STRINGSTRING
AKAW_01765 AKAW_01765 AKAW_04557 AKAW_04557 AKAW_04260 AKAW_04260 FEN1 FEN1 SLX4 SLX4 AKAW_02996 AKAW_02996 AKAW_02769 AKAW_02769 AKAW_02728 AKAW_02728 AKAW_01353 AKAW_01353 AKAW_05551 AKAW_05551 AKAW_00763 AKAW_00763 AKAW_10510 AKAW_10510 AKAW_08210 AKAW_08210 AKAW_07464 AKAW_07464 SLX1 SLX1 AKAW_05794 AKAW_05794
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKAW_01765DNA replication helicase Dna2. (1659 aa)
AKAW_04557Endonuclease. (335 aa)
AKAW_04260Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (850 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (818 aa)
AKAW_02996Exonuclease. (688 aa)
AKAW_02769DNA repair protein Mus81. (584 aa)
AKAW_02728Rad2-like endonuclease. (875 aa)
AKAW_01353XPG I-region protein. (678 aa)
AKAW_05551Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (753 aa)
AKAW_00763SAP domain-containing protein. (414 aa)
AKAW_10510DNA excision repair protein Rad2. (1135 aa)
AKAW_08210Zn(II)2Cys6 transcription factor. (728 aa)
AKAW_07464Acetyltransferase. (459 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (424 aa)
AKAW_05794DNA repair protein RAD1. (981 aa)
Your Current Organism:
Aspergillus kawachii
NCBI taxonomy Id: 1033177
Other names: A. kawachii IFO 4308, Aspergillus kawachii IFO 4308
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