STRINGSTRING
fabF fabF fabH3 fabH3 accB accB accC accC bioF bioF CCB68549.1 CCB68549.1 fabD fabD accD accD fabH1 fabH1 CCB68928.1 CCB68928.1 CCB68929.1 CCB68929.1 CCB68930.1 CCB68930.1 CCB69264.1 CCB69264.1 ltaE ltaE accA accA birA birA fabG fabG fabH2 fabH2 CCB70676.1 CCB70676.1 bioA bioA bioD bioD bioB bioB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fabF3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (417 aa)
fabH33-oxoacyl-[acyl-carrier-protein] synthase III protein FabH3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa)
accBAcetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
bioF8-amino-7-oxononanoate synthase; Biotin metabolism. (378 aa)
CCB68549.1Probable short-chain type dehydrogenase. (227 aa)
fabDMalonyl CoA-acyl carrier protein transacylase. (291 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (284 aa)
fabH13-oxoacyl-[acyl-carrier-protein] synthase III protein FabH1. (352 aa)
CCB68928.1Propionyl-CoA carboxylase, beta subunit. (513 aa)
CCB68929.1Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (480 aa)
CCB68930.1Biotin carboxyl carrier protein. (161 aa)
CCB69264.1Aminocarboxylic acid CoA-ligase. (419 aa)
ltaEThreonine aldolase. (339 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
birAProbable biotin--[acetyl-CoA-carboxylase] ligase. (243 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
fabH23-oxoacyl-[acyl-carrier-protein] synthase III protein FabH2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (336 aa)
CCB70676.13-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (386 aa)
bioAAdenosylmethionine--8-amino-7- oxononanoatetransaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (207 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (361 aa)
Your Current Organism:
Flavobacterium branchiophilum
NCBI taxonomy Id: 1034807
Other names: F. branchiophilum FL-15, Flavobacterium branchiophilum FL-15, Flavobacterium branchiophilum str. FL-15, Flavobacterium branchiophilum strain FL-15
Server load: low (22%) [HD]