STRINGSTRING
hisIE hisIE hisF1 hisF1 hisA hisA hisH1 hisH1 hisB hisB hisC hisC hisD hisD hisG hisG
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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hisIEHistidine biosynthesis bifunctional protein HisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. (199 aa)
hisF1Imidazole glycerol phosphate synthase subunit HisF1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisA1-(5-phosphoribosyl)-5-((5-phosphoribosylamino) methylideneamino)imidazole-4-carboxamide isomerase. (242 aa)
hisH1Imidazole glycerol phosphate synthase subunit HisH1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (194 aa)
hisBHistidine biosynthesis bifunctional protein HisB [Includes: Histidinol-phosphatase (EC 3.1.3.15); Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) (IGPD)]. (377 aa)
hisCHistidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (349 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa)
Your Current Organism:
Flavobacterium branchiophilum
NCBI taxonomy Id: 1034807
Other names: F. branchiophilum FL-15, Flavobacterium branchiophilum FL-15, Flavobacterium branchiophilum str. FL-15, Flavobacterium branchiophilum strain FL-15
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