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gcvH gcvH lpdA2 lpdA2 mvaC mvaC gcvP gcvP glnA glnA lpdA1 lpdA1 CCB68459.1 CCB68459.1 gcvT gcvT acsA acsA mdh mdh glyA glyA CCB68278.1 CCB68278.1 acnB acnB gltA gltA aceB aceB CCB70664.1 CCB70664.1 mutB mutB aceA aceA mutA mutA CCB68928.1 CCB68928.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
lpdA2Dihydrolipoyl dehydrogenase. (462 aa)
mvaCAcetyl-CoA acetyltransferase; Metabolic intermediate biosynthesis; mevalonate biosynthesis; R-mevalonate from acetyl-CoA: step 1/3; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
gcvPGlycine dehydrogenase (decarboxylating); Belongs to the GcvP family. (947 aa)
glnAGlutamate--ammonia ligase; Annotation automatically inferred by bidirectionnal best hit with 341 from FP; Belongs to the glutamine synthetase family. (729 aa)
lpdA1Dihydrolipoyl dehydrogenase. (467 aa)
CCB68459.1Probable lyase. (133 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (364 aa)
acsAAcetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
CCB68278.1Probable twin-arginine translocation pathway signal precursor protein; Belongs to the hyi family. (294 aa)
acnBAconitate hydratase; Carbohydrate metabolism; tricarboxylic acid cycle. (929 aa)
gltACitrate (Si)-synthase; Belongs to the citrate synthase family. (427 aa)
aceBMalate synthase; Glyoxylate bypass; second step (by similarity); Belongs to the malate synthase family. (533 aa)
CCB70664.1KHG/KDPG aldolase. (222 aa)
mutBMethylmalonyl-CoA mutase large subunit. (708 aa)
aceAIsocitrate lyase; Glyoxylate bypass; first step (by similarity). (426 aa)
mutAMethylmalonyl-CoA mutase small subunit. (454 aa)
CCB68928.1Propionyl-CoA carboxylase, beta subunit. (513 aa)
Your Current Organism:
Flavobacterium branchiophilum
NCBI taxonomy Id: 1034807
Other names: F. branchiophilum FL-15, Flavobacterium branchiophilum FL-15, Flavobacterium branchiophilum str. FL-15, Flavobacterium branchiophilum strain FL-15
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