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| | queC | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (221 aa) |
| | queF | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (128 aa) |
| | thyX | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (210 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa) |
| | purB | Pfam matches to PF00206.15 Lyase_1, and to PF10397.4 ADSL_C; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (445 aa) |
| | bacA | Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa) |
| | pyrC | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (331 aa) |
| | eptC | Phosphoethanolamine transferase; Pfam matches to PF08019.7 DUF1705, and to PF00884.18 Sulfatase. (516 aa) |
| | purM | Phosphoribosylformylglycinamide cyclo-ligase; Pfam matches to PF02769.17 AIRS_C, and to PF00586.19 AIRS. (329 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (247 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (427 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (258 aa) |
| | maf2 | Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (572 aa) |
| | maf3 | Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (626 aa) |
| | maf4 | Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (623 aa) |
| | maf5 | Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (578 aa) |
| | maf6 | Motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (652 aa) |
| | CINS_0169 | Hypothetical lipoprotein (DUF3897 domain); Pfam match to PF13036.1 DUF3897. (209 aa) |
| | atpF | ATP synthase, F0 complex, b' subunit; Pfam matches to PF00430.13 ATP-synt_B, and to PF04156.9 IncA. (141 aa) |
| | atpF-2 | ATP synthase, F0 complex, b subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (170 aa) |
| | atpH | ATP synthase, F1 complex, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (173 aa) |
| | atpA | ATP synthase, F1 complex, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (501 aa) |
| | atpG | ATP synthase, F1 complex, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa) |
| | atpD | ATP synthase, F1 complex, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (484 aa) |
| | atpC | ATP synthase, F1 complex, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (130 aa) |
| | accD | acetyl-CoA carboxylase, carboxyltransferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (280 aa) |
| | lpxC | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (294 aa) |
| | murD | Pfam match to PF08245.7 Mur_ligase_M; Belongs to the MurCDEF family. (399 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (352 aa) |
| | accA | acetyl-CoA carboxylase, carboxyltransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa) |
| | CINS_0288 | dTDP-4-dehydrorhamnose 3,5-epimerase; Pfam match to PF00908.12 dTDP_sugar_isom. (180 aa) |
| | fcl | GDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (345 aa) |
| | CINS_0291 | Pfam match to PF01370.16 Epimerase. (312 aa) |
| | CINS_0292 | Capsular biosynthesis sugar kinase; Pfam matches to PF00288.21 GHMP_kinases_N, and to PF08544.8 GHMP_kinases_C. (339 aa) |
| | gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (197 aa) |
| | CINS_0294 | Pfam match to PF00483.18 NTP_transferase. (223 aa) |
| | CINS_0296 | Nucleotide sugar kinase; Pfam matches to PF00485.13 PRK, and to PF13419.1 HAD_2. (429 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (416 aa) |
| | carA | Carbamoylphosphate synthase, small subunit; Pfam matches to PF00988.17 CPSase_sm_chain, and to PF00117.23 GATase; Belongs to the CarA family. (372 aa) |
| | glmS | L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (599 aa) |
| | CINS_0408 | Putative nucleotide phosphoribosyltransferase; Pfam match to PF00156.22 Pribosyltran. (146 aa) |
| | CINS_0411 | Hypothetical protein, PMT family; Pfam match to PF13231.1 PMT_2. (384 aa) |
| | kdsA | 3-deoxy-D-manno-octulosonate 8-phosphate synthase; Pfam match to PF00793.15 DAHP_synth_1; Belongs to the KdsA family. (267 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Pfam match to PF00215.19 OMPdecase. (226 aa) |
| | purH | AICAR transformylase / IMP cyclohydrolase; Bifunctional; Pfam matches to PF01808.13 AICARFT_IMPCHas, and to PF02142.17 MGS. (510 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase PurLQS, PurL subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...] (725 aa) |
