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A0A1L9TGQ4 A0A1L9TGQ4 A0A1L9SXH8 A0A1L9SXH8 A0A1L9SY02 A0A1L9SY02 A0A1L9SZV9 A0A1L9SZV9 A0A1L9T167 A0A1L9T167 A0A1L9T1M4 A0A1L9T1M4 A0A1L9T1X1 A0A1L9T1X1 A0A1L9T3J0 A0A1L9T3J0 A0A1L9T3Q8 A0A1L9T3Q8 A0A1L9T5B4 A0A1L9T5B4 A0A1L9T775 A0A1L9T775 A0A1L9T793 A0A1L9T793 A0A1L9T796 A0A1L9T796 A0A1L9T8E4 A0A1L9T8E4 A0A1L9T8J4 A0A1L9T8J4 A0A1L9TBZ5 A0A1L9TBZ5 A0A1L9TDE1 A0A1L9TDE1 A0A1L9TE52 A0A1L9TE52 A0A1L9TEI4 A0A1L9TEI4 A0A1L9TFD5 A0A1L9TFD5 A0A1L9TFI2 A0A1L9TFI2 A0A1L9TFL9 A0A1L9TFL9 A0A1L9TFM0 A0A1L9TFM0 A0A1L9TFP5 A0A1L9TFP5 A0A1L9TGD4 A0A1L9TGD4 A0A1L9TGL8 A0A1L9TGL8 A0A1L9THI9 A0A1L9THI9 A0A1L9THK7 A0A1L9THK7 A0A1L9THM6 A0A1L9THM6 A0A1L9TJD9 A0A1L9TJD9 A0A1L9TJJ0 A0A1L9TJJ0 A0A1L9TJQ8 A0A1L9TJQ8 A0A1L9TJX9 A0A1L9TJX9 A0A1L9TJZ9 A0A1L9TJZ9 A0A1L9TK01 A0A1L9TK01 A0A1L9TM48 A0A1L9TM48 A0A1L9TML3 A0A1L9TML3 A0A1L9TMQ8 A0A1L9TMQ8 A0A1L9TMT0 A0A1L9TMT0 A0A1L9TNT8 A0A1L9TNT8 A0A1L9TQH3 A0A1L9TQH3 A0A1L9TQU6 A0A1L9TQU6 A0A1L9TR54 A0A1L9TR54 A0A1L9TRI7 A0A1L9TRI7 A0A1L9TS16 A0A1L9TS16 A0A1L9TSJ7 A0A1L9TSJ7 A0A1L9TSL5 A0A1L9TSL5 A0A1L9TSN7 A0A1L9TSN7 A0A1L9TTR2 A0A1L9TTR2 A0A1L9TU90 A0A1L9TU90 A0A1L9TVB1 A0A1L9TVB1 A0A1L9TVB4 A0A1L9TVB4 A0A1L9TVD1 A0A1L9TVD1 A0A1L9TVJ1 A0A1L9TVJ1 A0A1L9TVL9 A0A1L9TVL9 A0A1L9TW35 A0A1L9TW35 A0A1L9TWA2 A0A1L9TWA2 A0A1L9TWJ6 A0A1L9TWJ6 A0A1L9TWL8 A0A1L9TWL8 A0A1L9TWX0 A0A1L9TWX0 A0A1L9TXB0 A0A1L9TXB0 A0A1L9TXL8 A0A1L9TXL8 A0A1L9TYY8 A0A1L9TYY8 A0A1L9TZU0 A0A1L9TZU0 A0A1L9U042 A0A1L9U042
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
protein homology
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A0A1L9TGQ4Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (851 aa)
A0A1L9SXH8AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (962 aa)
A0A1L9SY02Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (78 aa)
A0A1L9SZV9Protein transport protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy; Belongs to the SEC16 family. (1806 aa)
A0A1L9T167WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (309 aa)
A0A1L9T1M4Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (535 aa)
A0A1L9T1X1Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. (1474 aa)
A0A1L9T3J0ER lumen protein-retaining receptor. (213 aa)
A0A1L9T3Q8Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (1096 aa)
A0A1L9T5B4GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1104 aa)
A0A1L9T775GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1142 aa)
A0A1L9T793MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (446 aa)
A0A1L9T796zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (88 aa)
A0A1L9T8E4Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (264 aa)
A0A1L9T8J4AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (956 aa)
A0A1L9TBZ5Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (919 aa)
A0A1L9TDE1Uncharacterized protein. (907 aa)
A0A1L9TE52AP-1 complex subunit gamma. (840 aa)
A0A1L9TEI4Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (690 aa)
A0A1L9TFD5zf-Tim10_DDP domain-containing protein. (90 aa)
A0A1L9TFI2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (156 aa)
A0A1L9TFL9Plug_translocon domain-containing protein. (478 aa)
A0A1L9TFM0Autophagy-related protein 3. (364 aa)
A0A1L9TFP5MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (448 aa)
A0A1L9TGD4WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (379 aa)
A0A1L9TGL8AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (721 aa)
A0A1L9THI9Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family. (630 aa)
A0A1L9THK7Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (200 aa)
A0A1L9THM6zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (121 aa)
A0A1L9TJD9Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3170 aa)
A0A1L9TJJ0MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (639 aa)
A0A1L9TJQ8GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
A0A1L9TJX9AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (184 aa)
A0A1L9TJZ9Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. (728 aa)
A0A1L9TK01Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (959 aa)
A0A1L9TM48Uncharacterized protein. (582 aa)
A0A1L9TML3Uncharacterized protein. (1023 aa)
A0A1L9TMQ8Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1212 aa)
A0A1L9TMT0AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (757 aa)
A0A1L9TNT8Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (869 aa)
A0A1L9TQH3Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (405 aa)
A0A1L9TQU6Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (829 aa)
A0A1L9TR54Protein BCP1; Involved in nuclear export, actin cytoskeleton organization and vesicular transport; Belongs to the BCP1 family. (290 aa)
A0A1L9TRI7Adaptin_N domain-containing protein. (818 aa)
A0A1L9TS16Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (772 aa)
A0A1L9TSJ7Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
A0A1L9TSL5zf-Tim10_DDP domain-containing protein. (94 aa)
A0A1L9TSN7Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (124 aa)
A0A1L9TTR2Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (296 aa)
A0A1L9TU90AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
A0A1L9TVB1VPS37 C-terminal domain-containing protein. (247 aa)
A0A1L9TVB4Protein transport protein SFT2; Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex. Belongs to the SFT2 family. (216 aa)
A0A1L9TVD1Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (512 aa)
A0A1L9TVJ1Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (227 aa)
A0A1L9TVL9Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (1044 aa)
A0A1L9TW35Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (950 aa)
A0A1L9TWA2Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1030 aa)
A0A1L9TWJ6Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (516 aa)
A0A1L9TWL8Uncharacterized protein; Belongs to the VPS28 family. (859 aa)
A0A1L9TWX0Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (747 aa)
A0A1L9TXB060S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (511 aa)
A0A1L9TXL8Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (166 aa)
A0A1L9TYY8E3 ubiquitin-protein ligase PEP5. (950 aa)
A0A1L9TZU0Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family. (581 aa)
A0A1L9U042Importin subunit alpha; Belongs to the importin alpha family. (588 aa)
Your Current Organism:
Aspergillus sydowii
NCBI taxonomy Id: 1036612
Other names: A. sydowii CBS 593.65, Aspergillus sydowii CBS 593.65
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