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A0A1L9TVI5 A0A1L9TVI5 SPB1 SPB1 A0A1L9TQG6 A0A1L9TQG6 A0A1L9TQ68 A0A1L9TQ68 A0A1L9TMW5 A0A1L9TMW5 NOP7 NOP7 A0A1L9TJ20 A0A1L9TJ20 TSR3 TSR3 A0A1L9TGE2 A0A1L9TGE2 A0A1L9TGB6 A0A1L9TGB6 A0A1L9T7G6 A0A1L9T7G6 A0A1L9T1H8 A0A1L9T1H8 YTM1 YTM1 A0A1L9T0N4 A0A1L9T0N4 A0A1L9SZN5 A0A1L9SZN5 A0A1L9TX06 A0A1L9TX06 ERB1 ERB1 NAT10 NAT10 A0A1L9TSV7 A0A1L9TSV7
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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A0A1L9TVI5U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (719 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (804 aa)
A0A1L9TQG6U3 small nucleolar RNA-associated protein 22. (1112 aa)
A0A1L9TQ68rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (406 aa)
A0A1L9TMW5rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (638 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (679 aa)
A0A1L9TJ20H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (208 aa)
TSR3Ribosome biogenesis protein TSR3; Ribosome biogenesis protein required for processing 35S pre- rRNA at site D; Belongs to the TSR3 family. (366 aa)
A0A1L9TGE2KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (359 aa)
A0A1L9TGB6Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (500 aa)
A0A1L9T7G6Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (177 aa)
A0A1L9T1H8rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (114 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (487 aa)
A0A1L9T0N4U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (659 aa)
A0A1L9SZN5Uncharacterized protein. (356 aa)
A0A1L9TX06U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (289 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (792 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1006 aa)
A0A1L9TSV7ATP-dependent RNA helicase DBP10. (942 aa)
Your Current Organism:
Aspergillus sydowii
NCBI taxonomy Id: 1036612
Other names: A. sydowii CBS 593.65, Aspergillus sydowii CBS 593.65
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