Your Input: | |
| | rpoB | DNA-directed RNA polymerase beta subunit RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1270 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (119 aa) |
| | tdk | Thymidine kinase. (194 aa) |
| | CCB68198.1 | Protein of unknown function. (449 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (339 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (430 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (314 aa) |
| | hemD | Uroporphyrinogen-III synthase. (225 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (340 aa) |
| | hemF | Coproporphyrinogen oxidase. (308 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (944 aa) |
| | dinB | DNA polymerase IV, damage-inducible protein DinB; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (361 aa) |
| | hemB | Porphobilinogen synthase; Belongs to the ALAD family. (330 aa) |
| | CCB68289.1 | Protein of unknown function. (237 aa) |
| | atpG | ATP synthase gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (285 aa) |
| | atpA | ATP synthase alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (525 aa) |
| | atpH | ATP synthase delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (177 aa) |
| | atpF | ATP synthase B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (166 aa) |
| | atpE | ATP synthase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (65 aa) |
| | atpB | ATP synthase A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (378 aa) |
| | holB | Probable DNA polymerase III, delta prime subunit. (382 aa) |
| | coaX | Putative transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (244 aa) |
| | elaA | ElaA protein. (154 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (192 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH. (508 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase. (190 aa) |
| | upp | Uracil phosphoribosyltransferase. (215 aa) |
| | ribE | Riboflavin synthase, alpha subunit. (198 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (353 aa) |
| | CCB68424.1 | Probable coproporphyrinogen oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (375 aa) |
| | CCB68443.1 | Probable bifunctional protein : transcriptional regulator NadR family and of unknown function. (706 aa) |
| | CCB68457.1 | Protein of unknown function. (132 aa) |
| | nusA | Transcription elongation protein NusA; Participates in both transcription termination and antitermination. (417 aa) |
| | queG | Putative 4Fe-4S binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (302 aa) |
| | ygcM | Probable 6-pyruvoyltetrahydrobiopterin synthase. (136 aa) |
| | CCB68609.1 | Deoxyguanosine kinase; Probable bifunctional protein : 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase and deoxynucleoside kinase. (380 aa) |
| | CCB68611.1 | Probable deoxynucleoside kinase. (204 aa) |
| | CCB68613.1 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa) |
| | CCB68624.1 | Probable hydrolase (HAD superfamily). (199 aa) |
| | ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (339 aa) |
| | CCB68630.1 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa) |
| | prsA1 | Ribose-phosphate diphosphokinase. (313 aa) |
| | CCB68643.1 | Probable twin-arginine translocation pathway signal precursor protein. (544 aa) |
| | dfrA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (160 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (284 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa) |
| | nrdB | Ribonucleoside-diphosphate reductase, beta subunit. (325 aa) |
| | CCB68712.1 | Protein of unknown function. (163 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (384 aa) |
| | cinA | CinA-like protein; Belongs to the CinA family. (416 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (288 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | cyoE | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (299 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (274 aa) |
| | CCB70274.1 | Protein of unknown function. (792 aa) |
| | ribH | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (191 aa) |
| | CCB70345.1 | Protein of unknown function. (145 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa) |
| | nadE | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (263 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (660 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (159 aa) |
| | hemL | Glutamate-1-semialdehyde aminotransferase. (428 aa) |
| | CCB70403.1 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (162 aa) |
| | pdhC | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (528 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (333 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase. (275 aa) |
| | CCB70452.1 | Probable sugar phosphate nucleotydyl transferase. (390 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (436 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (369 aa) |
| | rpoA | DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (330 aa) |
| | queA | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (349 aa) |
| | cysG | Precorrin-2 dehydrogenase. (194 aa) |
| | cobA | Uroporphyrinogen-III C-methyltransferase. (277 aa) |
| | ygfA | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (188 aa) |
| | bioA | Adenosylmethionine--8-amino-7- oxononanoatetransaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (207 aa) |
| | rpoD | RNA polymerase sigma-70 factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa) |
| | CCB70689.1 | Protein of unknown function. (364 aa) |
| | rpoN | RNA polymerase sigma-54 factor RpoN. (488 aa) |
| | ribF | Bifunctional riboflavin biosynthesis protein RibF : Riboflavin kinase and FMN adenylyltransferase; Belongs to the ribF family. (321 aa) |
| | CCB70749.1 | Probable transmembrane protein of unknown function; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (212 aa) |
| | atpC | ATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane (by similarity). (93 aa) |
| | atpD | ATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (503 aa) |
| | CCB70764.1 | Putative phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa) |
| | CCB70859.1 | RNA-directed DNA polymerase; Retron-type reverse transcriptase. (503 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (386 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (361 aa) |
| | batB | BatB protein. (343 aa) |
| | batA | BatA protein. (333 aa) |
| | holA | Probable DNA polymerase III, delta subunit. (334 aa) |
| | pyrH | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (235 aa) |
