STRINGSTRING
neuA neuA fabZ fabZ lpxA lpxA lpxB lpxB lpxH lpxH pseF pseF eptC eptC sdaA sdaA maf2 maf2 maf3 maf3 maf4 maf4 maf5 maf5 maf6 maf6 pseI pseI lpxC lpxC pgi pgi CINS_0292 CINS_0292 CINS_0294 CINS_0294 CINS_0304 CINS_0304 CINS_0305 CINS_0305 CINS_0308 CINS_0308 kpsC kpsC kpsS kpsS tpiA tpiA CINS_0411 CINS_0411 kdsA kdsA CINS_0494 CINS_0494 gmhB gmhB CINS_0617 CINS_0617 kdsC kdsC fbp fbp CINS_0771 CINS_0771 CINS_0772 CINS_0772 CINS_0773 CINS_0773 CINS_0778 CINS_0778 lpxD lpxD CINS_0859 CINS_0859 lpxK lpxK kdsB kdsB glmU glmU kdtA kdtA CINS_1035 CINS_1035 CINS_1119 CINS_1119 pckA pckA waaF waaF CINS_1188 CINS_1188 legF legF legG legG legI legI CINS_1197 CINS_1197 neuB neuB waaC waaC pseC pseC CINS_1270 CINS_1270 CINS_1271 CINS_1271
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
neuACMP-N-acetylneuraminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (223 aa)
fabZ3-hydroxyacyl-[acp] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
lpxAUDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (263 aa)
lpxBLipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (364 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Pfam match to PF12850.2 Metallophos_2. (242 aa)
pseFCMP-pseudaminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (233 aa)
eptCPhosphoethanolamine transferase; Pfam matches to PF08019.7 DUF1705, and to PF00884.18 Sulfatase. (516 aa)
sdaAL-serine deaminase I; Pfam matches to PF03313.10 SDH_alpha, and to PF03315.10 SDH_beta; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
maf2Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (572 aa)
maf3Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (626 aa)
maf4Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (623 aa)
maf5Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (578 aa)
maf6Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (652 aa)
pseIPseudaminic acid synthase; Pfam matches to PF03102.9 NeuB, and to PF08666.7 SAF. (345 aa)
lpxCUDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (294 aa)
pgiPhosphoglucose isomerase; Pfam match to PF00342.14 PGI. (407 aa)
CINS_0292Capsular biosynthesis sugar kinase; Pfam matches to PF00288.21 GHMP_kinases_N, and to PF08544.8 GHMP_kinases_C. (339 aa)
CINS_0294Pfam match to PF00483.18 NTP_transferase. (223 aa)
CINS_0304Putative phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Pfam matches to PF01326.14 PPDK_N, and to PF00391.18 PEP-utilizers. (773 aa)
CINS_0305Hypothetical protein, putative type I glutamine amidotransferase; Pfam match to PF00117.23 GATase. (199 aa)
CINS_0308Pfam match to PF01583.15 APS_kinase. (167 aa)
kpsCCapsular polysaccharide export protein (two domain); Pfam matches to PF05159.9 Capsule_synth, and to PF05159.9 Capsule_synth. (675 aa)
kpsSCapsular polysaccharide export protein; Pfam match to PF05159.9 Capsule_synth. (388 aa)
tpiATriosephosphate isomerase; Pfam match to PF00121.13 TIM. (226 aa)
CINS_0411Hypothetical protein, PMT family; Pfam match to PF13231.1 PMT_2. (384 aa)
kdsA3-deoxy-D-manno-octulosonate 8-phosphate synthase; Pfam match to PF00793.15 DAHP_synth_1; Belongs to the KdsA family. (267 aa)
CINS_0494Metallophosphatase; Pfam match to PF00149.23 Metallophos. (374 aa)
gmhBD,D-heptose 1,7-bisphosphate phosphatase; Pfam match to PF08645.6 PNK3P. (171 aa)
CINS_0617Hypothetical protein, putative family 8 glycosyltransferase; Pfam match to PF01501.15 Glyco_transf_8. (407 aa)
kdsC3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Pfam match to PF08282.7 Hydrolase_3. (162 aa)
fbpFructose-1,6-bisphosphatase I; Pfam match to PF00316.15 FBPase; Belongs to the FBPase class 1 family. (282 aa)
CINS_0771Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (412 aa)
CINS_0772Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (406 aa)
CINS_0773Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (395 aa)
CINS_0778Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (403 aa)
lpxDUDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (320 aa)
CINS_0859Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (413 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (303 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Pfam match to PF02348.14 CTP_transf_3; Belongs to the KdsB family. (241 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (430 aa)
kdtA3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (391 aa)
CINS_1035Aminotransferase, DegT/DnrJ/EryC1/StrS family; Pfam match to PF01041.12 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family. (360 aa)
CINS_1119Phosphoglycerol transferase; Pfam match to PF00884.18 Sulfatase. (657 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (524 aa)
waaFHeptosyltransferase II; Pfam match to PF01075.12 Glyco_transf_9. (306 aa)
CINS_1188Putative motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (635 aa)
legFCMP-legionaminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (235 aa)
legGGDP-2,4-diacetamido-2,4, 6-trideoxy-alpha-D-glucopyranose hydrolase / 2-epimerase; Pfam match to PF02350.14 Epimerase_2. (382 aa)
legILegionaminic acid synthase; Pfam matches to PF03102.9 NeuB, and to PF08666.7 SAF. (335 aa)
CINS_1197Hypothetical protein. (337 aa)
neuBSialic acid synthase (N-acetylneuraminic acid synthetase); Pfam matches to PF03102.9 NeuB, and to PF08666.7 SAF. (341 aa)
waaCHeptosyltransferase I; Pfam match to PF01075.12 Glyco_transf_9. (340 aa)
pseCUDP-2-acetamido-2, 6-dideoxy-beta-L-arabino-hex-4-ulose aminotransferase; Pfam match to PF01041.12 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family. (375 aa)
CINS_1270Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (403 aa)
CINS_1271Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (413 aa)
Your Current Organism:
Campylobacter insulaenigrae
NCBI taxonomy Id: 1031564
Other names: C. insulaenigrae NCTC 12927, Campylobacter insulaenigrae DSM 17739, Campylobacter insulaenigrae LMG 22716, Campylobacter insulaenigrae NCTC 12927, Campylobacter insulaenigrae str. NCTC 12927, Campylobacter insulaenigrae strain NCTC 12927
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