| | CINS_0494 | Metallophosphatase; Pfam match to PF00149.23 Metallophos. (374 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (373 aa) |
| | pycA | Pyruvate carboxylase, subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (479 aa) |
| | gmhB | D,D-heptose 1,7-bisphosphate phosphatase; Pfam match to PF08645.6 PNK3P. (171 aa) |
| | waaE | D,D-heptose 1-phosphate adenosyltransferase / 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (457 aa) |
| | coaX | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (207 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (511 aa) |
| | purD | Phosphoribosylamine-glycine ligase; Pfam matches to PF01071.14 GARS_A, and to PF02844.10 GARS_N, and to PF02843.11 GARS_C; Belongs to the GARS family. (416 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa) |
| | pyrD | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (353 aa) |
| | murJ | Lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (484 aa) |
| | ddlA | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (345 aa) |
| | pta | Phosphate acetyltransferase; Bifunctional; Pfam match to PF01515.14 PTA_PTB. (485 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa) |
| | CINS_0617 | Hypothetical protein, putative family 8 glycosyltransferase; Pfam match to PF01501.15 Glyco_transf_8. (407 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (190 aa) |
| | kdsC | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Pfam match to PF08282.7 Hydrolase_3. (162 aa) |
| | mrdA | Penicillin-binding protein 2; Pfam matches to PF00905.17 Transpeptidase, and to PF03717.10 PBP_dimer. (606 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (339 aa) |
| | ribF | Bifunctional riboflavin kinase / FMN adenylyltransferase; Bifunctional; Pfam matches to PF01687.12 Flavokinase, and to PF06574.7 FAD_syn, and to PF06574.7 FAD_syn; Belongs to the ribF family. (283 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase PurLQS, glutaminase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...] (216 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase PurLQS, PurS subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...] (78 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Pfam match to PF01259.13 SAICAR_synt; Belongs to the SAICAR synthetase family. (237 aa) |
| | CINS_0704 | Hypothetical protein. (313 aa) |
| | murA | UDP-N-acetylglucosamine enolpyruvoyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (194 aa) |
| | murG | N-acetylglucosaminyl transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (343 aa) |
| | CINS_0771 | Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (412 aa) |
| | CINS_0772 | Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (406 aa) |
| | CINS_0773 | Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (395 aa) |
| | CINS_0778 | Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (403 aa) |
| | lpxD | UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (320 aa) |
| | mltG | YceG-like protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (317 aa) |
| | CINS_0859 | Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (413 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (303 aa) |
| | kdsB | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Pfam match to PF02348.14 CTP_transf_3; Belongs to the KdsB family. (241 aa) |
| | dfp | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (387 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (430 aa) |
| | CINS_0959 | Putative RNA-binding protein (KH domain); Pfam match to PF13083.1 KH_4. (80 aa) |
| | kdtA | 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (391 aa) |
| | purE | 5-aminoimidazole ribonucleotide (AIR) carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (275 aa) |
| | pyrB | Aspartate carbamoyltransferase, catalytic subunit; Pfam matches to PF02729.16 OTCace_N, and to PF00185.19 OTCace; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (294 aa) |
| | pbpA | Penicillin-binding protein 1A; Bifunctional; Pfam matches to PF00912.17 Transgly, and to PF00905.17 Transpeptidase. (644 aa) |
| | pgp2 | Peptidoglycan LD-carboxypeptidase; Pfam match to PF03734.9 YkuD. (323 aa) |
| | murC | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (430 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (483 aa) |
| | atpE | ATP synthase, F0 complex, c subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (107 aa) |
