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murB murB pseI pseI pgi pgi galU galU CINS_0255 CINS_0255 fcl fcl glmS glmS murA murA glmU glmU CINS_1035 CINS_1035 legF legF legG legG legI legI neuA neuA neuC neuC neuB neuB gne gne pglD pglD pglE pglE pglF pglF pseB pseB pseC pseC pseF pseF pseG pseG pseH pseH glmM glmM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (258 aa)
pseIPseudaminic acid synthase; Pfam matches to PF03102.9 NeuB, and to PF08666.7 SAF. (345 aa)
pgiPhosphoglucose isomerase; Pfam match to PF00342.14 PGI. (407 aa)
galUUTP--glucose-1-phosphate uridylyltransferase; Pfam match to PF00483.18 NTP_transferase. (274 aa)
CINS_0255Phosphomannomutase/phosphoglucomutase; Bifunctional; Pfam matches to PF02878.11 PGM_PMM_I, and to PF02879.11 PGM_PMM_II, and to PF02880.11 PGM_PMM_III, and to PF00408.15 PGM_PMM_IV. (455 aa)
fclGDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (345 aa)
glmSL-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (599 aa)
murAUDP-N-acetylglucosamine enolpyruvoyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (430 aa)
CINS_1035Aminotransferase, DegT/DnrJ/EryC1/StrS family; Pfam match to PF01041.12 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family. (360 aa)
legFCMP-legionaminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (235 aa)
legGGDP-2,4-diacetamido-2,4, 6-trideoxy-alpha-D-glucopyranose hydrolase / 2-epimerase; Pfam match to PF02350.14 Epimerase_2. (382 aa)
legILegionaminic acid synthase; Pfam matches to PF03102.9 NeuB, and to PF08666.7 SAF. (335 aa)
neuACMP-N-acetylneuraminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (223 aa)
neuCUDP-N-acetylglucosamine 2-epimerase; Pfam match to PF02350.14 Epimerase_2. (374 aa)
neuBSialic acid synthase (N-acetylneuraminic acid synthetase); Pfam matches to PF03102.9 NeuB, and to PF08666.7 SAF. (341 aa)
gneUDP-GlcNAc/Glc 4-epimerase; Pfam matches to PF01370.16 Epimerase, and to PF13950.1 Epimerase_Csub; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (328 aa)
pglDUDP-4-amino-4, 6-dideoxy-alpha-D-N-acetyl-D-glucosamine N-acetyltransferase; Pfam match to PF14602.1 Hexapep_2. (196 aa)
pglEUDP-4-amino-4, 6-dideoxy-alpha-D-N-acetyl-D-glucosamine transaminase; Pfam match to PF01041.12 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family. (386 aa)
pglFUDP-N-acetylglucosamine C-6 dehydratase; Pfam matches to PF02719.10 Polysacc_synt_2, and to PF13727.1 CoA_binding_3. (587 aa)
pseBUDP-N-acetylglucosamine 4,6-dehydratase; Pfam match to PF02719.10 Polysacc_synt_2. (335 aa)
pseCUDP-2-acetamido-2, 6-dideoxy-beta-L-arabino-hex-4-ulose aminotransferase; Pfam match to PF01041.12 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family. (375 aa)
pseFCMP-pseudaminic acid synthetase; Pfam match to PF02348.14 CTP_transf_3. (233 aa)
pseGUDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranosyl transferase. (274 aa)
pseHUDP-4-amino-4,6-dideoxy-beta-L-AltNAc o-acetyltransferase; Pfam match to PF13420.1 Acetyltransf_4. (155 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa)
Your Current Organism:
Campylobacter insulaenigrae
NCBI taxonomy Id: 1031564
Other names: C. insulaenigrae NCTC 12927, Campylobacter insulaenigrae DSM 17739, Campylobacter insulaenigrae LMG 22716, Campylobacter insulaenigrae NCTC 12927, Campylobacter insulaenigrae str. NCTC 12927, Campylobacter insulaenigrae strain NCTC 12927
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