| | rmlD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (285 aa) |
| | rmlC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (183 aa) |
| | purF | Amidophosphoribosyltransferase. (632 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (193 aa) |
| | thiL | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (349 aa) |
| | fcl | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (311 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (258 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (591 aa) |
| | CCB71023.1 | Probable 6-pyruvoyltetrahydrobiopterin synthase. (150 aa) |
| | nrdA | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (796 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (426 aa) |
| | CCB68767.1 | Probable transmembrane protein of unknown function. (179 aa) |
| | pyrC1 | Dihydroorotase. (447 aa) |
| | CCB68787.1 | Protein of unknown function. (247 aa) |
| | apaG | Protein ApaG. (128 aa) |
| | dnaE/dnaQ | Probable DNA polymerase III, alpha and epsilon subunits. (1514 aa) |
| | ugd | UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (463 aa) |
| | udk | Uridine kinase. (202 aa) |
| | CCB68876.1 | Bifunctional protein : WbnG and probable acetyltransferase. (476 aa) |
| | nusG | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (183 aa) |
| | rpoC | DNA-directed RNA polymerase beta' subunit RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1437 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa) |
| | CCB68950.1 | Probable transmembrane protein of unknown function. (171 aa) |
| | CCB68990.1 | Protein of unknown function. (146 aa) |
| | sprA | Putative adhesin precursor SprA. (2433 aa) |
| | kmo | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (448 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (190 aa) |
| | pdxJ | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (241 aa) |
| | ppnK | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (294 aa) |
| | folC | Bifunctional protein : Folylpolyglutamate synthase and Dihydrofolate synthase. (404 aa) |
| | CCB69120.1 | Hexapeptide transferase family protein. (191 aa) |
| | CCB69123.1 | Putative sugar epimerase. (129 aa) |
| | CCB69150.1 | Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa) |
| | CCB69176.1 | Putative transcriptional regulator. (196 aa) |
| | folP | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (284 aa) |
| | ygcF | Protein of unknown function YgcF; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (210 aa) |
| | CCB69216.1 | Protein of unknown function. (242 aa) |
| | phnP | PhnP protein. (254 aa) |
| | CCB69236.1 | Protein of unknown function. (482 aa) |
| | CCB69264.1 | Aminocarboxylic acid CoA-ligase. (419 aa) |
| | dnaN | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa) |
| | guaA | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. (509 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (517 aa) |
| | CCB69414.1 | Protein of unknown function. (78 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (539 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (248 aa) |
| | CCB69445.1 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | CCB69453.1 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa) |
| | CCB69459.1 | Protein of unknown function, putative methyltransferase. (393 aa) |
| | CCB69475.1 | Probable transmembrane protein of unknown function. (641 aa) |
| | pyrC2 | Dihydroorotase. (416 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (392 aa) |
| | CCB69538.1 | 5.2 Protein of unknown function similar to proteins from other organisms. (392 aa) |
| | CCB69541.1 | Protein of unknown function. (252 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) |
| | rocD | Ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (414 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (634 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1228 aa) |
| | dnaX | Probable DNA polymerase III subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (361 aa) |
| | CCB69635.1 | Probable DNA polymerase III subunit. (145 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamidesy nthase; Belongs to the SAICAR synthetase family. (316 aa) |
| | nadC | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. (285 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (816 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa) |
| | folE2 | GTP cyclohydrolase I. (223 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (339 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa) |
| | CCB69743.1 | Probable transmembrane protein of unknown function. (146 aa) |
| | ctaA | Cytochrome oxidase assembly protein. (337 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (151 aa) |
| | CCB69798.1 | Probable RNA-directed DNA polymerase. (442 aa) |
| | CCB69824.1 | Probable thiamine diphosphokinase. (220 aa) |
| | prpE | Propionate--CoA ligase; Catalyzes the synthesis of propionyl-CoA from propionate and CoA. (631 aa) |
| | acsA | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa) |
| | ribBA | Bifunctional enzyme : 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (377 aa) |
| | CCB69864.1 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa) |
| | dut | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa) |
| | cmk | Cytidylate kinase. (229 aa) |
| | nusB | N utilization substance protein B homolog (NusB protein); Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (303 aa) |
| | prsA2 | Ribose-phosphate diphosphokinase; Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1; Belongs to the ribose-phosphate pyrophosphokinase family. (275 aa) |
| | CCB69899.1 | Putative nicotinamide phosphoribosyl transferase; Belongs to the NAPRTase family. (484 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (193 aa) |
| | coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) |
| | CCB69909.1 | Protein of unknown function. (101 aa) |
| | CCB69920.1 | 5.2 Protein of unknown function similar to proteins from other organisms. (270 aa) |
| | CCB69923.1 | 5.2 Protein of unknown function similar to proteins from other organisms. (245 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (222 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (395 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (253 aa) |
| | CCB69951.1 | Probable DNA polymerase III subunit. (453 aa) |
| | CCB70073.1 | Protein of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. (189 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (398 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (253 aa) |
