC8_09680 KC8_09680 KC8_09435 KC8_09435 acsA acsA KC8_00885 KC8_00885 KC8_01010 KC8_01010 KC8_01045 KC8_01045 KC8_01155 KC8_01155 KC8_03555 KC8_03555 accD accD KC8_06440 KC8_06440 KC8_06310 KC8_06310 KC8_05110 KC8_05110 pckA pckA KC8_04605 KC8_04605 KC8_04535 KC8_04535 KC8_04530 KC8_04530 accA accA fumC fumC KC8_14780 KC8_14780 ppc ppc gloB gloB KC8_14865 KC8_14865 glcB glcB KC8_02880 KC8_02880 KC8_02330 KC8_02330 KC8_05320 KC8_05320 KC8_05365 KC8_05365 KC8_01440 KC8_01440 KC8_13905 KC8_13905
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KC8_07095Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
KC8_07090Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa)
KC8_10380Unannotated protein. (706 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (512 aa)
KC8_15430Unannotated protein. (464 aa)
KC8_08650Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (550 aa)
KC8_08660Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (452 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (353 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (321 aa)
KC8_18010Unannotated protein. (464 aa)
KC8_18205Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
KC8_15150Unannotated protein. (222 aa)
KC8_15170Unannotated protein; Belongs to the pyruvate kinase family. (491 aa)
KC8_01910Unannotated protein. (491 aa)
KC8_11050Unannotated protein; Belongs to the PEP-utilizing enzyme family. (887 aa)
KC8_19610Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
KC8_19870Unannotated protein; Belongs to the aldehyde dehydrogenase family. (475 aa)
KC8_09680Unannotated protein. (111 aa)
KC8_09435Unannotated protein. (380 aa)
acsAUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (646 aa)
KC8_00885Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
KC8_01010Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
KC8_01045Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
KC8_01155Unannotated protein. (153 aa)
KC8_03555Unannotated protein; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (292 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (282 aa)
KC8_06440Unannotated protein; Belongs to the aldehyde dehydrogenase family. (495 aa)
KC8_06310Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
KC8_05110Unannotated protein. (474 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa)
KC8_04605Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
KC8_04535Unannotated protein. (624 aa)
KC8_04530Unannotated protein. (344 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (313 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
KC8_14780Unannotated protein. (754 aa)
ppcUnannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (896 aa)
gloBUnannotated protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (242 aa)
KC8_14865Unannotated protein. (137 aa)
glcBUnannotated protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (698 aa)
KC8_02880Unannotated protein; Belongs to the aldehyde dehydrogenase family. (485 aa)
KC8_02330Unannotated protein. (137 aa)
KC8_05320Unannotated protein. (137 aa)
KC8_05365Unannotated protein. (381 aa)
KC8_01440Unannotated protein. (504 aa)
KC8_13905Unannotated protein; Belongs to the aldehyde dehydrogenase family. (506 aa)
Your Current Organism:
Sphingomonas sp. KC8
NCBI taxonomy Id: 1030157
Other names: S. sp. KC8
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