| | gpsA | Glycerol 3-phosphate dehydrogenase; Pfam matches to PF07479.9 NAD_Gly3P_dh_C, and to PF01210.18 NAD_Gly3P_dh_N; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (300 aa) |
| | atpB | ATP synthase, F0 complex, a subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (226 aa) |
| | waaF | Heptosyltransferase II; Pfam match to PF01075.12 Glyco_transf_9. (306 aa) |
| | CINS_1188 | Putative motility accessory factor; Pfam match to PF01973.13 MAF_flag10. (635 aa) |
| | legF | CMP-legionaminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (235 aa) |
| | CINS_1197 | Hypothetical protein. (337 aa) |
| | CINS_1200 | NAD-dependent epimerase/dehydratase, ArnA decarboxylase-like protein; Pfam match to PF01370.16 Epimerase. (335 aa) |
| | neuA | CMP-N-acetylneuraminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (223 aa) |
| | waaM | Lipid A biosynthesis lauroyl acyltransferase; Pfam match to PF03279.8 Lip_A_acyltrans. (288 aa) |
| | waaC | Heptosyltransferase I; Pfam match to PF01075.12 Glyco_transf_9. (340 aa) |
| | pglK | Flippase; Pfam matches to PF00005.22 ABC_tran, and to PF00664.18 ABC_membrane. (564 aa) |
| | pglH | Pfam matches to PF00534.15 Glycos_transf_1, and to PF13439.1 Glyco_transf_4. (355 aa) |
| | pglJ | Pfam matches to PF00534.15 Glycos_transf_1, and to PF13439.1 Glyco_transf_4. (366 aa) |
| | pglB | Undecaprenyl-diphosphooligosaccharide--protein glycotransferase; Pfam match to PF02516.9 STT3. (711 aa) |
| | pglA | N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase; Pfam matches to PF00534.15 Glycos_transf_1, and to PF13477.1 Glyco_trans_4_2. (375 aa) |
| | pglC | N,N'-diacetylbacilliosaminyl-1-phosphate transferase; Pfam match to PF02397.11 Bac_transf. (200 aa) |
| | pglD | UDP-4-amino-4, 6-dideoxy-alpha-D-N-acetyl-D-glucosamine N-acetyltransferase; Pfam match to PF14602.1 Hexapep_2. (196 aa) |
| | pglE | UDP-4-amino-4, 6-dideoxy-alpha-D-N-acetyl-D-glucosamine transaminase; Pfam match to PF01041.12 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family. (386 aa) |
| | pglF | UDP-N-acetylglucosamine C-6 dehydratase; Pfam matches to PF02719.10 Polysacc_synt_2, and to PF13727.1 CoA_binding_3. (587 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (309 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (443 aa) |
| | dcd | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (186 aa) |
| | pseB | UDP-N-acetylglucosamine 4,6-dehydratase; Pfam match to PF02719.10 Polysacc_synt_2. (335 aa) |
| | CINS_1270 | Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (403 aa) |
| | CINS_1271 | Hypothetical protein (DUF2920 domain); Pfam match to PF11144.3 DUF2920. (413 aa) |
| | pseF | CMP-pseudaminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (233 aa) |
| | CINS_1275 | WbqC family protein; Pfam match to PF08889.6 WbqC. (241 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa) |
| | dxs | 1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (609 aa) |
| | lpxH | UDP-2,3-diacylglucosamine hydrolase; Pfam match to PF12850.2 Metallophos_2. (242 aa) |
| | lpxB | Lipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (364 aa) |
| | carB | Carbamoylphosphate synthase, large subunit; Pfam matches to PF02786.12 CPSase_L_D2, and to PF02787.14 CPSase_L_D3, and to PF02786.12 CPSase_L_D2, and to PF00289.17 CPSase_L_chain, and to PF00289.17 CPSase_L_chain, and to PF02142.17 MGS; Belongs to the CarB family. (1087 aa) |
| | lpxA | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (263 aa) |
| | fabZ | 3-hydroxyacyl-[acp] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa) |
| | queH | Hypothetical protein (DUF208 domain); Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (357 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (446 aa) |
| | queD | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Pfam match to PF01242.14 PTPS. (194 aa) |
| | queE | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (249 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (190 aa) |
| | fliI | Flagellar export apparatus, flagellum-specific ATP synthase FliI; Pfam match to PF00006.20 ATP-synt_ab. (435 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (202 aa) |
| | nrdB | Aerobic ribonucleoside-diphosphate reductase Ia, B2 protein subunit NrdB; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (340 aa) |
