(39 nodes) Regulation of mRNA catabolic process network (Aspergillus versicolor)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	A0A1L9PPD1	Uncharacterized protein. (273 aa)
	A0A1L9PNY5	PAT1 domain-containing protein. (826 aa)
	A0A1L9PLX3	Uncharacterized protein. (488 aa)
	A0A1L9PL95	RRM domain-containing protein. (632 aa)
	A0A1L9PL74	Uncharacterized protein. (502 aa)
	A0A1L9PKV4	Uncharacterized protein. (324 aa)
	A0A1L9PJL3	RING-type domain-containing protein. (957 aa)
	A0A1L9PJ86	RNase_PH domain-containing protein. (395 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (173 aa)
	A0A1L9PJ02	Uncharacterized protein. (252 aa)
	A0A1L9PVA9	Uncharacterized protein. (577 aa)
	A0A1L9PVP1	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (779 aa)
	A0A1L9PVS1	Endo/exonuclease/phosphatase domain-containing protein. (677 aa)
	A0A1L9PX68	Uncharacterized protein. (604 aa)
	A0A1L9PZ80	Uncharacterized protein. (271 aa)
	A0A1L9PS02	Uncharacterized protein. (249 aa)
	A0A1L9PPZ6	Uncharacterized protein. (619 aa)
	A0A1L9Q2V2	PUM-HD domain-containing protein. (858 aa)
	A0A1L9PT33	PUM-HD domain-containing protein. (871 aa)
	A0A1L9PSN3	Uncharacterized protein. (1632 aa)
	A0A1L9PSK0	Uncharacterized protein. (335 aa)
	A0A1L9PS59	Uncharacterized protein. (491 aa)
	A0A1L9PU49	RNase_PH domain-containing protein. (413 aa)
	A0A1L9PIP6	Uncharacterized protein. (295 aa)
	A0A1L9PI66	Uncharacterized protein; Belongs to the DEAD box helicase family. (463 aa)
	A0A1L9PHH0	ECR1_N domain-containing protein. (721 aa)
	A0A1L9PFS1	Uncharacterized protein. (2325 aa)
	A0A1L9PFL2	HRDC domain-containing protein. (770 aa)
	A0A1L9PAX7	Tr-type G domain-containing protein. (708 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1157 aa)
	A0A1L9P8V1	Uncharacterized protein. (169 aa)
	A0A1L9P740	Uncharacterized protein. (476 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (661 aa)
	A0A1L9P4R6	SAM domain-containing protein. (619 aa)
	A0A1L9P4K5	PUM-HD domain-containing protein. (1510 aa)
	A0A1L9P436	RRM domain-containing protein. (422 aa)
	A0A1L9P3Q7	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1096 aa)
	A0A1L9P3K7	Tr-type G domain-containing protein. (622 aa)
	A0A1L9P3B5	Nudix hydrolase domain-containing protein. (1226 aa)

Your Current Organism:

Aspergillus versicolor

NCBI taxonomy Id: 1036611
Other names: A. versicolor CBS 583.65, Aspergillus versicolor CBS 583.65

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L9P3B5	A0A1L9P740	A0A1L9P3B5	A0A1L9P740	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.586
A0A1L9P3B5	A0A1L9PHH0	A0A1L9P3B5	A0A1L9PHH0	Nudix hydrolase domain-containing protein.	ECR1_N domain-containing protein.	0.735
A0A1L9P3B5	A0A1L9PI66	A0A1L9P3B5	A0A1L9PI66	Nudix hydrolase domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.527
A0A1L9P3B5	A0A1L9PIP6	A0A1L9P3B5	A0A1L9PIP6	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.713
A0A1L9P3B5	A0A1L9PJ02	A0A1L9P3B5	A0A1L9PJ02	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.879
A0A1L9P3B5	A0A1L9PJ86	A0A1L9P3B5	A0A1L9PJ86	Nudix hydrolase domain-containing protein.	RNase_PH domain-containing protein.	0.760
A0A1L9P3B5	A0A1L9PKV4	A0A1L9P3B5	A0A1L9PKV4	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.978
A0A1L9P3B5	A0A1L9PNY5	A0A1L9P3B5	A0A1L9PNY5	Nudix hydrolase domain-containing protein.	PAT1 domain-containing protein.	0.978
A0A1L9P3B5	A0A1L9PPD1	A0A1L9P3B5	A0A1L9PPD1	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.669
A0A1L9P3B5	A0A1L9PS02	A0A1L9P3B5	A0A1L9PS02	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.739
A0A1L9P3B5	A0A1L9PS59	A0A1L9P3B5	A0A1L9PS59	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.867
A0A1L9P3B5	LSM1	A0A1L9P3B5	A0A1L9PJ71	Nudix hydrolase domain-containing protein.	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	0.879
A0A1L9P3Q7	A0A1L9P4K5	A0A1L9P3Q7	A0A1L9P4K5	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	PUM-HD domain-containing protein.	0.409
A0A1L9P3Q7	A0A1L9PFL2	A0A1L9P3Q7	A0A1L9PFL2	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	HRDC domain-containing protein.	0.601
A0A1L9P3Q7	A0A1L9PVP1	A0A1L9P3Q7	A0A1L9PVP1	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.	0.747
A0A1L9P436	A0A1L9P8V1	A0A1L9P436	A0A1L9P8V1	RRM domain-containing protein.	Uncharacterized protein.	0.546
A0A1L9P436	A0A1L9PI66	A0A1L9P436	A0A1L9PI66	RRM domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.500
A0A1L9P436	A0A1L9PL74	A0A1L9P436	A0A1L9PL74	RRM domain-containing protein.	Uncharacterized protein.	0.474
A0A1L9P436	A0A1L9PPZ6	A0A1L9P436	A0A1L9PPZ6	RRM domain-containing protein.	Uncharacterized protein.	0.403
A0A1L9P436	A0A1L9PVA9	A0A1L9P436	A0A1L9PVA9	RRM domain-containing protein.	Uncharacterized protein.	0.498